Objective: To investigate the prevalence of metabolic diseases among residents in Moyu County, Hotan Prefecture, Xinjiang Uygur Autonomous Region, so as to provide the evidence for developing the control strategy for metabolic diseases. Methods: The demographic features, laboratory examinations and B-mode ultrasonographic examinations of the liver and gall bladder were collected from residents at ages of 18 years and older in Moyu County through the hospital-based medical records system. The prevalence of metabolic diseases was estimated, including obesity, hypertension, diabetes, dyslipidemia and fatty liver, and the factors affecting the development of metabolic diseases were identified using a multinomial logistic regression model. Results: Totally 281 803 residents were included in the study, including 129 549 men ( 49.97% ) and 152 254 women ( 54.03% ) and with a median age of 37.00 years ( interquartile range, 22.00 years ). The overall prevalence of metabolic diseases was 47.66%, and the prevalence rates of obesity, hypertension, dyslipidemia, fatty liver and diabetes were 25.72%, 24.77%, 12.30%, 12.05% and 5.49%, respectively, which appeared a tendency towards a rise with age ( χ2trend = 11 243.73, 14 086.41, 2 109.70, 6 631.22, and 2 011.15, all P<0.001 ). There were 73 811 residents suffering from one metabolic disease (26.19%), and 60 495 residents with two and more metabolic diseases ( 21.47% ). Multinomial logistic regression analysis showed that gender ( OR=0.870; 0.796 ), age ( OR: 1.703-8.701; 2.952-18.846 ), marital status ( OR: 1.397-1.845; 1.460-2.377 ) educational level ( OR: 0.891-0.937; 0.920-0.924 ), occupation ( OR: 1.177-1.270; 1.114-2.099), family history ( OR=1.136; 1.390), drinking frequency ( OR: 2.038; 1.395-2.574 ) and central obesity ( OR=3.448; 14.352 ) were factors affecting the development of one or more metabolic diseases. Conclusion The prevalence of metabolic diseases is high among residents in Moyu County. Men, the elderly, a low education level and unhealthy lifestyles may increase the risk of metabolic diseases.

Abstract: Objective To understand the prevalence and influencing factors of major chronic diseases among Kirgiz residents in Aheqi County, Xinjiang, and to provide theoretical basis for the prevention and control of chronic diseases in this area. Methods　The data of residents in Aheqi County, Kizilsu Kirgiz Autonomous Prefecture, Xinjiang in 2020 for health checkup were selected, and the permanent residents of Kirgiz nationality aged ≥18 were selected as the survey objects, and the prevalence of major chronic diseases and their influencing factors were analyzed by Logistic regression model. Results　A total of 21 935 patients were enrolled, and 10 602 patients suffered from chronic diseases with a prevalence rate of 48.33%, including 4 929 cases of hypertension with a prevalence rate of 22.47%, 4 238 cases of obesity with a prevalence rate of 19.32%, 3 610 cases of dyslipidemia with a prevalence rate of 16.46%, 1 632 cases of anemia with a prevalence of 7.44%, and 1 236 cases of type 2 diabetes with a prevalence of 5.63%. The prevalence of hypertension, obesity, dyslipidemia and type 2 diabetes increased with age, while the prevalence of anemia decreased with age (P<0.01). The prevalence of hypertension dyslipidemia and type 2 diabetes was higher in males than in females, and the prevalence of obesity and anemia was higher in females than in males, with statistical significance (P<0.01). Logistic regression analysis showed that 30-<40 years old (OR=1.836, 95%CI: 1.565-2.034), 40-<50 years old (OR=2.916, 95%CI: 2.613-3.255), 50-<60 years old (OR=5.244, 95%CI: 4.651-5.913), 60 years old and above (OR=10.866, 95%CI: 9.533-12.385), government personnel (OR=1.789, 95%CI: 1.405~2.279), professional and technical personnel (OR=1.774, 95%CI:1.372-2.295), the office staff (OR=1.923, 95%CI: 1.418-2.607) occasional alcohol consumption (OR=1.157, 95%CI: 1.055-1.270) and occasional exercise (OR=1.498, 95%CI: 1.238-1.812) were risk factors for chronic disease. Conclusion　The prevalence of chronic diseases among residents in Aheqi County of Xinjiang is at a low level. Local health institutions have strengthened health education and publicity on multiple chronic diseases and the prevention and control of anemia among young and middle-aged women.