Objectives: 1) To translate and cross-culturally adapt the Knee Injury and Osteoarthritis Outcome Score (KOOS) into Filipino; 2) To validate the Filipino translation of KOOS using the Filipino Short-Form 36 Health Survey (SF-36) among patients with knee osteoarthritis (kOA) at a tertiary hospital. Methodology: A Filipino version of the KOOS was translated and cross-culturally adapted from the original English version and validated following standard guidelines. Adult Fiipino patients with knee osteoarthritis at the University of the Phiippines-Philippine General Hospital were asked to complete identical questionnaires containing the Filipino KOOS and Filipino SF-36, with re-test on the same patients after a median of 14 days. Reliability was assessed using Cronbach’s alpha and intraclass correlation coefficients (ICC); dimensionality using convergent and divergent construct validity. Results: The Filipino translation of the KOOS was administered to 30 patients with knee OA (kOA). Cronbach's α across the Filipino KOOS domains ranged from 0.71 to 0.89 suggesting good internal consistency. The reproducibility of measurements of all KOOS subscales by ICC ranged from 0.97 to 1.0. For convergent construct validity, there was moderate correlation between KOOS ADL (0.38, p =0.03) and knee-related QoL (0.42, p=0.02) by SF-36 Physical Functioning (PF). A strong correlation (0.51, p=0.003) was observed between KOOS sports and recreation domain with SF-36 PF. For divergent construct validity, there was weak correlation between KOOS pain (0.015, p=0.93) and symptoms (0.15, p=0.42) with SF 36 Social Functioning. Conclusion The Filipino version of the KOOS is a valid and reliable instrument to measure the different aspects of disability affecting quality of life of Filipino patients with kOA.
Osteoarthritis, Knee ; Knee Injuries

BACKGROUND

COVID-19 pandemic led to a dramatic loss of human life worldwide and presented an unprecedented challenge to public health. One of the solutions in addressing the problem was mass vaccination in order to attain herd immunity. However, most people were hesitant to be vaccinated particularly due to their fear of the adverse events; hence the goal of this study was to determine the possible adverse events (AEs) experienced during administration of CoronaVac^TM COVID-19 Vaccine.

The objective of the study was to monitorthe occurrence of adverse events within one hour, two to 24 hours, and 25 to 72 hours after administration of the first and second dose of CoronaVac^TM COVID-19 Vaccine in a tertiary government hospital in Pangasinan.

This cross-sectional study was done from February to April 2021 at Region 1 Medical Center. Employees who received the two doses of Sinovac-CoronaVac^TM vaccine and gave their informed consent were included in the study. Participants were monitored closely for adverse events within 30 minutes following administration of the vaccine and were instructed to report any local and systemic AEs to the Hospital Epidemiology Center Office. Individuals were also followed up through telephone to investigate the occurrence of any complaints after 24 to 72 hours.

A total of 353 participants who received the complete doses of CoronaVac^TM were included in the study. The incidence of AEs was higher after the first dose compared with the second dose. After the first dose of CoronaVac^TM 12.5% reported AEs after the 1st hour, 14.2% two to 24 hours after the vaccine, and 1.4% on the 25^th hour up to the 72^nd hour. Pain on injection site was the most common adverse event during the first hour (8.2%). On the 2nd hour up to 24 hours, headache, and myalgia (14.2%) were more evident. Headache was reported in 1.1% of the participants after 25-72 hours of vaccination. After the second dose, only one participant reported multiple AEs such as fatigue, headache, rash and retroorbital pain (1, 0.7%).

In this study, 28.1% of the participants experienced adverse events afterthe first dose of CoronaVac^TM vaccine. AEs were higher after the first dose (28.1%) compared with the second dose (0.3%). Injection site pain was the most common adverse event during the first hour, then headache and myalgia during the 2^nd hour up to 24 hours, and headache on the 25^th – 72^nd hour after vaccination. Only one participant reported several AEs after the 2^nd dose of the vaccine.

Introduction: The Coronavirus disease 2019 (COVID-19) is a major health crisis that affected 32 million people to date and caused death to 990,000 individuals. The impact of this pandemic on the healthcare system took its toll especially to the healthcare workers and its effect on their physical and mental health. We aim to assess severity of generalized anxiety, depression and subjective distress among medical, allied and ancillary healthcare workers (HCWs) who handled COVID-19 patients. Methodology: This is a cross sectional, survey-based study done from July 1 to August 31, 2020 involving healthcare workers who handled COVID-19 patients in a tertiary hospital in Pangasinan. The self-administered questionnaires used were the Generalized Anxiety Disorder- 7 for generalized anxiety, Patient Health Questionnaire (PHQ-9) for depression and Impact of Events Scale–Revised (IES-R) for subjective distress. Results: A total of 417 of 450 contacted individuals completed the survey, with a participation rate of 92.67%. Majority were women (64.57%) and 53.24% were aged 19 to 30 years old. Sixty percent of the respondents were nurses, 25.9% were physicians and the rest were composed of medical technologists (6.47%), radiologic technologists (5.52%) and respiratory therapists (1.68%). Subjective distress was noted to be present in 253 (60.67%) healthcare workers followed by anxiety 224 (53.72%) and depression 184 (44.12%). Allied health professionals and male participants experienced anxiety the most as well as subjective distress. Depression was more severe among physicians (2 [1.85%]) and women (3 [1.1%]). Physicians and allied health professionals reported more severe degrees of mental health symptoms compared to nurses. Conclusion In this study, the proportion of HCWs who experienced subjective distress, generalized anxiety and depression were 60.67%, 53.72% and 44.12% respectively. Generalized anxiety and subjective distress were more severe in men and allied health professionals. Meanwhile, the more severe symptoms of depression were present in women and among physicians.
COVID-19 ; Coronavirus ; Depression ; Anxiety ; Mental Health ; Health Personnel