Objective To compare the efficacy and safety of Foley catheter (FC) and prostaglandins (PG) for cervical ripening used in labor induction of late pregnant women with unfavorable cervix. Methods Several databases including Cochrane Library,Embase,PubMed,Elsevier,Wanfang Medical Database, CNKI, VIP were searched for collecting the related literatures according to criteria for inclusion and exclusion.Meta analysis was performed by applying software Review Manager 5.2. Results Thirty randomized controlled trials were included.The FC group presented significantly lower risk of excessive uterine contraction [OR= 0.38,95%CI(0.19,0.75),P<0.05] than the PG group.There was no significant difference between the two groups in terms of Cesarean section rate, vaginal delivery rate, Bishop score improvement, duration of induction to delivery, neonatal birth weight, or in neonatal outcome. Conclusion This study shows that FC has good promoting effect of cervical maturity and maternal￣ neonatal outcomes, and rarely produces excessive uterine contraction.It is safe and equally effective as PG does.The approach is easy to operate and worth to apply in clinical use.

Objective: To investigate the prevalence and influencing factors of hyperuricemia among adults in Xinjiang Uygur Autonomous Region, so as to provide insights into the prevention and intervention of hyperuricemia. Methods: Permanent residents at ages of 18 years and above in 8 counties (cities, districts) of Xinjiang Uygur Autonomous Region were sampled using a multi-stage cluster random sampling method from July 2018 to November. Demographic data, smoking, alcohol consumption, body mass index and serum uric acid were collected through questionnaire surveys, physical examination and laboratory testing. Factors affecting hyperuricemia were analyzed using a multivariable logistic regression model. Results: A total of 4 690 residents were collected, including 2 093 males (44.63%) and 2 597 females (55.37%), and had a mean age of (49.45±14.57) years. There were 1 795 overweight residents (38.27%), 1 198 residents with obesity (25.54%), 983 smokers (20.96%), 1 224 drinkers (26.10%), and 268 residents with hyperuricemia (5.71%). Multivariable logistic regression analysis showed that a higher risk of hyperuricemia was seen among adults who were males (OR=1.409, 95%CI: 1.036-1.917), aged 60 years and above (OR=2.092, 95%CI: 1.495-2.928), had high school education or above (high school, OR=2.003, 95%CI: 1.366-2.937; college and above, OR=4.876, 95%CI: 3.196-7.438), were overweight (OR=2.343, 95%CI: 1.618-3.395) or obese (OR=4.754, 95%CI: 3.291-6.868) and had alcohol consumption (OR=1.494, 95%CI: 1.104-2.020). Conclusion The risk of hyperuricemia may be associated to gender, age, educational level, body mass index and alcohol consumption among adults in Xinjiang Uygur Autonomous Region.