Objective: To Study on the application of low temperature plasma sterilizer for endoscopic disinfection and cost, period of validity. Methods: Used duodenum mirrors were collected in December 2012-December 2013 in our department, respectively by low temperature plasma sterilizer with conventional disinfection sterilizer. To compare two methods of sterilization effect and cost, the period of validity. Results: Low temperature plasma sterilizer every time sterilization costs RMB (78.21+7.57), significantly higher than the conventional sterilizer (44.82 5.26) yuan (t=7.71, P<0.05);Low temperature plasma sterilizer sterilization is 5 to 7 months, longer than conventional sterilizer 9-28 d (t=12.50, P<0.05). Conclusion: Low-temperature plasma sterilization method has strong sterilization, temperature, rapid and long shelf life and other advantages, worthy of promotion and application.

Congenital cystic lung lesions are a group of congenital lung diseases with low incidence. These include congenital cystic adenomatoid malformation,bronchogenic cyst,congenital lobar emphysema and pulmonary sequestration. These malformations occur during the period of lung development stimulated by various factors. Manifestations of the diseases are very similar,but the pathogenesis and pathology are very different. Congenital cystic adenomatoid malformations are thought to be the results of the cessation of bronchiolar maturation with overgrowth of mesenchymal elements and without development of alveoli. There are 5 pathological types of congenital cystic adenomatoid malformations. Bronchogenic cysts are the results of abnormal budding from a segment of the tracheobronchial tree during embryo development,and the buds with no communication with normal tracheobronchial tree. Congenital lobar emphysema is a term reserved for hyperinflation of alveoli from idiopathic reasons or extrinsic compression,as well as pathological changes of the bronchial wall. Pulmonary sequestrations account for parts of nonfunctioning lung tissue that mostly do not communicate with normal bronchoalveolar tree and vascularized by a systemic artery,two types(intralobar and extralobar sequestration)are described.

Objective:To compare the immunology parameters and stress hormone in two groups of patients with lung cancer after radical operation and provide reference to clinical surgery.Methods:From March 2015 to March 2016, 72 cases in our hospital were accepted surgical treatment for lung cancer and divided into observation group and control group. Among them 36 cases of video-assisted thoracoscopy lung cancer radical surgery for the treatment of patients in mind as the observation group, 36 cases of open chest lung cancer radical operation were recorded as control group, respectively comparing two groups of patients with preoperative and postoperative 3 days red cell immune index, index of cellular immunity, stress hormone level and blood rheology index.Results:3 days after operation, the observation group in terms of RBC-C3b, RFER levels were significantly higher than those of control group and RBC-IC and RFER were significantly lower than those in the control group. 3 days after operation, the observation group CD3+, CD4+, CD3+CD4+ were significantly higher than those of the control group, while CD8+ was significantly lower than that of the control group. 3 days after operation, the observation group NE, Cor, angiotensin II (ANG II) was significantly higher than that of the control group (t=2.181,t=10.320,t=5.924;P<0.05). 3 days after operation in observation group, the plasma viscosity, erythrocyte sedimentation equation K value were significantly lower than those in the control group. The differences were statistically significant (t=29.698,t=7.411;P<0.05).Conclusion:The side-effect of thoracoscopy radical resection of lung cancer is small, and it has more advantages compared with open chest lung cancer radical operation.

Objective:To compare the adverse reactions for patients with brain tumor before and after gamma knife treatment, and analyze the application effect about pertinency nursing intervention measures.Methods: From January 2015 to February 2016, 80 patients with brain tumor who were treated by gamma knife were divided in observation group (40 cases, received pertinency nursing) and control group(40 cases, received normal nursing intervention) with random number table. And to compare the nursing effect difference between the two goups.Results: The average intracranial pressure of the two groups was (186.4±34.2)mmH2O before treatment; it was (232.3±41.5)mmH2O after treatment; and the difference was statistical significant (t=7.634,P=7.634). The observation group were lower than control group in epilepsy, scalp rupture and scalp infection rate, and the difference was statistical significant(x2=4.211,x2=5.541,x2=3.914;P<0.05). The average intracranial pressure and recovery time of observation group were (195.3±36.9)mm H2O and (13.4±3.2)d, respectively, after treatment. Both of the two indexes were lower than (218.2±42.5) mmH2O and (16.1±3.7)d of control group, and the difference was statistical significant(t=2.573, t=3.491;P<0.05). The observation group were lower than control group in occurrence rates of headache, vomiting and papilledema, and the difference were statistical significant (x2=4.114, x2=5.000,x2=4.211;P<0.05); the observation group was higher than control group for treatment satisfaction, and the difference was statistical significant (x2=5.165,P<0.05).Conclusion: The intracranial pressure of brain tumor patients will significantly rise after gamma knife treatment, and the pertinency nursing can reduce the occurrence rates of adverse reaction, intracranial pressure and symptom of encephaledema.

Objective: In order to have more direction to treat senile diseases,the feature of diseases and the principle of medication are investigated.Methods: Through combining the experiences of prevention and cure of senile diseases,we can conclude and analyze from its characteristics of imbalance of YIN and YANG,clumsy of reaction,deterioration of entrails,inclusion of excess and deficiency et al.Results: Aiming its physiological and pathological feature,we propose the standpoint that we should limit reinforcing and reducing,protect gastric-qi and prescribe containing minerals.Conclusion: It has evident specificity when we diagnose and prescribe for the aged,and can not equate that to the young.

AIM: To observe the anticonvulsant action of L-histidine in mice. METHODS: The anticonvulsant effect of L-histidine, and the antagonism of dl-chlorpheniramine to L-histidine were observed in convulsion mice induced by pentylenetetrazole (PTZ) and electric stimulation. RESULTS: L-histidine exerted remarkable anticonvulsant action with dose-response relationship in convulsion mice induced by pentylenetetrazole and electric stimulation, and the action was partly antagonized by dl-chlorpheniramine. CONCLUSION: L-histidine has anticonvulsant effect, and the action was partly antagonized by dl-chlorpheniramine, suggesting that L-histidine can pass the BBS and enter the central nervous system.

Objective To observe the changes in sublingual collateral vessels of elderly patients with diabetes. Methods Sublingual collateral vessels of 88 patients with diabetes were observed and compared with that of 76 normal people. Results The changes in sublingual collateral vessels of patients with diabetes were more serious than that of normal people (u=4.174, P

AIM: To compare the effects of histamine and its antagonists on tension of isolated rabbit basilar and mesenteric artery in vitro, and to observe the role of Ca 2+ in histamine induced response. METHODS: The dose response curves induced by histamine were recorded on the isolated rabbit central and peripheral arteries in different doses of diphenhydramine, cimitidine, and nifidipine. RESULTS: Histamine could cause contraction of basilar and mesenteric isolated arteries. Diphenhydramine and nifidipine antagonized these effects, while cimitidine enhanced this effect. CONCLUSION: There may be different receptors densities in different rabbit arteries; histamine shows the vasoconstrictive effect on both brain and mesenteric arteries; and the vasoconstrictive effect mainly produces via Ca 2+ inflax.

Objective To evaluate in a large open study if Jitongning capsule is potentially useful in the treatment of ankylosing spondylitis, and observe the safety of Jitongning capsule. Methods Sixty-five patients with ankylosing spondylitis were recruited. Jitongning capsule group were thirty-five patients, using Jitongning capsule at a dose of 4.2 g/d. The control group was using Sulfasalazine. There were thirty patients, using Sulfasalazine at a dose of 2.0 g/d. The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), the Bath Ankylosing Spondylitis Metrology Index (BASMI), patient’s global assessment, total body pain, spinal pain and night pain, ESR and CRP were measured at 1, 3, 6 months. The primary end point in this study was the proportion of patients with a 20% improvement response according to the ASAS International Working Group criteria (ASAS20 responders) at month 1, 3, 6. Results The study was completed on 56 patients. The treatment group was completed on 33 patients. The control group was completed on 23 patients. Side effects of two groups were uncommon and well tolerated. The ASAS20 was achieved by 66.67% of patients in the treatment group and by 60.86% of patients in the control group at month 6. Conclusion Jitongning capsule can treat the patients of earlier and mid-half ankylosing spondylitis. That is safety and similar to Sulfasalazine.

OBJECTIVE To investigate the mechanism and treatment of diabetes among elderly patients from the view of traditional Chinese medicine(TCM).METHODS On the basis of clinical experience and the achievement of the modern medicine,we expounded the mechanism of diabetes among elderly patients and treat from eight parts.RESULTS Using eight different TCM methods to treat diabetes elderly patients,we found their good curative effect with less adverse reaction,good prognosis,and very suit for old man.CONCLUSIONS TCM has large potentiality and advantage among diabetes elderly patients complicated with respiratory tract infection.