1.Hodgkin Lymphoma Mimicking a Large Soft Tissue Sarcoma of The Shoulder: The Essential Role of Immunohistochemistry in Histopathological Diagnosis
Ibrahim Zainal Abidin ; Ahmad Narihan Zulkarnaen ; Awang Ojep Dk Norlida ; Chan Wai Hoong ; Law Huong Ling
Malaysian Journal of Medical Sciences 2012;19(4):73-77
The shoulder and axillary regions contain various complex anatomical structures in close proximity, many of which can give rise to neoplasms. Determining the origin and hence the exact diagnosis of advanced (diffuse) tumours in this region may become problematic. In view of the tumour morphology and the affected location in this case, we highlight the importance of Hodgkin lymphoma immunohistochemistry interpretation in a tumour which was initially suspected to be a soft tissue sarcoma.
2.Cervical Schwannoma: Report of Four Cases
Rohaizam Jaafar ; Tang Ing Ping ; Doris Evelyn Jong Yah Hui ; Tan Tee Yong ; Mohammad Zulkarnaen Ahmad Narihan
The Medical Journal of Malaysia 2012;67(3):345-348
Extracranial schwannomas in the head and neck region are
rare neoplasms. The tumours often present as asymptomatic,
slowly enlarging lateral neck masses and determination of
the nerve origin is not often made until the time of surgery.
Preoperative diagnosis maybe aided by imaging studies such
as magnetic resonance imaging or computed tomography,
while open biopsy is no longer recommended. The accepted
treatment for these tumors is surgical resection with
preservation of the neural pathway. We report four cases of
cervical schwannomas that we encountered at our center
during four years of period. The clinical features, diagnosis and origin, management and pathological findings of these benign tumors are discussed.
3.Diagnostic dilemma of kimura disease of eyelids
Ting Siew Leng ; Mohammad Zulkarnaen Ahmad Narihan ; Than Than Aye
The Medical Journal of Malaysia 2020;75(1):83-85
Kimura disease (KD) is a rare benign chronic inflammatory
disease that presents as a nodule mostly involving deep
subcutaneous tissue of the head and neck region with
frequent regional lymphadenopathy and peripheral blood
eosinophilia. KD shares some clinical and histopathological
similarity with angiolymphoid hyperplasia with eosinophilia
(ALHE). Consequently, KD and ALHE were once considered
variants of the same disease spectrum. We present here rare
cases of Kimura disease and ALHE involving the eyelid and
lacrimal gland and discuss their differential features.