The application of nanoparticles (NPs) has attracted considerable attention as targeted delivery systems. CaCO3 has become the focus due to its advantages including affordability, low toxicity, biocompatibility, cytocompatibility, pH sensitivity and sedate biodegradability and environment friendly materials. In this article, we will discuss the potential roles of CaCO3-NPs in three major therapeutic applications; as antimicrobial, for drug delivery, and as gene delivery nanocarrier.
Antimicrobial agent

Background: In a chemical war during 1961-1971, about 94,000 tons of the herbicides were sprayed over Southern Viet Nam.A main component of the herbicides is dioxin that is very harmful to humans. There are many studies focusing on people\u2019s health due to exposure to dioxin residuals. Objective: To investigate the health issues related to exposure to dioxin residuals. Subjects and method: A retrospective comprehensive survey performed on 4018 people in Cam Chinh commune, Cam Lo district, Quang Tri province and compared with 3987 people in Cam Phuc commune, Cam Xuyen district, Ha Tinh province (controls) based on epidemiological interviews. Results: The morbidity was higher at 6.4% in the herbicides-applied area than in the herbicides-non applied area. In herbicides-applied area, there was a high risk of diseases such as bone connective, genitourinary, blood endocrine system, skin and infectious diseases. Factors such as age, sex, familiar income, drinking, smoking and agricultural chemical usage contributed towards the health of the affected population.Conclusions: Agent orange/dioxin pollutions still have the potential to be hazardous to human health in the herbicides-applied areas.
Dioxin ; agent orange ; disease

The supply center of the Atsumi Hospital handles medicines, medical supplies, slips, stationery, daily necessities, resterilized things, laundries, linen and washing beds among many others. The center is striving to raise the efficiency of the flow of materials within the hospital and undertakes logistics management single-handed. In January 2003, one copier and one lithographic unit out of the total four duplicating and printing machines in the hospital were removed to the suppy center. Since then, the center has been responsible for handling these machines for individual users. How effective this office meanagement system was in saving time, cutting down on costs and increasing the degree of satisfaction felt by employees was examined as part of TQM activities.Between June 2003, when the advance booking system was adopted for the use of the two machines, and January 2004, it was found that the monthly reservation ratio averaged out 38.3%. A questionnaire survey also found that many menbers of the staff were satisfied as they could make good use of time. As regards cost reduction, the monthly rental for the copying machine was curtailed to ¥57,000. This was made possible as members of the supply center made proper use of the copier and lithography.
Copying Processes ; Economic supply ; Agent ; Central ; Hospitals

An investigation of knowledge, attitude and practice of community and vector colony in 200 households in Huong tra District, Hue City and monitoring of survival ability of mesocyclops after releasing them in to water tanks. Results showed that the participation of community and use of mesocyclops in the field training reduced significantly the mosquito colony and number of patients with haemorrhagic dengue fever. The participation also increased the concepts and knowledge of people in the haemorrhagic dengue fever prevention and control the collaborators and pupils played an important role in the interim of mobilizing the contribution of community.
Community based prevention and control of haemorrhagic dengue fever vector and use of biological agent-mesocyclops