1.Classification survey requirements of continuity care service in puerperium and the analysis of related factors
Xiaohong LIN ; Yufang WANG ; Yu YE ; Xiaoyan LIU ; Aimei QIN ; Yuqiong WANG
Chinese Journal of Practical Nursing 2015;31(33):2527-2530
Objective To understand the continuous care needs and related services will of the women in puerperium, and analyze the relative factors of the continuity care of those discharged from maternity hospital.Methods A total of 207 delivery women who were discharged from a hospital in Chenghua District Maternal & Child Care Center in Chengdu city from September to December, 2014 were investigated with self-made questionnaires.Results As for newborn babies' continuity care service, what those delivery women care most were newborn babies' common disease prevention and care, and as for their own continuity care service, what they most need were maternal uterine instauration care.Enforcers for continuity of care services were more inclined to obstetricians and pediatricians, and the service forms tended to make telephone calls or do follow-up visits.Time frequency of the follow-up visits was inclined to 7 days once.Delivery women's educational degree (r=-0.216, P<0.01), place of residence (r=0.208, P<0.01), whether they would participate in pregnant Women school (r=0.192, P<0.01), pregnant women school number (r=-0.382, P<0.01),the newborn's tire(r=0.173, P<0.05) and maternal type(r=0.161, P<0.05) were factors that influenced the degree of maternal continued care needs.Conclusions The main factors which influence the continuity care in obstetrics are educational degrees, place of residence and the types of delivery women.As a result, different methods of continuity care service should be established to aim at different groups of people so as to promote the service quality in obstetrics in general to meet the needs of delivery women at all levels.
2.Preventive effect of exogenous hydrogen sulfide on hepatic fibrosis in rats.
Qinhai SHEN ; Zhaomin QIN ; Aimei LU
Journal of Central South University(Medical Sciences) 2012;37(9):911-915
OBJECTIVE:
To determine the effect of exogenous hydrogen sulfide on experimental hepatic fibrosis in rats and its mechanism.
METHODS:
Wistar male rats were randomly divided into three groups: a normal control group (n=8), a model group (n=8), and a hydrogen sulfide prevention group (n=8). The rat model of hepatic fibrosis was reduced by intraperitoneal injection of carbon tetrachloride (CCl4). The prevention group, in addition to intraperitoneal injection of 40% CCl4, was intraperitoneally administered H2S once a day until 8th week. After the experiment, the liver function and liver fibrosis were assayed. Liver tissue samples were used for histopathological changes. The expression of TGF-β1 in liver tissue was detected by RT-PCR and Western blot.
RESULTS:
Compared with the model group, the levels of ALT, AST, HA, LN, and PC III in the sulfide group were significantly reduced (P<0.01 or P<0.05), ALB content was increased (P<0.05) in the serum, TGF-β1 expression was obviously reduced, and the degree of liver fibrosis was improved (P<0.05).
CONCLUSION
Exogenous hydrogen sulfide can effectively inhibit the development of hepatic fibrosis, reduce the expression of TGF-β1, and decrease the the sediment of extracellular matrix in the liver tissues.
Animals
;
Carbon Tetrachloride
;
Extracellular Matrix
;
metabolism
;
Hydrogen Sulfide
;
pharmacology
;
therapeutic use
;
Liver
;
pathology
;
Liver Cirrhosis
;
chemically induced
;
pathology
;
prevention & control
;
Male
;
Rats
;
Rats, Wistar
;
Transforming Growth Factor beta1
;
antagonists & inhibitors
;
metabolism