1.Discrepancy in blood pressure between the left and right arms - importance of clinical diagnosis and role of radiological imaging
Pei Xuan Kuan ; Pui Wen Tan ; Ahmad Tirmizi Jobli ; Norsila Abd Razak
The Medical Journal of Malaysia 2016;71(4):206-208
Introduction: Differences in systolic blood pressure reading
between arms are common but could signal trouble if the
discrepancy is significant. Early detection of aortic
dissection could invariably determine patient’s survivability.
Hence, a high index of suspicion with prompt diagnostic
imaging is vital for accurate diagnosis. Case Presentation: A
previously healthy 35-year-old lady was referred from
district hospital for hypertensive cardiomyopathy
complicated by acute pulmonary oedema. After being
admitted to the Intensive Care Unit, the mean arterial
pressure on the left arm was noted to be significant higher.
On physical examination, both lower limbs were dusky in
appearance because of poor perfusion. Investigations:
Computed Tomography Angiography showed extensive
arch and abdominal aorta dissection extending to the
proximal common carotid artery. There was distal abdominal
aorta thrombosis with partial left renal infarction.
Echocardiogram showed global hypokinesia, presence of
intimal flap, aortic regurgitation and mild pericardial
effusion. Supine chest X-ray showed apparent
cardiomegaly. Treatment: Repair of the ascending aortic
dissection and suspension of the aortic valve by the
cardiothoracic team on Day 2 of admission. The vascular
team did bilateral high above knee amputation on Day 9 of
admission. Outcome: Patient passed away on Day 10 of
admission. Discussion: With the absence of classical
features of aortic dissection, establishing the diagnosis can
be challenging and requires both good clinical judgment
and prompt radiological imaging, such that early treatment
can be initiated. Conclusion: A high index of suspicion and
good clinical judgment is needed in cases of significant
blood pressure discrepancy between arms.
Blood Pressure
2.Myxopapillary ependymoma of cauda equina presented with communicating hydrocephalus and papilloedema: A case report
Ting Siew Leng ; Ahmad Tirmizi Jobli ; Sim Sze Kiat ; Dayangku Norlida Awang Ojep
The Medical Journal of Malaysia 2019;74(4):338-340
We reported a case of cauda equina myxopapillary
ependymoma in a patient who presented with atypical
history of progressive blurring of vision. Ophthalmology
examination revealed relative afferent pupillary defect,
binasal hemianopia and papilloedema. This case report
serves as a reminder that the intraspinal tumour could be a
cause of papilloedema, despite rare, should be considered
in a hydrocephalus patient who presented with no
intracranial pathology and minimal spinal symptoms.
3.Delayed diagnosis and treatment of rheumatoid arthritis in Sarawak General Hospital
Sharifah Aishah Wan ; Cheng Lay Teh ; Yaw Kiet Cheong ; Ahmad Tirmizi Jobli
The Medical Journal of Malaysia 2020;75(2):141-145
Introduction: Rheumatoid arthritis (RA) is an autoimmune
systemic inflammatory disorder characterised by
symmetrical polyarthritis which leads to damage of joints if
untreated. Early diagnosis and treatment of RA to achieve
tight control of the disease will improve outcome and
prevent disability.
Objective: We aimed to examine the delays in the diagnosis
of RA in patients presenting to the Rheumatology Unit,
Sarawak General Hospital (SGH).
Methods: Data on demographics and various delays were
collected from the medical records from January 2015 until
March 2018. Patient delay is defined as from the time onset
of symptom to the first primary care presentation. Primary
care delay is defined as from the first primary care
presentation to referral to rheumatology. Rheumatology
delay is defined as from rheumatology referral to
appointment at the rheumatology clinic. Disease modifying
anti-rheumatic drugs (DMARDS) delay is defined as from the
rheumatology clinic appointment to starting DMARDS. Total
delay is from symptom onset to starting DMARDS.
Results: There were 84 new patients diagnosed with
rheumatoid arthritis, out of which 66 were females (78.6%).
The mean age was 54.1±12.0 years. Only 19 patients (22.6%)
were treated with DMARDS within 12 weeks of symptom
onset. The median time for patient delay was four weeks
(Interquartile range (IQR) 2-20 weeks), while the median time
primary care delay was 11 weeks (IQR 4-24 weeks). The
median time for rheumatology delay was zero weeks (IQR 0-
1 week) and the DMARDS delay was zero week (IQR 0). The
median time from symptom onset to DMARDS initiation was
23.5 weeks (IQR 13.25-51 weeks).
Conclusion: The delays in the diagnosis of rheumatoid
arthritis were mainly from the patient and primary care.