1.General Situation of Hospital Air Disinfection Research in China
Journal of Environment and Health 1989;0(06):-
Hospital air disinfection is the important countermeasure for the prevention and control of hospital infection. The researches on the technology and equipments of hospital air disinfection were reviewed and the research perspectives were presented in the present paper. In China, the methods of hospital air disinfection mainly include physical, chemical and cooperated disinfection methods. The hospital disinfection products are mainly the ultraviolet ray disinfector, the ozone disinfector and so on. The dynamic disinfection and the green disinfection are the important development direction in the hospital air disinfection field in China.
2.The Relationship between Decision-to-Delivery Interval in Emergency Caesarean Sections and Neonatal Outcome
Xia LI ; Aiqing HU ; Houwen PANG
Journal of Practical Obstetrics and Gynecology 2010;26(4):276-278
Objectlve:To assess the influential factors of decision-to-delivery inteval (DDI) in caesarean section, and its influence on neonatal outcomes.Methods:472 caesarean sections were divided into two groups according to Lucas's classification :the emergency caesarean sections as group 1 (291) ; and the e-lective caesarean sections as group 2 (181).It was divided into DDI ≤30 min group and DDI > 30 mir group in group 1.A retrospective study was performed in DDI, influential factors of DDI, neonatal Apgar score and umbilical arterial blood gas.Results: ①The mean DDI was 35.5±11.6 min in group 1,in wgich DDI≤30 min was 210 cases (72.2%) and 49.3 ±22.8 min in group 2, in which DDI≤30 min was 86 cases (47.5%).②IN group 1,umbilical artery pH and Apgar core at 1 min after birth could be improved sigbificantly in the cases of DDI ≤ 30 min (P<0.05) , but no correlation was found between the DDI and Apgar scrore at 5 min ,as compared with DDI >30MIN CASES(p>0.05).③It was mainly influenced by time taken to get the patient into operation room in DDI >30 min (56 cases, 69.1 %).Concluslons :The recommended DDI ≤30 min is not routinely achieved even in emergency caesarean sections.Shortening DDI as far as pos-sible might improve the neonatal outcome.
3.Role of β-endorphin in conA-induced spleen cell proliferation in rats with traumatic hemorrhagic shock
Aiqing WEN ; Liangming LIU ; Deyao HU
Journal of Third Military Medical University 2001;23(4):404-406
Objective To investigate the role of β-endorphin (β-EP) in conA-induced spleen cell proliferation after traumatic hemorrhagic shock. Methods ①Wistar rats with traumatic hemorrhagic shock were used and killed 0, 1, 3, 6,12 and 24 h after traumatic hemorrhagic shock. Plasma specimens were collected and β-EP levels in plasma were detected. Rats with sham-operation served as the control. ②Spleen cells isolated from normal rats were cultured in shock plasma (group Ⅰ), inactivated shock plasma (group Ⅱ) and shock plasma+β-EP antiserum (group Ⅲ) respectively. Con A-induced spleen cell proliferation was observed. Results ①The plasma β-EP level was elevated significantly immediately after shock, and reached the peak 1 h later, then showed a deceasing tendency and restored to the level as before shock at 24 h. ②Shock plasma remarkedly suppressed spleen cell response to the mitogen conA (P<0.01) compared with control; ConA-induced spleen cell proliferative function in group Ⅱ was significantly increased than that in group Ⅰ (P<0.01), so did in group Ⅲ, which still lower than in control. Conclusion The significantly elevated β-EP in the plasma after hemorrhagic shock might play an important role in inhibiting the proliferation of spleen cells.
4.Development and initial validation of Chinese version of multidimensional measure for recurrent abdominal pain scale
Fengxia WANG ; Min HAO ; Aiqing HU
Chinese Journal of Practical Nursing 2009;25(2):1-4
Objective To develop the Chinese version of multidimensional measure for recurrent ab-dominal pain scale(MM-RAP) and test the reliability and validity of it. Methods The Chinese version of MM-RAP was translated and revised and 100 children with recurrent abdominal pain and their parents were surveyed by it. Then the reliability and validity of the scale was tested. Results The teat-retest reliability coefficient of MM-RAP was 0.86. The total Cronbach's coefficient α of the scale was 0.80. Cronbach's coef-ficient α of each dimensions was above 0.70. The results of correlation analysis showed that there was higher correlation between items and its belonged dimensions than that with other dimensions. The results of confir-matory factor analysis indicated the factor structure was similar with the theoretical construction of the in-strument. Conclusions The Chinese version of MM-RAP demonstrated good reliability and validity and was an effective assessment instrument for measuring recurrent abdominal pain of Chinese children.
5.Association between the GGN tri-nucleotide repeat polymorphism in androgen receptor gene and prostate cancer risk:a systematic review and meta-analysis
Aiqing YU ; Xiaowen YANG ; Pei HU ; Shirong YAN
International Journal of Laboratory Medicine 2014;(17):2293-2295
Objective To provide a powerful and conclusive result for the association between the GGN polymorphic repeats in androgen receptor (AR)gene and prostate cancer (PCa)risk.Methods CNKI,VIP,Wanfang,PubMed/Medline,Embase and The Cochrance Library electronic database were used to retrieve the eligible publications addressing the association between the AR gene GGN polymorphic repeats and prostate cancer risk.16 GGN polymorphism repeats were used as cut off value,meta-analysis was ap-plied to the study on the association between the length of polymorphism repeats and prostate cancer risk.Results 9 cases of con-trol studies were included in this meta-analysis and a total of 2 438 cases and 1 968 controls were included.People with ≤16 GGN polymorphism repeats displayed a higher risk of prostate cancer(OR =1.15,95%CI :1.00 -1.31,P =0.04).Conclusion ≤16 GGN polymorphism repeats polymorphism associated with increased risk of prostate cancer.
6.The influence of passive smoking during pregnancy on the ability of cognitive and behavior of attention-deficit hyperactivity disorder children
Aiqing HU ; Fengxia WANG ; Min HAO ; Yuanyuan LI
Chinese Journal of Primary Medicine and Pharmacy 2010;17(6):744-747
Objective To investigate the influence of passive smoking during pregnancy on the ability of cognitive and behavior of attention-deficit hyperactivity disorder (ADHD) children. Methods 92 ADHD children with passive smoking during pregnancy,99 cases without passive smoking and 100 cases normal children were selected. Their abilities of cognitive and behavioral were evaluated by intelligence test, Wisconsin card sorting test and Stroop test. Results The verbal intelligence quotient ( VIQ), performances intelligence quotient (PIQ) and the full intelligence quotient (FIQ) of ADHD children were significantly lower than normal children, especially for the ADHD children with passive smoking during pregnancy. Compared to the normal children,the ADHD children showed significant difference in the time of reading card A, B,C and reading errors of card B,C,especially for the ADHD children with passive smoking during pregnancy. Compared to the normal children, the ADHD children showed significantly more in the scores of responses errors, perseverant responses, perseverant errors, perseverant errors percentage and non-perseverant errors, and lower in conceptualization plane, especially for the ADHD children with passive smoking during pregnancy. Conclusion The defect of the ability of cognitive and behavior of attention-deficit hyperactivity disorder children were the worse for passive smoking during pregnancy.
7.A Study on Interpersonal Forgive and Revenge of Undergraduates
Sanman HU ; Aiqing ZHANG ; Yanjie JA ; Ha ZHONG
Chinese Journal of Clinical Psychology 1993;0(01):-
Objective: To explore the relationship between interpersonal forgiveness and revenge and some influential factors in college students. Methods: Rumination Scale,Empathy Scale, Tendency to Forgive Scale and Revenge Motivation Scale were administered to 194 college students. Results and Conclusion: ① There were significant gender differences in the degree of seeking revenge and rumination. ② Most of interpersonal transgression indeed happened between fellow students. ③ Correlation analysis showed significantly negative correlation between forgiving and hurtfulness, revenge motivations, rumination, and between revenging and tendency to forgive, empathy; and positive correlation between forgiving and empathy and between revenging and revenge motivation, hurtfulness. Further regression analysis revealed that revenge motivations, rumination and empathy were significant negative predictors of forgiving; hurtfulness and revenge motivations were significant positive predictors of revenging.
8.Role of ?-endorphin in the suppression of cellular immunity of rats following trauma-hemorrhagic shock
Aiqing WEN ; Jun WANG ; Deyao HU ; Liangmin LIU
Chinese Journal of Pathophysiology 1986;0(01):-
AIM: To explore the role of plasma ?-endorphin(?-EP) in the suppression of cellular immunity following trauma-hemorrhagic shock(T-HS). METHODS: ① Wistar rats with T-HS were sacrificed at 0 h, 1 h, 3 h, 6 h, 12 h, 24 h after T-HS. Plasma sample was collected and ?-EP levels in plasma was measured. Rats with sham-operated were served as the controls. ②In in vitro experiment, splenic cells were isolated and mixed from four normal rats and cocultured with shock plasma (SP) or SP +?-EP antiserum. ConA-induced splenic cell proliferation, IL-2 production, IL-2R expression were examined. RESULTS: ① Levels of plasma ?-EP elevated remarkably after T-HS immediately, peaked at 1h , showed decreasing tendency and restored normal 24 h after T-HS. ② Shock plasma significantly suppressed ConA-induced splenic cell function. Levels of plasma ?-EP were negatively correlated with spenic cell proliferation and IL-2 production and IL-2R expression. Compared with SP group, splenic cell function elevated markedly in SP + ?-EP antiserum group, but still lower than that in controls. CONCLUSION: The elevated plasma ?-EP following T-HS was involved in the suppression of cellular immunity.
9.Changes of coagulation and lung injury in response to leukocytapheresis in endotoxemia dog
Shungang ZHOU ; Zhigao HE ; Xiankai HUANG ; Aiqing WEN ; Jing HE ; Bo HU ; Fangxiang CHEN
Chinese Journal of Trauma 2011;27(3):264-269
Objective To observe the effect of leukocytapheresis(LCAP)on the coagulation,fibrinolysis system and lung injury in the endotoxemia dog and explore the mechanism in the endotoxin-induced lung injury dog. Methods Endotoxemia-induced model in dogs was established by administration of lipopolysaccharide(LPS,2 mg/kg).Separation of the leucocytes wag performed with the automated continuous flow blood cell separators.A total of 30 male mongrel dogs were randomly divided into LPS group(group L,only injected with LPS,with no LCAP),sham LCAP group(group S,received sham LCAP at 12-14 hours after administration of LPS)and LCAP treatment group(group T,received LCAP at 12-14 hours after administration of LPS),10 dogs per group.The dynamic changes of the activated protein C(APC),soluble thrombomodulin and plagminogen activator inhibitor-1 in the serum were measured at 0 hour before LPS administration,at 2,6,12,14,16,24 and 36 hours after administration of LPS.Results Through LCAP,there found the following four results:(1) the APC level in the serum of the group T wag(50.805±4.422)μg/ml and(40.480±2.993)μg/ml at 14 hours and 16 hours respectively,which were significantly higher than(45.881±4.024)μml and(35.935±4.057)μg/ml in the group L(P<0.05).(2)The expressions of soluble thrombomadulin in the group T was (9.688±O.914)μml and(10.492±O.865)μg/ml at 14 hours and 16 hours respectively,which was statistically lower than(11.005±0.854)μg/ml and(12.04±0.954)ug/ml in the group L(P<0.05).(3)Thelevel of plagminogen activatorinhibitor-1 in the group T was lower than that in the group the group T Wag statistically lower than that in the group L(ALI/ARDS occurred in 2 and 7 dogs of the groups T and L respectively within 36 hours after infusion of LPS.P<0.05). Conclusions At the decrease the incidence of acute lung injury partly due to its role in improving the function of coagulation and fibrinolysis.
10.Human urate transporter 1 promoter polymorphisms and hyperuricemia in Chinese Han people
Lin HAN ; Qing YU ; Dongming HU ; Teng ZHOU ; Aiqing ZHANG ; Changgu LI
Chinese Journal of Endocrinology and Metabolism 2012;28(1):36-39
ObjectiveTo analyze the association of human urate transporter 1 ( hURAT1 ) gene promoter single-nucleotide polymorphisms(SNPs) with primary hyperuricemia ( HUA ) in Chinese Han people.MethodsA total of 215 patients with HUA and 323 healthy subjects were chosen to be investigated of SNP of hURAT1 promoter by PCR and sequencing.ResultsFive SNPs were identified,including-454A/T,-434T/C,-382C/T,-87C/T,and + 118G/A.Pairwise linkage disequilibrium analysis displayed a high linkage disequilibrium between the five SNPs ( r2 =0.99).In HUA group,the heterozygous genotypos ( AT,CT,CT,CT,AG ) frequencies were significantly lower than those in control group ( P<0.05 ).Logistic regression analysis showed that the heterozygosis genotypes ( AT,CT,CT,CT,AG) were protective factors of HUA ( OR 0.68-0.75 ).The minor allele ( T,C,T,T,A ) frequencies for both SNPs were significantly different between two groups ( P =0.022,P =0.038 ).ConclusionThese findings indicate that -454A/T,-434T/C,-382C/T,-87C/T,and + 118G/A SNPs of hURAT1 gene promoter area are associated with HUA in Chinese Han population.