1.A preliminary study on the incidence of cedar pollinosis in district of Wuhan
Lijuan XU ; Songyu ZHANG ; Qiang YANG ; Lei CHENG ; Min YIN ; Akira MIYOSHI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2000;(11):505-506
Objective:To investigate the incidence of cedar pollinosis in district of Wuhan. Method..A surveyrelative to cedar pollinosis was carried out in 309 students in Hubei Medical University in 1999,including ques-tionnaire investigation, nasal inspection and scratch test. From February to April of 2000,a clinical investigationof cedar pollinosis was adopted anong 205 patients of allergic rhinitis including scratch test and nasal mucosatest. Result:①The positive rate of cedar pollen scratch test of 309 students was 7.8%. ②59 cases (28.8%00) washypersensitive to cedar pollen clinically in allergen test. Conclusion : Cedar pollinosis is one kind of importantpollinosis in district of Wuhan and should be paid high attention to.
2.An infertile patient with Y chromosome b1/b3 deletion presenting with congenital bilateral absence of the vas deferens with normal spermatogenesis.
Shinnosuke KURODA ; Kimitsugu USUI ; Kohei MORI ; Kengo YASUDA ; Takuo ASAI ; Hiroyuki SANJO ; Hiroyuki YAKANAKA ; Teppei TAKESHIMA ; Takashi KAWAHARA ; Haruka HAMANOUE ; Yoshitake KATO ; Yasuhide MIYOSHI ; Hiroji UEMURA ; Akira IWASAKI ; Yasushi YUMURA
Clinical and Experimental Reproductive Medicine 2018;45(1):48-51
We report the case of a 46-year-old Chinese male patient who visited our clinic complaining of infertility. Semen analysis revealed azoospermia, and azoospermia factor c region partial deletion (b1/b3) was detected using Y chromosome microdeletion analysis. Testicular sperm extraction was performed after genetic counseling. The bilateral ductus deferens and a portion of the epididymis were absent, whereas the remaining epididymis was expanded. Motile intratesticular spermatozoa were successfully extracted from the seminiferous tubule. On histopathology, nearly complete spermatogenesis was confirmed in almost every seminiferous tubule. To our knowledge, this is the first case report of b1/b3 deletion with a congenital bilateral absence of the vas deferens and almost normal spermatogenesis.
Asian Continental Ancestry Group
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Azoospermia
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Epididymis
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Genetic Counseling
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Humans
;
Infertility
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Infertility, Male
;
Male
;
Middle Aged
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Semen Analysis
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Seminiferous Tubules
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Spermatogenesis*
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Spermatozoa
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Vas Deferens*
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Y Chromosome*
3.Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia.
Shinnosuke KURODA ; Takuya KONDO ; Kohei MORI ; Kengo YASUDA ; Takuo ASAI ; Hiroyuki SANJO ; Hiroyuki YAKANAKA ; Teppei TAKESHIMA ; Takashi KAWAHARA ; Yoshitake KATO ; Yasuhide MIYOSHI ; Hiroji UEMURA ; Akira IWASAKI ; Yasushi YUMURA
Clinical and Experimental Reproductive Medicine 2018;45(1):44-47
Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.
Adult
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Azoospermia*
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Fertility
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Fertility Preservation
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Humans
;
Infertility, Male
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Male
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Methods
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Microscopy
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Orchiectomy
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Scrotum
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Semen Analysis
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Seminiferous Tubules
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Sperm Injections, Intracytoplasmic
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Sperm Retrieval
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Spermatozoa*
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Testicular Neoplasms*
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Testis*
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Ultrasonography