1.Change in ovarian reserve after treatment of endometrioma
Munkhbayar Ch ; Amarjargal O ; Munkhbayarlakh S ; Yanjinsuren D
Mongolian Medical Sciences 2020;191(1):26-31
Background:
Endometriosis is a condition in which cells in the endometrium, layer of tissue normally covers uterine
cavity, which grows outside to ovaries and other pelvic organs [1-4]. That may happen chronic pelvic
pain, adhesion and pelvic organs dysfunction which leads to infertility later life [1-4]. In worldwide,
19-45 aged women have endometriosis, which is counted for 176 million, from 44% women have
ovarian endometrioma [5]. In our country, 56% women received laparoscopic surgery due to ovarian
cysts, which is diagnosed endometrioma. In recent years, ovarian endometriosis treated by synthetic
progestin, gonadotropin analogues, combined contraceptive pills, intra-uterine device containing with
progestin, and non-steroid anti-inflammatory drugs and laparoscopic surgeries [6, 7]. Serum antimullerian hormone (AMH) is key marker to define ovarian reserve, which correlates ovarian number of antral follicle counts [6, 7].
Material and Methods:
We studied 129 patients who has diagnosed with ovarian endometrioma, aged 20-46 years, using
case-control study design. There are 4 groups with medication and surgeries.
Approval for the study was obtained from the review board and the ethics committee of MNUMS. All
the recruited patients provided their informed written consents.
Results:
When treatment groups were compared, level of AMH before synthetic progestin therapy was 3.48±0.9
and after it 3.41±1.0 (p-0.456), and that was before non-steroid anti-inflammatory drugs 3.68±0.8 and
after it 3.11±0.8 ng/ml (p-0.212). Before laparoscopic surgeries for severe endometrioma, average
level of AMH was 2.3±1.8ng/ml for synthetic progestin therapy group and it was 1.68±0.2ng/ml (p-0.007) after surgical peeling of endometrioma. For patients of 4th group who had not taking oral
synthetic progestin before laparoscopic surgeries average level of AMH was 3.11±1.88 ng/ml before
surgery and it became 2.21±0.28 ng/ml (p-0.005). Level of СА-125 marker was before medical
therapy for group 1 was 37,9±5,25 IU/ml and after therapy - 20,6±2,03 IU/ml. For group 2 it was
69,9±9,79IU/ml and 35.1±6.76 IU/ml respectively. Average level for group 4 before surgical treatment
it was 96.6±36.6 IU/ml, and after surgery became 25.71±2.96 IU/ml, and that for group 3 was before
surgery 102±29.1 IU/ml and decreased after surgery to 29.2±4.15 IU/ml.
There are significant reduction of pain in patients who received synthetic progestin (p=0.001) groups.
Serum AMH were 3.48±0.9 before treatment and 3.41±1.0 after treatment respectively (p=0.456).
Prior treatment of laparoscopic surgery with progestin 3 months, it decreases abdominal lower
pain (p=0.001) and dysmenorrhea (p=0.001). Serum AMH level were 3.11±1.8 before surgery and
2.21±0.2 after surgery,respectively, (p=0.005).
Conclusion
1. There were little decrease in level of antimullerian hormone and less risk for ovarian reserve when
mild endometrioma was treated with synthetic progestin and non-steroid anti-inflammatory drugs in
two groups.
When severe and middle degree of endometrioma was treated with laparoscopic surgery there were
significant decrease of antimullerian hormone, but it was less in group that had synthetic progestin
therapy before surgery and it was more effective that surgical therapy without preparation.
2. Comparison of Serum level of СА-125, marker of ovarian tumor, was decreased less in group of
non-steroid anti-inflammatory drugs, and was decreased more or it was more effective.
2.Study of influencing factors of the maternal, infant and placenta weight
Jargalsaikhan B ; Otgonbayar L ; Gandolgor B ; Uurtiintuya B ; Oyunsuren E ; Otgontsetseg B ; Tsolmon G ; Amarjargal B ; Tegshjargal S
Mongolian Medical Sciences 2017;181(3):10-14
Introduction :
In the last years other country scientists told about not only determine infant weights, need to interest
correlation between maternal weight, height and infant weight. In our country few research articles posted
about anthropometry of obstetrics and gynecology. Our study aim is determine maternal weight, infant
weight, placenta weight and assess factors affecting roles on maternal story of “Amgalan” Maternity
Hospital in 2014-2015.
Goal:
The current study aimed at assessing maternal weight, infant weight, placenta weight and evaluating the
effect of factors leading to it.
Materials and Methods:
The data was already collected from “Amgalan” Maternity Hospital using maternal history and record and
it was collected measuring general physical characteristics such as body weight and height, infant weight,
placenta weight and body circumferences. We used retrospective method and collected statistical data
was analyzed using SPSS 21.0 software.
Results:
Of total 964 study participants aged 18-45. The average age of participants was 29.6 ± 5.8 years old and
49.7% (n=479) was working during pregnancy, 45.7% (n=441) hadn’t works, 4.6% (n=44) was student.
The average weight of mothers was 75.4±11.5, weight of infants was 3439.5±456, weight of placenta
was 685±129. The following factors affected maternal and infant weights: lower education, working, early
and late pregnancy complication. Maternal weight had a low direct correlation with infant weight (r=0.267,
p<0.01) and placenta weight (r=0.208, p<0.01). In our study maternal height had a low direct correlation
with infant weight(r=0.173, p<0.01) and infant weight had a moderate direct correlation with placenta
weight (r=0.376, p<0.01).
Conclusions
1. The average maternal weight was 75.4±11.5, infant weight was 3539.5±456, placenta weight was 685±129.
2. The following factors affected maternal and infant weights: lower education, working status, early and late pregnancy complications.
3. Maternal weight had a little direct correlation with infant weight (r=0.267, p<0.01) and placenta
weight (r=0.208, p<0.01).
3.Visual and anatomical outcomes of vitrectomy surgery in rhegmatogenous retinal detachment
Oyunzaya L ; Amarjargal S ; Zolboo A ; Khongorzul G ; Balmira Ye ; Tseevanjid Ya ; Surenjav Z ; Ganzaya G
Innovation 2021;14(2-Ophthalmology):12-15
Background:
To determine the visual and anatomical outcomes after rhegmatogenous retinal
detachment surgery.
Methods:
Case files of patients who had surgery for rhegmatogenous retinal detachment at the
3rd state central hospital May 2019 and May 2021 were reviewed. Information obtained included
age, sex, presenting and post-operative visual acuity, anatomical reattachment, post- operative
complications and causes of treatment failure.
Results:
Risk factors for retinal detachment included myopia in 8 eyes (32%), trauma in 7 eyes
(28%), prior cataract surgery in 2 eyes (8%). 22 eyes (88%) presented with macula off while 3 eyes
(12%) presented with macula partly or completely attached. Visual acuity at presentation was
<0.01 in 15 eyes (60%). Following surgery, retina was attached in 23 eyes (92%) and remained
detached 2 eyes (8%). Visual acuity after surgery was 0.1< 17 eyes, 0.4< 7 eyes. Visual acuity
improved in 23 eyes (84%), remained the same in 2 eyes (8%).
Conclusion
Myopia and trauma are important risk factors for Rhegmatogenous Retinal
Detachment. Majority of patients in this setting presented late with Rhegmatogenous Retinal
Detachment and this was responsible for relatively poor visual outcomes despite good anatomical
results after surgery. Proper screening of eyes at risk and education of patients is important for
preventing visual loss due to retinal detachment.