1.Credibility of a Newly Developed Sham Needle.
Jongbae Park ; Adrian White ; Hyejung Lee ; Hitoshi Yamashita ; Edzard Ernst
Journal of the Japan Society of Acupuncture and Moxibustion 2000;50(1):111-114
Objective : To develop a sham needle, which is applicable to clinical trials on acupuncture and test its credibility.
Methods : The Park Sham Needle' unit was developed. The apparatus consists of a blunt needle, the shaft of which telescopes into the handle when tapped, so that while the needle appears to have been inserted, it does not actually pierce the skin, and a Park Tube' that is composed of a standard guide tube and an oversize guide tube with a plastic flange at one end which adheres to the skin with double-sided sticky tape. The needle is held in place by the Park Tube. In a credibility test, 56 subjects received our new sham needle on the left LI-4 acupoint and were asked whether or not they felt the needle being inserted into the skin.
Results : Forty-six subjects (82%) were convinced that they received real needle insertion.
Conclusion : Park Sham Needle seems to be applicable to randomised, subject-blinded, and controlled trials on acupuncture.
3.A Pilot Investigation of the Operationalized Predicaments of Suicide (OPS) Framework
Saxby Pridmore ; Pim Kuipers ; Abdul Majeed Zainab ; Sam Restifo ; Adrian Lee ; Julie Appleton
Malaysian Journal of Medical Sciences 2012;19(3):50-56
Background: Suicide may be conceptualized as an escape from intolerable predicaments, in particular, mental illness and environmental stressors. The operationalized predicaments of suicide (OPS) is a 4 category framework designed to assist in the classification of suicide. The objective was to examine whether this framework is potentially useful.
Method: 18 psychiatrists from 6 different countries examined 12 written coroners’ reports of suicide and rated each report according to the OPS. 16 of these raters then also completed a qualitative questionnaire regarding the framework.
Results: In 89.8% of cases the raters where able to make a decision regarding the drivers which led to the suicides. The respondents displayed modest inter-rater correlation (Kappa = 0.42; P < 0.0001). In the qualitative section, respondents supported the face validity of OPS and considered it potentially useful. Feedback allowed improved wording of the OPS instructions.
Conclusion: The OPS has potential as a useful framework. The OPS instructions have been improved and further studies are justified.
5.Hearing Loss amongst the Elderly in a Southeast Asian Population - A Community-based Study.
Jek Chong LEE ; Adrian Noel DANKER ; Yu Han WONG ; Ming Yann LIM
Annals of the Academy of Medicine, Singapore 2017;46(4):145-154
INTRODUCTIONThe aim of this study was to determine the prevalence of hearing loss amongst the elderly population attending community services in Singapore. The usefulness of the Hearing Handicap Inventory for the Elderly Screening version (HHIE-S) in detecting hearing loss was also investigated.
MATERIALS AND METHODSPure-tone audiometry was carried out on a randomly recruited cohort of people (n = 338) over 60 years old and who were attending rehabilitation and social day care services for senior citizens at St Luke's Elder Care centres located throughout the city. Prior to the hearing test, subjects were administered the HHIE-S questionnaire, which was translated into the language they were most conversant in.
RESULTSThe study cohort showed mean pure-tone average at speech frequencies (0.5, 1, 2 and 4 kHz; 4-frequency average hearing level [4FA HL]) of the subjects' better hearing ear that has worsened with age. The percentage of the elderly with disabling hearing impairment (4FA >40 dB HL) was 9.1% (60 to 69 years old), 22.0% (70 to 79 years old), 35.7% (80 years old and above). Across all age groups, males had significantly poorer thresholds at 4 kHz than females. When adjusted for the demographic profile of the country, the prevalence of hearing loss (4FA >25 dB HL) and disabling hearing impairment (4FA >40 dB HL) amongst the elderly in Singapore was 63.7% and 16.2%, respectively. We estimate that there are currently 422,000 elderly with hearing loss greater than 25dB HL and over 100,000 elderly with disabling hearing loss of over 40 dB HL. Of subjects with a disabling hearing impairment, only 7.5% used hearing aids. The use of self-reporting HHIE-S showed poor sensitivity in detecting hearing loss of various severities amongst the elderly.
CONCLUSIONThese data provide estimates of the prevalence and severity of hearing loss in older persons in Singapore and suggest that more can be done to help the elderly recognise, acknowledge and address hearing loss in the country.
6.Risk factors of surgical site infections in hip hemiarthroplasty: a single-institution experience over nine years.
Adrian Cheng Kiang LAU ; Ghim Hoe NEO ; Haw Chou LEE
Singapore medical journal 2014;55(10):535-538
INTRODUCTIONThis study aims to describe the factors associated with surgical site infection (SSI) in elderly patients who underwent hip hemiarthroplasty following a hip fracture, in a single institution over a nine-year period.
METHODSAll patients who underwent hip hemiarthroplasty between 1 January 2004 and 31 December 2012 in our hospital were included in the present study. The detection of SSI was carried out by a trained, independent infection control nurse using the United States Centers for Disease Control and Prevention criteria. Demographic and clinical data were collected retrospectively. Demographics and clinical factors were analysed for potential associations with SSI.
RESULTSAmong the 1,320 patients who met the study inclusion criteria, a total 57 SSIs were documented, giving an infection rate of 4.3%. Patients who waited for more than one week for surgery had a statistically significantly higher risk of SSI (odds ratio 3.030, 95% confidence interval 1.075-8.545, p = 0.036). The presence of SSI was also significantly associated with increased length of hospital stay (p < 0.001). The two main microorganisms detected were methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa, which accounted for 50.9% and 26.3% of the SSIs, respectively.
CONCLUSIONWe concluded that the number of days from admission to surgery is a main risk factor for the development of SSI. Steps should, therefore, be taken to prevent unnecessary delay of surgery in elderly patients requiring hip hemiarthroplasty.
Aged ; Aged, 80 and over ; Female ; Hemiarthroplasty ; adverse effects ; Hip Joint ; surgery ; Humans ; Male ; Retrospective Studies ; Risk Factors ; Surgical Wound Infection ; epidemiology
7.Treatment of coronary in-stent restenosis with drug-eluting balloon catheter: real-world outcome and literature review.
Hong Yuan XIA ; Adrian F H LOW ; Chi Hang LEE ; Swee Guan TEO ; Mark CHAN ; Koo Hui CHAN ; Huay Cheem TAN
Annals of the Academy of Medicine, Singapore 2013;42(1):49-51
Aged
;
Cardiac Catheters
;
Combined Modality Therapy
;
Coronary Restenosis
;
therapy
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Middle Aged
;
Paclitaxel
;
administration & dosage
;
therapeutic use
;
Percutaneous Coronary Intervention
;
instrumentation
;
Stents
;
Treatment Outcome
;
Tubulin Modulators
;
administration & dosage
;
therapeutic use
9.Ultrasound findings in peliosis hepatis
Yi DONG ; Wen-Ping WANG ; Adrian LIM ; Won Jae LEE ; Dirk-Andre CLEVERT ; Michael HÖPFNER ; Andrea TANNAPFEL ; Christoph Frank DIETRICH
Ultrasonography 2021;40(4):546-554
Purpose:
The aim of this study was to retrospectively evaluate contrast-enhanced ultrasound (CEUS) findings in patients with peliosis hepatis (PH).
Methods:
A retrospective analysis was conducted of CEUS features in 24 patients with histopathologically confirmed PH (11 men and 13 women; mean age, 32.4±7.1 years; range, 28 to 41 years). All lesions were histologically proven, either by core needle biopsy (n=10) or by hepatic surgery (n=14).
Results:
The mean size was 36.8±12.4 mm (range, 10 to 80 mm). On B-mode ultrasonography (BMUS), all PH lesions were heterogeneously hypoechoic, with well-defined margins but irregular shapes. No mass effect was observed. During the arterial phase of CEUS, all lesions displayed mild heterogeneous hyperenhancement (83.3%, 20/24) or isoenhancement (16.7%, 4/24). Furthermore, 87.5% of the PH lesions showed mild washout after 1 minute in the portal venous phase (30-120 seconds) and mild washout in the late phase (>120 seconds).
Conclusion
The lack of a mass effect on BMUS, mild heterogeneous arterial hyperenhancement, and washout in the very late portal venous phase (after 1 minute) on CEUS are characteristic of PH. Although it is a histological diagnosis, PH should be considered in the differential diagnosis when the clinical context does not favor a malignancy or infection.
10.Barriers to effective research supervision in clinical specialist training: Experience from a medical school in Malaysia
Lee Yew Kong ; Ng Chirk Jenn ; Sim Joong Hiong ; Firdaus Amira ; Foong Chan Choong ; Hong Wei Han ; Junedah Sanusi ; Adrian Lim Jia Hwa ; Christopher Boey Chiong Meng
Malaysian Family Physician 2021;16(3):77-86
Introduction: A compulsory research component is becoming increasingly common for clinical residents. However, integrating research into a busy clinical training schedule can be challenging. This study aimed to explore barriers to research supervision in specialist training programmes from the perspectives of clinical supervisors and trainees at a Malaysian university hospital.
Methods: Qualitative interviews and focus group discussions were conducted (December 2016 to July 2017) with clinical supervisors (n=11) and clinical trainees (n=26) utilising a topic guide exploring institutional guidelines, research culture and supervisor-student roles. Interviews were transcribed verbatim and analysed thematically to identify barriers to research supervision.
Results: Supervisors and trainees from 11 out of 18 departments participated. Both clinical supervisors and trainees struggled to successfully integrate a compulsory research component into residency training. Among the reasons identified included a lack of supervisory access due to the nature of clinical rotations and placements, clashing training priorities (clinical vs research) that discouraged trainees and supervisors from engaging in research, poor research expertise and experience among clinical supervisors hampering high-quality supervision, and a frustrating lack of clear standards between the various parties involved in research guidance and examination.
Conclusion: Both clinical supervisors and trainees struggled to successfully integrate a compulsory research component into residency training. This was not only an issue of resource limitation since questions regarding clinical priorities and unclear research standards emerged. Thus, institutional coordinators need to set clear standards and provide adequate training to make research meaningful and achievable for busy clinical supervisors and trainees.