1. PHARMACOLOGICAL TREATMENT OF NON-ACTION IN VIVO ENVIRONMENT AS RESEARCH
Munkhtsatsral TS ; Otgontsetseg T ; Enkh-amgalan P ; Enkhgerel D
Mongolian Pharmacy and Pharmacology 2015;6(1):36-39
AbstractIntroduction: Effects of medicine have many influential pharmaceutical and non-pharmaceutical factors. Term, “factors of medicine had been out because clinical research had proven that effect of medicine and reaction depends on medicine preparation technology, type of medicine, method to apply medicine. Prior to that, it was considered that quality of medicine depends on physical and chemistry conditions of medical ingredients, amount of active ingredients, etc. Bio digestion of medicine is an important criteria to take correct treatment, to reduce side effects in order to providing medical safety, to improve medicine quality, and to increase treatment impact. This study is about to prove that medical effect depends on medical factor particularly type of medicinePurpose: Aim is to study drug medical dissimilarity action in vivo enviromentMaterials and Methods: diuretics pharmacology tests 18-24gr 40 pieces weighting Balb /cshugamyn conducted on mice. Test "Monos" pharmacological sector in cooperation with the Institute for Research on drugs. Statistics by SPSS-20 software implementation and results of student criteria (p<0.05) was recognized and confirmed by one way ANOVA.Research is completedthe diuretics in the following the next sequence (Tryeindlinburg, 1980) 1. The research was conducted prior to the start of the test animals 0,3ml / 20gr doses of saline solution (NaCl 0.9%) treated with oral fluid pressure generated2. The research groups of injecting drug predicted doses experimental animals to drink5.3. Drinking the drug preparations 2.5 hours after the 30-minute intervals during the test animals urine test groups amount of urine of animals (p <0.05) compares.Result: Experimental animals, urine collected during the 30-minute interval of 2.5 hours, urine volume between the groups was compared with the control group.Administered medications, a comparative study of the Russian Federation " X1" acting industry furosemid make urinate "X2" Company "X3" LLC furosemid (p <0.05) compared to the control groups entails strong drugs furosemide make urinate consistent.Table form of furosemide drugs that acts comparative study of the Russian Federation "X1" acting industry furosemide make urinate "X4" Pharm Co Ltd furosemide (p <0.05) entails experimental groups with the control group furosemide make urinate strong comparison function (p <0.05)Conclusion:Medical activity that was different shows drug medical dissimilarity action, when comparing between types of pyroselid drug in various industries.Key words: Tablet form, active treatment, furosemide, injection, tablet, drug therapy acts as
2.Postpartum readmission rate
Odonzul Ts ; Batbold Ts ; Ariuntsetseg J ; Sergelen P ; Hangal Sh ; Ganbold S ; Munkh-Erdene L ; Erkembaatar T
Mongolian Medical Sciences 2020;193(3):28-34
Background:
Postpartum readmission rate has been increasing after both caesarean and vaginal delivery.
Postpartum diseases, in some cases with infection and anemia, result in hospital readmission. Also
it raises the issue associated with maternal hospital’s healthcare quality. There has lack of study
focusing on postpartum readmission. So we will study postpartum readmission rate.
Material and Methods:
112 patients who readmitted in Amgalan maternity hospital in Ulaanbaatar were involved in this study.
We used patient’s medical history to determine risk factors resulted in hospital readmission after
caesarean and vaginal therapy.
Results:
The mean age of women delivered by cesarean was 30.2±7.32 and vaginal delivery’s was 28.3±7.21.
34.8 percent of women who readmitted after vaginal delivery had 1-3 readmission days and 56.5
percent was 4-6 days and 8.7 percent was 7-10 days. Readmission day for women delivered
by caesarean was 1-3 days in 21.2 percent of these, 4-6 days in 56.1 percent and 7-10 days in
19.7 percent. The mean readmission day of women delivered by vaginal delivery was 4.73±1.61
(mean±SD) and the mean of women delivered by caesarean delivery was 5.54±2.34 (mean±SD). In
each category, there had 24.2-28.3 percent cases with lochia. Women who had caesarian delivery
were infected their scar with 24(36.3) cases. Renal urinary system infection had in 12(26.0) women
delivered by vaginal delivery.
Conclusion
58.9 percent of total readmissions cases were caesarean and 41.1 percent was vaginal delivery.
Lochia and renal urinary infection had influence in readmission after vaginal delivery. Also both lochia
and infected wound impacted on postpartum readmission after caesarian delivery.
3. Assessment of biliary complication after liver transplantation in Mongolia
Bat-Ireedui B ; Ganzorig B ; Batsaikhan B ; Erdene S ; Batchuluun P ; Amgalan L ; Sergelen O
Journal of Surgery 2016;19(1):10-18
Introduction: A considerable proportionof adult living donor liver transplantation(LDLT) recipients experience biliarycomplication (BC), but there are few reportsregarding BC based on long-term studies ofa large LDLT population.Methods: The present study examinedBC incidence, from 16 adult and pediatricpatients (14 right liver and 2 left liver graft )between 2011 and 2016 First Central Hospitalof Mongolia.Results: The mean follow-up period was36±1 months. First Central Hospital has DDanastmosis (n=22) double DD (n=2) singlehepaticojejunostomy (n=3). There 3 caseshave biliary stricture after operation. One ofthe 3 cases has biliary laek 2 months laterafter the operation.Conclusion: Close surveillance for BCappears necessary for at least the first 3 yrafter LDLT. In terms of anastomotic stenosisrisk, HJ appears a better choice than DD forright liver grafts involving ducts less than 4mm in diameter.
4.Relationship between respiratory and circulatory diseases among adults and air temperature
Nyam-Osor D ; Oyunchimeg M ; Nyamsuren L ; Amgalan G ; Enkhtuya P ; Burmaajav B
Mongolian Medical Sciences 2012;162(4):36-42
BackgroundHuman-induced climate change will affect the lives of most populations in the next decade and beyond. The impact of meteorological conditions on human health has been reported globally. There is a need to conduct surveys for correlation between climate change and human health.GoalTo study the impact of air temperature on human health in selected aimags and city districts.Materials and MethodsIn order to study how climate change and air quality parameters affect human health we selected Zavhan, Selenge, Dornod, and Umnugobi aimags which represent different climate zones and 2 districts of Ulaanbaatar city during 2009-2011. All data for respiratory system disease J00-J99, circulatory system disease I00-I99, were collected from soum, district’s hospital, and aimag and soum’s Department of health.ResultsDuring the study period, a total number of 8649 incidences of respiratory disease are registered. From them 74.2 percent are influenza and pneumonia (J09-J18), 17.6 percent are other acute lower respiratory infections (J20- J22), and 8.2 percent are asthma (J45-J45.9). For cardiovascular disease 15288 incidences are registered. From them 65.6 percent are hypertensive disease (I10-I15), 23.6 percent are ischemic heart disease, and 10.8 percent are cerebrovascular diseases (I60-I69). The lower the air temperature, higher the incidence of influenza and pneumonia, acute lower respiratory infections, hypertensive, and ischemic heart disease.ConclusionsCold weather is correlated with a higher incidence of respiratory and cardiovascular diseases.
5.Tannin rich medicinal plants
Enkh-Amgalan P ; Telmen D ; Altan-Erdene N ; Selenge E
Mongolian Pharmacy and Pharmacology 2022;20(1):78-85
Abstract
Secondary metabolites present in the plants are predominantly responsible for treating various ailments. Secondary metabolites are also called as plant constituents or natural compounds which exert significant pharmacological and toxicological effects in humankind. The chemical compounds present in the plant sources are categorized as primary and secondary metabolites based on the chemical structure and biosynthetic derivation. These substances are called plants secondary metabolites. One of the most important of secondary metabolites is Tannins. Tannins are phenolic compounds, secondary metabolites of plants widespread in terrestrial and aquatic natural environments. As they can be found in plenty of plants and herbs, they have been traditionally used for medicinal and other purposes, such as the leather industry. This fact is explained by the fact that they exert plenty of different biological activities and, thus, they entail a great potential to be used in the food, nutraceutical, and pharmaceutical industry.
Among the biological activities of tannins, the most relevant ones are antioxidant, anti-inflammatory, anti-diabetic, cardioprotective, healing and antimicrobial (antiviral and antibacterial)
Consequently, this review article is directed towards the description of the biological activities exerted by tannins as they could be further extracted from by-products of the agri-food industry to produce high-added-value products.
6.A review on medicinal plants of the genus Betula
Enkh-Amgalan P ; Munkhbayar N ; Tserendulam L ; Makhpal A ; Selenge E
Mongolian Pharmacy and Pharmacology 2021;19(2):22-30
Abstract
Trees and shrubs of the genus Betula (Betulaceae) inhabit various ecosystems in temperate and boreal climate zones of the northern hemisphere. The healing properties of Betula bark and bark extracts have been known for a long time in traditional medicine in different parts of the world. Several species of Betula have traditionally been used for the treatment of various inflammatory diseases including arthritis. The purpose of this review is to provide updated, comprehensive and categorized information on the botany, traditional uses and phytochemical research of Betula species in order to explore their therapeutic potential and evaluate future research opportunities.
7.Outcomes of retinopathy of prematurity screening at National Center For Maternal And Child Health
Tsengelmaa Ch ; Erdenetuya G ; Tsogzolmaa G ; Gantuya M ; Amgalan P ; Enkhtuya S ; Altantuya Ts ; Bayalag M
Innovation 2021;14(1-Ophthalmology):22-25
Purpose:
To investigate the outcomes of ROP screening of retinopathy of prematurity (ROP).
Methods:
This was a prospective of prematurity infants screened ROP from 2020 April 13th to
April 28th 2020 and from 2020 June 08 th to June 22th 2020 and prospective cohort study of
premature infants with treatment-requiring ROP who received intravitreal injections, laser surgery.
Demographic factors, diagnosis and clinical course were recorded. Indirect ophthalmoscopy
and Retinal imaging was performed using RetCam (Natus Medical, Pleasanton, CA) and
images were taken. Each eye was evaluated by the pediatric ophthalmologist and aimag’s
ophthalmologist for the presence or absence of ROP, zone of vascularization, stage, plus disease,
and aggressive posterior ROP (AP-ROP). The diagnosis and classification of ROP for this current
study were determined by examination using indirect ophthalmoscopy, and treatment plans
were determined according to the International Classification for ROP and the Early Treatment for
ROP Study (ET-ROP).2,13
Results:
A total of 90 premature infants with BW ≤ 2000g and/or GA ≤ 34 weeks were screened for
ROP during the study period. 8 (8.8%) of the 90 infants screened required treatment. The 8 infants
who received ROP treatment had a mean GA of 28.5 ± 1.7 weeks, mean BW of 1237.5 ± 125.42g,
mean PMA of 36 weeks and mean follow-up time of 2 months.
Conclusion
After treatment, resolution of ROP was noted in approximately 100 % of the patients
who had treatment-requiring ROP.