1.Intradural Extramedullary Non-infiltrated Solitary Metastatic Tumor.
Young Jin JUNG ; Sang Woo KIM ; Chul Hoon CHANG ; Soo Ho CHO
Journal of Korean Neurosurgical Society 2005;37(6):466-468
Spinal intradural extramedullary non-infiltrated solitary metastasis is very rare. We report a case of intradural extramedullary carcinoma to the T9 nerve root, which mimiking a nerve sheath tumor. Pathology reveals metastatic adenocarcinoma. We discuss the feature of mechanism and pathogenesis and management strategy follows.
Adenocarcinoma
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Neoplasm Metastasis
;
Pathology
2.CT findings of bronchioloalveolar carcinoma: correlation with pathology.
Eun Ju YU ; Jung Gi IM ; Chun Whan HAN ; Hye Kyung YOON ; In Ok AHN ; Kyung Hwan LEE ; Goo LEE ; Man Chung HAN ; In Ae PARK ; Eu Keun HAM
Journal of the Korean Radiological Society 1992;28(1):73-77
No abstract available in English.
Adenocarcinoma, Bronchiolo-Alveolar*
;
Pathology*
3.Consideration of diagnosing extremely well differentiated adenocarcinoma of gastrointestinal tract.
Chinese Journal of Pathology 2022;51(8):693-695
For gastrointestinal adenocarcinoma with excellent differentiation, some diagnostic names have emerged in recent years, which have overlapping and different meanings. Low-grade well differentiated adenocarcinoma and very well differentiated adenocarcinoma are terms for a group of adenocarcinomas with good differentiation and little cellular atypia, including a variety of histological types. It is suggested that specific histological types should be listed as far as possible in diagnosis, instead of using "low-grade well differentiated adenocarcinoma" or "very well differentiated adenocarcinoma" as a complete diagnosis. This kind of adenocarcinomas may lack cellular pleomorphism, so it is necessary to observe the structural atypia for diagnosis. At the same time, attention should be paid to the differentiation of reactive changes, low grade dysplasia, epithelial misplacement and other lesions.
Adenocarcinoma/pathology*
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Gastrointestinal Tract/pathology*
;
Humans
8.Advances in pathological study of micropapillary lung adenocarcinoma.
Chinese Journal of Pathology 2023;52(11):1183-1188
10.Histomorphology of aberrant crypt foci in colorectal carcinoma.
Norlida, A Ojep ; Phang, Koon Seng
The Malaysian Journal of Pathology 2010;32(2):111-6
Colorectal carcinogenesis is a complex multistep process that includes changes in histomorphological appearance of the colonic mucosa and changes at molecular level. Aberrant crypt foci (ACF) was first described by Bird in 1987 on examination of methylene-blue-stained colonic mucosa of azoxymethane-treated mice under light microscopy. Since then ACF was considered as the earliest preneoplastic change that can be seen in the colonic mucosa. The aim of this study was to look at the histomorphology and distribution of ACF in colorectal carcinoma. 50 formalin-fixed archival colectomy specimens for colorectal carcinoma were examined under light microscopy after staining with 0.2% methylene blue. ACF was identified by larger and darker crypts with thickened epithelium, and often elevated from adjacent normal mucosa. ACF was found in 41 of 50 colectomy specimens examined. There were 328 ACF consisting of 36 (11.0%) ACF without hyperplasia or dysplasia, 263 (80.2%) ACF with hyperplasia and 29 (8.8%) ACF with dysplasia. Of these 29 ACF with dysplasia, 25 showed low grade dysplasia and four high grade dysplasia. The density of ACF was higher in the left colon, those older than 65 years of age and among males but these findings were statistically not significant. The crypt multiplicity of hyperplastic ACF (30.149, SD 28.395) was larger than dysplastic ACF (20.613, SD 40.128). The spectrum of histological changes observed probably represent the evolution of ACF in colorectal carcinogenesis.
Aberrant Crypt Foci/*pathology
;
Adenocarcinoma/*pathology
;
Colorectal Neoplasms/*pathology