Studies of the scalps from 42 patients with alopecia areala are given,using direct immunofluorescence ( DIP).Langerhans cells (LC)and T-lyrn hocytc subsets are observed.There is no significant difference between the number of OKT6 cells and Ia+ cells in the epidermis of all groups and the control.LC is seen in hair-bulb in many patients and most frequently in active stage.The main change of LC in hair follicle is increasing of T6+Ia- cells,not significant of T6+Ia+ cells.Most of the infiltrates around the hair follicles are T( OKT3+) cells.T4+cells number and T4/T8 ratio in active arc larger than in resting and recovering stages.DIF shows 88% of the patients having deposits of C3,IgG,and IgM.This suggests that alopecia areata may be the disorder of immnue associated with cellular and humoral immunity.

The aims of this study are to obtain a suilablc condition for the cardioplasty with the fundoplication and an observation of the effect of the antircflux function following the operations. The results show that a suppcrting dcvicc of a round tube with 1 - 1.2 ctn diamcter is used as a guide to establish a good lovver esophageal sphinctcr(LES). The experimental ani-mais may survive very long. The pressure in the sphimcter is cvenly the same as that after the operation immediately. The gastroesophageal reflux is never occurred except intragastric pres-sure is the same as or higher than LES. The lower csophagcal high pressure zone formed is similar to the smooth muscle in the lower part of csophagus at the sile of opcralions . The new formed cardia plays an excellent role of anturc flux function . This report suggists that the cardioplasty with fundoplication is useful for the treatment of esophageal achalasia and somc other abdpminal disorders.

Three crystals (Ⅰ, ⅡandⅢ) were isolated from Galeola shweliensis W.W. Sm. and identified by means of physical nd chemical properties, and spectral data. It shows that crystal I was a novel com-pound, named galeolate (CH3-(CH2)12-C-O-CH2 -(CH2)12-C-O-C-CH3). Crystal ⅡandⅢwere confirmed as steanc acid and ?-sitosterol, respectively. These three constituents were found inthis plant for the first time.

Serum concentrations of sialic acid, fucose, prealbumin(PA ), ?1-antitrypsin (?1-AT), ?1-acid glycoproteins(?1-AGP), haptoglobin (HP) and transferrin (TF) were measured in 94 nasopharyngeal carcinoma and 65 cancer of larynx. Statistical evalution was made with stepwise discriminant analysis, and the discriminant functions were obtained. The effectiveness of allocation were examined on every one of all patients in the original data, Our results suggested, with the discriminant function equation consisting of serum PA, ?1-AT, ?1-AGP, HP and TF concentrations we could best separate the patients sufferng from nasopharyngeal or laryngeal carcinoma from the normal; the effective rate of discriminant was 87.36% and 88% for nasopharyngeal carcinoma from normal and laryngeal carcin-oma from normal respectively. However using discriminant function equation,composed of serum sialic acid, PA and ?1-AT, we could also discriminate nasopharyngeal or laryngeal carcinoma with recurrence from the one with non-recurrence, the effective rate of discriminant was 93.1% and 80% for nasopharyngeal carcinoma and cancer of larynx respectively

In this paper, we reported the radiographic characteristics of arterio-portal shunt in 59 cases with hepatocellular carcinoma. All eases were arbitrarily divided into three types, the peripheral, central, and mixed. The angiographic manifestations of all types were described in detail with emphases on discusion of the mechanism of the pormation of arterio-portal shun, and the orientation of interventional approach. We suggested that active and solemn attitude should be taken but with different ways be considered rather than ignoring it, for obtaining the positive results.

Anti-HBs,HBeAg,Anti-HBcIgM weremeasured in 322 cases of HBsAgnegative hepatitis.It was foundthat 120 of which were positive forthose HBV infecting markres,indi-cating that the HBV infecting ratewas very high(37.3%)in HBsAgNegative hepatitis.The authorspointed out that for the diagnosisof HBV infection all the infectingmarkers mentioned above should beroutinely detected,especially forAnti-HBcIgM.

The influences of tbe two kinds ofserum on cryopreservation of lym-phocytes was examined with respectto the functional activities of therecovered cells,and highly reco-vered and viable cells were obtainedafter cryopreservation in the mediacontaining either human AB serumor new-born calf serum,The blastTransformation of the lymphocytesfrozen withAB serum was higherthan that with new-born calf serum,while(the new-born calf serum,wasof benefit to the stability of cellmembrane Secepeors and the forma-tion of rosettes.

TTH and DNP-BSA delayed hyper-sensitivity(DH)were transfered tononimmune human recipients withGoose derived transfer factor(TF-G)prepared from blood and spleen ofGoose immunized with TTH or DNP-BSA.Only human recipients injec—ted with immune TF-G showed DHskin reactivity by skin test.TTHDH response were only transferedby TTH specific TF-G but not DNPBSA specific TF-G and the DNP-BSAdermal reactivity could only be ob-served when DNP-BSA specific TF-G were employed.The fact that TF-G was able to tranfer donor specificDTH to human recipients suggestedthat there may be no absolute speciesbarriers for DTH transfer with TF.

In this paper,immunosuppression ofNK activity induced by(1)Human se-minal Plasma(HSP)and its Fraction-1 on sephadex G-100 in vitro;(2)in-travenous injection of HSP,Fraction-1 or mice sperm and(3)uptake of HSP,Fraction-1 or,mice sperm via rectalroute were studied.It has been pro-ved by our experiment that HSP,Fraction-1 and mice sperm possesspotent immunosuppressive effect interm of NK activity inhibition.Ascompared with intravenous injection,the immunosuppression induced byrectal exposure of HSP,Fraction-1or mice sperm is much stronger

Most of the luteinized unruptured follicle syndrome(LUFS)happens to women with menstrual disorders and is one of the important factors in "unexplained infertility". The mechanism of LUFS is still unknown. Using classic criteria, such as basal body temperature, serum progesterone, endomtrium biopsy and crystals of cervical mucous one can not distinguish the LUFS cycles from the ovulatory ones. There were low reports in our country in this aspect. In the reproductive endocrinology and infertility outpatient department we have found 2 cases of LUFS through ultrasound and laboratory findings. In this article, the pathophysiologic mechanism of this sydrome, its diagnostic method and index are discussed, and some problems concerning fertility and sterility are proposed.