3.Influence of Oral Antigens on Expression of Costimulatory Molecules CD80/CD86 on Surface of M?
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(12):-
Objective To study the influence of oral antigens on the expression of costimulatory molecules CD80/CD86 on the surface of M and to investigate the genesis of pregnancy immunological tolerance induced by oral antigens through CD80/CD86. Methods Mice of spontaneous abortion(CBA/J?DBA/2) were divided into two groups: immune group and non-immune group.Trophoblast membrane antigen-2(TMA2)or ovum albumin(OVA) was administered orally to the mice in the immune group.Mice of normal pregnancy(CBA/J?BALB/c) were served as controls.The number of CD80/CD86 M of spleen and mesenteric lymph node(MLN) were determined by double-label FCM method. Results In the MLN,CD80 M of non-immune group was increased significantly as compared with that of the control group(P
4.Experience of Professor LIU Zhe for Treating Essential Tremor with Acupuncture
Journal of Zhejiang Chinese Medical University 2017;41(2):162-164
[Objective]To study the clinical experience of Professor LIU Zhe treatment of essential tremor with acupuncture.[Methods]The paper states Professor LIU's understanding of treating essential tremor from the pathogenesis, acupuncture points and acupuncture manipulations, then summarizes the principle, regularity, and the features of acupuncture manipulations for Professor LIU treating essential tremor of different types of syndrome, so as to elaborate the clinical experience of Professor LIU. [Result] Professor LIU Zhe considers the age-dependent deficiency of qi and blood and insufficient liver and kidney syndrome to be a common one of essential tremor, as an experienced doctor, he distinguishes different types of syndrome from sign, tongue, pulse and so on. He places great emphasis on nourishing the bone marrow and tonifying liver and kidney. According to the symptoms select acupuncture points with the effects of nourishing the bone marrow and calming the liver to stop the wind, tonifying liver and kidney and supplementing qi and nourishing blood. Professor Liu sets a high value on selecting points of head and makes use of the point of Fengchi with unique acupuncture manipulations to relax cerebrovascular. In clinically, the curative effects are remarkable. [Conclusion]The unique method for treating essential tremor of Professor LIU gives some inspirations for clinic. It is worth of a deep study and spreading.
5.Clinical characters of pulmonary thromb-embolism in ≥70 elderly patients
Haimei QI ; Bing LIU ; Hu AI ;
Chinese Journal of Geriatrics 2000;0(04):-
Objective To explore the clinical characteristics and effects of thrombolytic and anti coagulation treatment in over 70 year old patients with pulmonary thromb embolism(PTE). Methods The clinical findings, diagnostic techniques, effects of thrombolytic therapy and anti coagulation in 58 over 70 year old patients with PTE were analyzed retrospectively. Results Deep venous thrombosis (DVT) in lower limbs (74 1%) was the most common thrombolism prone factors in our study. Limitation of movement and long term stay in bed due to a variety of causes were in the next place. The clinical findings were atypical, associated with a false diagnostic ratio of 46 5% in elderly patients with PTE. Undefined causal and different degree of dyspnea along with sudden and persistent hypoxemia were the main characteristics. Spiral CT and radioactive nuclear ventilation perfusion scan were important methods for diagnosis of PTE with positive finding of 95 7% and 62 5%, respectively. The effective and cure rate of thrombolytic therapy combined with anti coagulation, anti coagulation and anti platelet therapy was 91 3%, 75 8%, 0 and 47 8%, 17 2%, 0, respectively. Conclusions The most common risk factors of PTE in the elderly was DVT and the long term stay in bed or stay without active moving. The clinical symptoms were not only atypical but also variable. Thrombolytic with anti coagulation therapy is safe and effective, but anti platelet coagulation alone is not benefit.
7.The platelet characteristics of 22q11 microdeletion and its clinical application
Xicheng DENG ; Qi AI ; Zhiping TAN ; Pingbo LIU ; Erjia HUANG
Journal of Chinese Physician 2013;15(10):1327-1329
Objective 22q11 microdeletion is featured with hemotological dysfunction,among others:hypocalcemia,thrombocytopenia and megathrombocyte.This study was trying to work out the platelet characteristics of 22q1 1 microdeletion patients and its potential clinical application.Methods A total of 80 cases who had undergone open-heart surgery were selected and confirmed with fluorescence in situ hybridization (FISH) to have 22q1 1 microdeletion among 40 cases while the others were negative.The relevant data in full blood routine of all the 80 cases in hospital information system (HIS) then were collected and analyzed with suitable statistical methods.Results The mean platelet volume in microdeletion group was statistically higher than that in the control group [(11.20 ± 1.94)fL vs (8.95 ± 1.58) fL,P <0.01].The area under the receiver operating characteristic (ROC) curve was 0.82,meaning significant predictive values.The corresponding sensitivity and specificity for mean platelet volume (MPV) =10 fL were 70.0 % and 80.0 %,respectively.Conclusions MPV in congenital heart defect patients with 22q11 is significantly higher than those without 22q11.It is an effective method for preliminary screening 22q11.Being obtained from full blood routine data,it is economic and quick.MPV =10 fL can be used as a cutoff for guidance for irradiated blood transfusion postoperatively.
8.Initial stress distribution of the maxillary anterior teeth, periodontal ligament and alveolar bone by different intruding loadings A three-dimensional finite element analysis
Hongfei LU ; Zhihui MAI ; Qi CHEN ; Yue CHEN ; Hong AI
Chinese Journal of Tissue Engineering Research 2011;15(48):8964-8967
BACKGROUND: It is very important to explore an optimal loading force that can both allow effective intrusion and cause no damage to the teeth.OBJECTIVE: To investigate the optimal loading conditions, including loading force values and directions, in the intruding mechanics of maxillary anterior teeth.METHODS: A three-dimensional finite element model (3D FEM) of the maxillary anterior teeth was constructed to include the periodontal ligament (PDL), alveolar bone, and appliance (brackets and wire). The initial stress distribution and force of the maxillary anterior teeth were analyzed when the 3D FEM was loaded with different intruding force values and directions. RESULTS AND CONCLUSION: The optimal value of the intruding force for 6 anterior teeth fell within the range from 0.5 N to 1.0 N. The maximum stress was detected at the distal cervical level of the lateral incisor, and a relatively even distribution of initial stress was observed at 20° palatal deviation to the Y axis. The results suggest that using mini-screw implants at the labial region between the canine and lateral incisor and a combined 0.5-1.0 N intruding force with a distal force could be an optimal intrusion force system by which patients with normal occlusion could obtain a pure intrusion of anterior teeth.
9.Risk factors for cognitive impairment after ischemic stroke
Yu ZHU ; Xinxin QI ; Yan WANG ; Qinglong AI
International Journal of Cerebrovascular Diseases 2012;20(3):232-236
Early diagnosis and early intervention for cognitive impairment after ischemic stroke can delay disease progression and prevent the occurrence of dementia.This article reviews the advances in research on ischemic stroke caused each risk factor for cognitive impairment.
10.Cephalometric analysis for Angle's class Ⅲ malocclusion patient with maxillary front traction
Hongfei LU ; Zhihui MAI ; Hong AI ; Qi CHEN
Chinese Journal of Medical Aesthetics and Cosmetology 2009;15(6):395-398
Objectives To study the changes of hard tissue before and after orthodontic treatment for Angle's class Ⅲ malocclusion adolescence patient with maxillary front traction. Methods 20 cases of Angle's class Ⅲ malocclusion adolescence patients were treated by front traction in maxilla, while there were 20 cases of Angle's class Ⅰ malocclusion adolescence patients as the control group. Cephalometric a-nalysis was carried out before and after the treatment. Data were analyzed by SPSS11.0 system using paired t-test. Results There were significant increases in the length, anteroposterior diameter and thick-ness of maxillary sinus (P<0.05), while there was no significant differences in the site and central point of maxillary sinus(P>0.05). Conclusions It is a effective approach to change the hard tissue after ortho-dontic treatment for Angle's class Ⅲ malocclusion adolescence patient with front traction in maxillary area.