1.POEMS syndrome: A rare paraneoplastic presentation of spinal plasmacytoma
Jer Ming Low ; Sulaila binti Basiam ; Ahlam Naila binti Kori
The Medical Journal of Malaysia 2019;74(4):335-337
The acronym POEMS syndrome was coined for a unique
multisystem disorder characterised by peripheral
neuropathy, organomegaly, endocrinopathies, monoclonal
gammopathy and skin changes. We report a male patient
presenting to us with spinal plasmacytoma complicated with
paraplegia. He was subsequently diagnosed to have POEMS
syndrome and successfully treated with thalidomide and
dexamethasone. Post treatment, he is able to ambulate
independently
2.Brucellosis-induced autoimmune haemolytic anaemia (AIHA)
Woh Wei Mak ; Adrian Mark Masnammany ; Ahlam Naila Kori
The Medical Journal of Malaysia 2019;74(5):443-444
Brucellosis is a rare zoonotic infection caused by small,
fastidious Gram-negative coccobacilli of the genus Brucella
that may be associated with haemolytic complications
including thrombotic microangiopathy and haemolytic
anaemia. We describe a patient with culture confirmed
brucellosis who presented with malaise, high grade fever,
hepatosplenomegaly and Coombs-positive autoimmune
haemolytic anaemia. The patient was successfully treated
with combination of doxycycline and rifampicin with no
further episodes of relapses or haemolysis. Although rare,
the possibility of brucellosis should always be kept in mind
in patients with risk factors who present with haemolysis
and endemic area.