Background: Effect of salbutamol nebulization in the treatment of acute bronchiolitis in infants is contraverse. Objectives: This study aims to evaluate effect of salbutamol nebulization in infants with bronchiolitis. Subjects and method: Patients were divided into two groups. Treatment group was given salbutamol nebulization with dose of 0.15mg/kg/time, with 2ml sodium 0.9%, 2 times with 30 minute interval and control group. Indicators including Sa02, heart rate and respiratory rate were measured before and after nebuliser of salbutamol. These indicators were compared at times before nebulizing (T1) and after 15 minute (T2), 30 minute (T3), 60 minute (T4). Clinical trends and mean treatment days were compared between two groups. Results: There were 80 infants under 1 year old with bronchiolitis studied from July 2004 to July 2005. Of whom, there were 53 (66.3%) male and 27 (33.7) female. Mean age was 5.4 \xb1 2.69 months. There were 59 infants with mild and moderate forms and 21 infants with severe one. There were 47 infants treated by salbutamol nebulization and 33 infants in the control group. No significant difference of clinical trends and avarage treatment days were found between two groups. Conclusion: Salbutamol nebulization showed no effect on the treatment of acute bronchiolitis in infants.
Bronchiolitis/ therapy ; Albuterol/ diagnostic use

We report here on the redistributed regional ventilation abnormalities after the administration of a bronchodilator and as seen on xenon-inhaled dual-energy CT in a patient with asthma. The improved ventilation seen in the right lower lobe and the decreased ventilation seen in the right middle lobe after the administration of a bronchodilator on xenon-inhaled dual-energy CT could explain a positive bronchodilator response on a pulmonary function test. These changes may reflect the heterogeneity of the airway responsiveness to a bronchodilator in patients with asthma.
Albuterol/*administration & dosage ; Asthma/*physiopathology/*radiography ; Bronchodilator Agents/*administration & dosage ; Child ; Female ; Humans ; Pulmonary Ventilation ; Radiation Dosage ; Tomography, X-Ray Computed/*methods ; Xenon/diagnostic use