Objective: Through analyzing a fault case for GE P5 Color Doppler Ultrasound to find out the main performance and effect of computer failure in Medical devices fault and the solution for failure. Methods: By consulting with maintenance manuals and relevant information, and combining with the main problems of the computer equipment to make detailed analysis, and then discussed and explored the solution for resolving problem. Results: By using the elimination method of relevant calculating fault, computer system failure of Color Doppler Ultrasound can be effectively eliminated, and the normal operation of equipment can be guaranteed. Conclusion:With the rapid development of computer technology, it is applied wider and wider in the modern medical instrument and has become an important support technology of many medical equipment, and has been inseparable with medical equipment's technology development. Therefore, many computer failure of software and hardware directly become medical equipment failure, even directly affects the normal work of medical devices. Consequently, in the maintenance and repair for medical equipments, maintenance and repair of computer system becomes particularly important, and has been an important part to guarantee the normal work of medical equipment. We should pay more attention to it in work practice.