1.Dosage of ketoprofen in pharmaceutical products by local capillar electrophoresis
Pharmaceutical Journal 2003;331(11):21-23
Capillary Zone Electrophoresis (CZE) was used to quantify ketoprofen in 50mg ketoprofen capsules and ketoprofen gel 2.5%. The results were compared to results of spectrophotometric UV-VIS method. Results: the accuracies of 2 methods were different but not significant. Results of CZE method were rather lower than spectrophotometric UV-VIS method because impurities were separated in electrophoresis process. The authors concluded that CZE could be used to quantify ketoprofen in products
Ketoprofen
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Electrophoresis
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Adjuvants, Pharmaceutic
2.Dissolution test for some chloramphenicol capsule sample
Journal of Medical and Pharmaceutical Information 2003;10():10-33
This study was aimed to assess the dissolution of 4 chloramphenicol capsule products of 4 Vietnamese pharmaceutical enterprises. The results showed that most of them have a very low drug release degree. The cause may be resulted from making capsule without making particles, too raw powder, using too much insoluble excipient, too high rate of insoluble excipient. The dissolution test should be considered an item of chloramphenicol capsule specification
Chloramphenicol
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Adjuvants, Pharmaceutic
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Capsules
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drugs
3.Some opinions about the subject of importation together with the pharmaceutical domain
Pharmaceutical Journal 2003;234(4):4-6
Importation together is one of essential measures in trying to stable drug ‘s price in the market, protect patients while also ensure requests about understanding property and freedom trade. Discuss about difficulties of Viet Nam in now importation together problem. Along with allow importation together, functional offices, which belong Health need combine well with different industry as market management, customs… to strengthen prevent manufacture unreal products, bad quality products and illegal imported products.
Adjuvants, Pharmaceutic
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Commerce
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Public Opinion
4.Around the problem of the right of intellectual propriety in the pharmaceutical domain
Pharmaceutical Journal 2003;323(3):6-8
Deal with effect of understanding proprietary to development of now pharmaceutical industry, opinions to delay protection of understanding proprietary in pharmaceutical industry in Vietnam and the other countries. Some of measures must be synchronous performed to deploy performing copyright on pharmaceutical industry.
Adjuvants, Pharmaceutic
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Problem Solving
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Drug Industry
5.The task of materia medica in "The development strategy of the pharmaceutical branch during the period till 2010"
Pharmaceutical Journal 2003;234(4):6-8
A number of opinion discuss about relate to medicinal plant and medicine programs which were mentioned in “the development strategy of the pharmaceutical branch during the period till 2010”. The works need do to perform decision of prime minister of government: step by step satisfy material source of making drug and produce making drug material of position of strength, specially from medicine as: additional investigate medicinal plant resources in Viet Nam, practice plant in situation of economic and society development in Viet Nam.
Materia Medica
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Adjuvants, Pharmaceutic
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growth & development
6.Dosage of nimesulide in tablets by second derivative UV spectrum method
Pharmaceutical Journal 2003;234(4):16-18
Used second order derivative UV (200-500nm) spectrum to determine the quantity of nimesulid in tablets without through process of deal with sample. Assess linear interval, limit of detection, limit of determine the quantity between level of nimesulid solution and value of second order derivative in interval of study level, degree of accuracy of the method and result of determine the quantity of nimesulid. The result showed that: process of quantitative nimesulid was built. The method was accurate, sensitive, precise, and reproducible and could be applied directly and easily to the pharmaceutical preparations.
Spectrum Analysis
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Pharmaceutical Preparations
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Adjuvants, Pharmaceutic
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tablets
7.Some opinions on the quality reinforcement of pharmaceutical products with relation to the target of exportation
Pharmaceutical Journal 2003;9():6-11
Pharmaceutical quality, management are important targets to integrate in international pharmaceutical market, raising field's prestige. The authors showed that must review and control several factors in imported and exported records of the products, such as GMP condition of supplier, TSE. Learning about inspected experiences of famous special organizations. Preparing to enhance Vietnam's GMP. To advance pharmaceutical exported program to foreign country
Adjuvants, Pharmaceutic
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Reinforcement (Psychology)
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Pharmaceutical Preparations
8.Quantifying evaluation of some pharmaceutical products in the form of tablets and capsules by domestic production according to standards of Vietnamese Pharmacopoeia III
Pharmaceutical Journal 2003;326(6):24-26
Experimental studies were carried out concerning the disintegration of 10 preparation of tablet, capsules with various group of medicinal products, produced and distributed by the Pharmaceutical Enterprise X including tablets of paracetamol, tablet of indomethacine, tablet of isoniazid, tablet of metronidazol, tablet of quinin sulfate, tablet of papaverin hydrochloride, tablet of theophylin and tablet of chloroquin phosphate. Results showed that 9 preparations (90%) satisfied the criterions of disintegration
Pharmaceutical Preparations
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Adjuvants, Pharmaceutic
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Capsules
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drugs
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tablets
9.Some opinions on the development direction of the Vietnam Pharmaceutical branch in the period 2002-2010
Pharmaceutical Journal 2003;321(1):3-6
The strategy of pharmaceutical industry for 2002 - 2010 period” that was approved by Primer Minister mentioned to the need of build-up priority policies for businesses which have invested to researching, developing and innovating the pharmaceutical technology, encouraging the use of generic drug and medications made in Vietnam. An authority for nationwide regulating the medication price should be established as soon as possible. The Drug Management Administration should play more active role as a bridge between manufacturers, prescribers and patients. The national manufacturers should consider employing international experts to approach and learn their experiences and management models as well as acquaint with regulations in GMP. Out-state drug quality surveillance should be available
Adjuvants, Pharmaceutic
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Drug Industry
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Technology, Pharmaceutical
10.Preliminary study on manufacture process of transdermal patch of nitroglycerin
Pharmaceutical Journal 2003;321(1):15-18
Nitroglycerin, a vasoactive substance, has been used in the treatment of vagina for more than 100 years. To sustain the pharmaceutical effect, doses were administered every 2 hours. Recently the transdermal delivery systems have became popular. Based on eudragit E 100, we combined it with plasticizer (dibutyl sebacate/triethyl citrate), crosslinker (succinic acid), active ingredient (nitroglycerin) and further excipients (e.g. permation enhances: ethyl alcohol) to form a self adhesive matrix system for use in nitroglycerin patch. The concentration of nitroglycerin in the patch was determined by HPLC assay
Nitroglycerin
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Chromatography, High Pressure Liquid
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Adjuvants, Pharmaceutic