1.Usefulness of NS5 Antibody Measurement in Recombinant Immunoblot Assay (RIBA) as a Clinical Test for Confirmation of Asymptomatic HCV Infection
Yukihito MINATO ; Naoko MOCHIZUKI ; Keiji KOSHIBU ; Kouji HATTORI ; Tatsuo SHIIGAI
Journal of the Japanese Association of Rural Medicine 2005;54(4):640-643
Using RIBA NS5 antibody was measured in 31 HCV RNA positive serotype 1 patients, and the serum levels of ALT were monitored for an average of three years. As a result, 22 asymptomatic HCV carriers (group A) were found to be NS5 antibody negative (-) and nine to be NS5 antibody positive (4+). By contrast, in 25 patients with chronic inactive hepatitis C (group B), three patients were NS5 antibody negative (-), and 22 patients were NS5 antibody positive (4+), indicating a significant difference between the two groups (p<0.01 chi square test).Furthermore, in group A, 22 NS5 antibody (-) patients (group I) maintained normal serum levels of ALT significantly longer than the 9 NS5 antibody (4+) patients (group II) (p<0.01, Kaplan-Meier Method). Therefore, the measurement of NS5 antibody of RIBA was clinically useful in identifing asymptomatic (HCVRNA positive, serotype 1) HCV carriers.
Antibodies
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Hepatitis C virus
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Absence of symptoms
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Measurement
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Confirmation of
2.Ancient Schwannoma of the cervical sympathetic chain: A case report.
Primuharsa Putra Sabir Husin Athar ; Norleza Ahmad Norhan * ; Megat Shiraz Megat Abdul Rahman
Malaysian Journal of Medical Sciences 2007;14(1):75-78
Schwannoma of the cervical sympathetic chain is an extremely rare nerve tumour. We report an unusual swelling in a 41-year-old female who presented with an asymptomatic solitary mass in the right parapharyngeal space. Clinical examination and computed tomography showed displaced carotid artery in an antero-medial direction. Surgical excision of the lesion was carried out and histological examination revealed an Ancient Schwannoma.
Neurilemmoma
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Case Report
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Absence of symptoms
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Lesion, NOS
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X-Ray Computed Tomography