INTRODUCTION:Alcohol (EtOH) use disorders (AUDs) represent a substantial public health problem worldwide. Over 76million people present with AUDs 2.5 million deaths were attributed to alcohol (World Health Organization,2010). Channadshelshi has been used for treatment of alcohol-related, liver disease and intoxication intraditional medicine.GOAL:To determine effect of channadshelshi on voluntary alcoholic wistar rats.MATERIALS AND METHODS:To examine acute toxicity of Channadselshi were used V.P.Prozorovsky express method (1978) andOECD (2001).Voluntary EtoH consumption measurement (two-bottle choice, intermittent access to EtOH paradigm inwistar rats). Water and 20% ethanol were presented in 200 mlgraduated plastic cylinders with stainlesssteeldrinking spouts.The experiment period was 10 weeks total. EtOH consumption was expressed asgrams of EtOH consumed per kilogram of body weight/day.Elevated plus maze. Anxiety associated with EtoH withdrawalwas measured on EPM The mazewaselevated 1 m above the floor and contained four 50 cm long, 10 cmwidearms arranged at rightangles. The closed arms had opaque walls 30cm high, extending the length of the arm. At the time of thetest, eachanimal was placed in the center of the maze facing an open arm andallowed to explore for a5 min session. During this 5 min test session, theanimal’s number of arm entries and time spent in eacharm per entry was recorded on a camera.Pentylenetetrazol (PTZ) 100 mg/kg dose used in this study was determined as the dose that inducedseizures and protection against mortality in miceThe experimental protocol was approved by the Ethics Committee of the MNUMS. (№ 14-11/1À)RESULTS:LD50 of Channadselshi extract was found to be LD50=2.58 (2.1-3.2) gr/kg by V.P.Prozorovsky expressmethod (1978). Channadselshi was no acute toxic by OECD (2001).Ten and four weeks oral administration of Channadselshi (200 mg/kg) significantly (P<0.01) decreasedthe consumption of ethanol and significantly (P<0.01) increased time spent in open arm (EPM) involuntary alcoholic wistar rat compare to control.The time (sec) of latency the generalized convulsion were significantly (P<0.01) increased ofChannadselshi compare to control. The percent of protection against mortality were 80% in PTZinduced seizure in mice.CONCLUSIONS:1. Our study showed that Channadselshi hasreduced consumption of ethanol in voluntary alcoholicwistar rat.2. Channadselshi has central nervous system protection effect against PTZ induced seizure in mice.

Children with impaired hearing have communication and learning difficulty due to delay in the development of receptive and expression communications. Communication difficulties can often lead to social isolation and poor self-estimation. Oral health status in children with impaired hearing tends to be poor due to several reasons as difficulty of adequate training of caregiving parents, parents luck of information and effort. Aim: To study oral health status and oral education level among students of special school №29 for disabled children.A cross-sectional descriptive study. 224 students aged 6-22 years were selected for this study. Participants were subjected to oral examination and were asked to answer to the questionnairePrevalence of caries and DMFT index, dental plague, occlusion and the oral education levels were assessed. The caries prevalence was 95.9%, and the mean DMFT index was 5.5. Dental plaques were identified in 31.7-49.2% of subjects differing among age groups. Among examined children, 32% of subjects had a malocclusion and 18 children underwent cleft lip palate surgical treatment. According to questionnaire 21% of subjects reported that tooth brushing is not significant measure to maintain oral health, which shows that oral education level among subjects was low. Oral health status of children with impaired hearing was in a level comparable to that of healthy children, although the incidence of cleft lip and palate and gingivitis were higher.

Background: In traditional Mongolian medicine, ischemic heart disease are treated by balancing the body, promoting the f low of khii and blood, improving the metabolism, suppressing inflammation, increasing heart strength, relieving pain, and treating the disease according to its actual condition. Therefore, a study was conducted to investigate the effects of traditional medicines Heart Agar-8 and Zandan-3 on ischemic heart disease. Aim: Studying the therapeutic effects of some traditional medicines used in the treatment of ischemic heart disease. Materials and Methods: Clinical trial was performed in an uncontrolled, single-centered, and open-study design. A total of 48 patients with ischemic heart disease who met the inclusion criteria participated in the study. The study was conduct ed by giving people 3 grams of Heart Agar-8 and 3 grams of Zandan-3 medicine, each once a day, for a total of 3 weeks. The results of the study were assessed before and after the study using the SAQ questionnaire, the chronic coronary syn dromes (CCS) questionnaire, 6-minute walk test, and electrocardiogram. The research was conducted in accordance with the appropriate ethical approvals (No. 24-25/03-01), (No. 2024-077) and confirmed by an informed consent form. Clinical trial research results were processed using T-test, Paired T-test. Results: A total of 48 people diagnosed with ischemic heart disease (TMK00.2) were included in the study. The average age of the study participants was 53.94±1.69, with the youngest being 44 and the oldest being 60. Regarding the gender of the respondents, 15 (31.25%) were men and 33 (68.75%) were women. When comparing pre-treatment results with post-treatment results using the SAQ, there were improvements in mobility (p<0.000), chest stability (p<0.012), chest pain (p<0.000), treatment satisfaction (p<0.001), and quality of life assessment (p<0.000). When assessing chronic cor onary syndrome in people, 44 or 91.6% of the total number of people included in the study had a level II score before treatment, while 37 or 77.08% had a level I score after treatment, which was a statistically significant difference between the pre-treatment and post-treatment indicators (p<0.034). Cardiac function was assessed by the 6-minute walk test, which was 393.9±36.73 meters before treatment, or grade II, but improved to 456.83±48.6 meters after treatment, or grade I (p<0.000). Conclusions 1. People diagnosed with ischemic heart disease have shown statistically significant results when given the traditional medicine Heart Agar-8 and Zandan-3 in combination with clinical trials. 2. The study participants experienced statistically significant improvements in mobility, usual activities, pain, and depression, improved quality of life, and increased functional status in coronary heart disease.

Background: Medicines with unique healing methods and European medical treatments and services, which have been used around the world to this day, are now being used in a combined form in the healthcare services of many countries, and the possibility of integrating them is a widely discussed issue among researchers. It is noteworthy that no independent research has yet been published that has analyzed in detail how the influence of Chinese and other medical schools has been reflected in the development of Traditional Mongolian medicine. It is considered important to analyze this issue individually, in each direction, to clarify the historical process of how Traditional Mongolian medicine was formed today. Aim: Conduct research within specific codes in the works of Mongolian doctors to identify the presence of Chinese med ical data, knowledge, and information. Materials and Methods: The research was conducted using a qualitative research method based on historical and source books. Our study employed content and thematic analysis, utilizing coding and the identification of recurring patterns in the source text. Results: The results of the coding study show that most of the data used from Chinese meicines falls under the code “infection”. In Sumbe Khamba Ishbaljir’s sourcebook, 42.8% of the information was coded as infection, in Tsakhar Gevsh Luvsanchultemi’s sourcebook 50%, in Mindol Khutagt Jambalchoyjidanzanperenle’s sourcebook 47.05%, and in Ishdanzanvanjil’s “Shuren Chimeg” 87.5% was coded as infection. After that, when the information included in the code “injury” is classified by each sourcebooks, 33.3% is found in Ishbaljir’s sourcebook, 0% in Luvsanchultem, 24% in Min dol Khutagt Jambalchoyjidanzanperenley, and 6.25% in Ishdanzanvanjil, which ranks second among all codes. Conclusion 1. According to the research results, 56.66% of the Chinese medical information in the above works is related to in fection cases. 2. The integration of Chinese medicine learning with Traditional Mongolian medicine methods during epidemics such as “Bodoo” may be a major influencing factor that has shaped the current integrative medicine process.