1.Microporous polysaccharide hemospheres reduce blood loss in total hip arthroplasty
Tiansheng LIU ; Qi WANG ; Hao WANG ; Aipeng LIU ; Jinchao MA
Chinese Journal of Tissue Engineering Research 2015;(12):1872-1877
BACKGROUND:In foreign animal experiments and clinical reports, microporous polysaccharide hemospheres are characterized as good hemostatic effect, no delayed bleeding, good biocompatibility, and no adverse reactions in the body. OBJECTIVE:To assess the efficacy and safety of microporous polysaccharide hemospheres on reducing blood loss after unilateral total hip arthroplasty. METHODS:Totaly 98 patients who received unilateral total hip arthroplasty due to femoral neck fractures, 39 males and 59 females, aged 61-77 years, were randomly divided into two groups: test group, treated with 1g microporous polysaccharide hemospheres before suture of wound; control group, treated with electric coagulation hemostasis before suturing. Drainage tubes were placed in the two groups. Hemoglobin, blood loss, alogeneic transfusion rate, drainage volume, coagulation index and incidence of deep venous thrombosis of the lower limbs were compared. RESULTS AND CONCLUSION:The total blood loss, drainage volume, and transfusion rate in the test group were significantly lower than those in the control group (P < 0.01), but there were no differences in D-dimer, platelet count, activated partial thromboplastin time and international normalized ratio between the two groups. One case of each group developed deep venous thrombosis of the lower limbs, and no significant difference was in the incidence of deep venous thrombosis between the two groups. No infection occurred. These findings indicate that microporous polysaccharide hemospheres that are safe, effective and convenient can reduce the visible and hidden blood loss after unilateral total hip arthroplasty.
2.Effect of patients' participating supervision on nurses' compliance to hand hygiene
Ying LIU ; Xiang ZHANG ; Yuan FENG ; Min SHI ; Lili LIU ; Aipeng WANG
Chinese Journal of Infection Control 2017;16(4):307-309,313
Objective To evaluate the effect of patients' participating supervision on improving nurses' compliance to hand hygiene(HH) in intensive care unit(ICU).Methods Implementation of HH of ICU nurses was investigated by field observation and investigation of patients, intervention measures were began to be implemented in February 2016, HH compliance among ICU nurses after(February-May 2016) and before (November 2015-January 2016) intervention was compared.Results A total of 81 patients were included in the study, 38 were in pre-intervention group and 43 were in post-intervention group.52.63%(20/38)in pre-intervention group and 88.37%(38/43)in post-intervention group seen, heard or recalled that nurses had performed HH, difference was significant(X2=12.67, P<0.005);after intervention, HH rates before and after touching a patient, before aseptic procedure, and after touching patient surroundings were all higher than before intervention (all P<0.01).Conclusion Patients' participation in improving HH compliance of ICU nurses is feasible, and it is worth to be popularized.
3.Application of matrix assisted laser desorption/ionization time-of-flight mass spectrometry on high-risk human papillomvirus detection in clinic
Shuang YU ; Aipeng ZHANG ; Yali LI ; Wei WANG ; Jingfing LI ; Yang GAO ; Ling YANG ; Yu LIANG ; Caiyun LI ; Jian WANG
Chinese Journal of Laboratory Medicine 2009;32(9):1006-1010
clinical applications, especially suitable for large-scale cervical screening and epidemiology investigation.