Objective To detect the changes of serum lipid levels in diabetic peripheral neuropathy patients,investigate the relationship between ApoB and HOMA-IRI and diabetic peripheral neuropathy.Methods One hundred and eighty-two patients with type 2 diabetes mellitus admitted to the medical department of Xuanwu Hospital Capital Medical University from January 2015 to August 2016 were enrolled in this study.All patients underwent EMG detection,the MCV of bilateral median nerve,tibial nerve and common peroneal nerve,and the SCV of median nerve,ulnar nerve and sural nerve.According to the detection results and symptoms and signs,the subjects were divided into type 2 diabetic peripheral neuropathy group (DPN,86 cases) and type 2 diabetic non peripheral neuropathy group (NDPN,96 cases).The general demographic data of the two groups was recorded,including TC,TG,HDL-C,LDL-C,FBG,HaBlc,FINS,UA,UAE and HOMA-IRI,to analyze the relationship between the nerve conduction velocity in type 2 diabetes patients with peripheral neuropathy and HDL-C,LDL-C,FINS,HbAlc,ApoB,HOMA-IRI.Results The course of disease in patients with type 2 diabetic peripheral neuropathy ((9.53 + 2.38) years,UAE (22.24) mg/L) was higher than that in patients with type 2 diabetic non peripheral neuropathy ((6.37 + 1.59) years and UAE (9.83) mg/L);FINS and HOMA-IRI levels in the DPN group were lower than those in the NDPN group ((16.33±2.33) vs.(35.16±5.02),4.94 vs.15.27,t=10.629,4.459,31.842,3.128,P<0.05);the level of TG,LDL-C and ApoB in patients with type 2 diabetic peripheral neuropathy was higher than those in patients with type 2diabetic non peripheral neuropathy,and the difference was statistically significant (P<0.05);the disorder of lipid metabolism in the DPN group was serious,whose occurrence rate was higher compared with the NDPN group (P<0.05);the MCV of median nerve was negatively correlated with ApoB (r=-0.278,P=0.041),SCV was positively correlated with HDL-C (r=0.425,P=0.002);MCV of tibial nerve was positively correlated with HDL-C (r=0.335,P=0.031),SCV of ulnar nerve was positively correlated with HDL-C (r=0.425,P=0.004) and FINS (r=0.387,P=0.006),negatively correlated with HOMA-IRI (r=-0.405,P=0.008);sural nerve SCV was positively correlated with HDLD-C (r=0.532,P=0.001),and HbAlc (r=-0.383,P=0.005),negatively correlated with LDL-C (r=-0.361,P=0.018).Conclusion Nerve conduction velocities in patients with type 2 diabetic peripheral neuropathy were associated with HDL-C,LDL-C,FINS,HbAlc,ApoB,and HOMA-IRI.

Hyperoxia, including hyperbaric oxygen (HBO) and high-concentration oxygen (HO), has an important therapeutic effect on various ophthalmological diseases, such as retinal vein occlusion, ischemic optic neuropathy and central serous chorioretinopathy. However, excessive inhalation of oxygen of high-concentration or high atmospheric pressure can cause damage of ocular tissue, in which the lens opacity and retinopathy of prematurity (ROP) are the most common complications following hyperoxia exposure. At present, the pathogenesis of hyperoxia-induced ocular injury is still unclear thoroughly, and it may be related to oxidative stress, lipid peroxidation and inflammation. This article reviewed the current advance in the mechanism and the potential prevention of hyperoxia-induced the lens,retina and other ocular injuries.

Objective To explore the optimum dose of multislice spiral CT scan in the check of patients with chronic obstructive pulmonary disease(COPD).Methods 90 COPD patients were divided into the conventional dose group and low dose group,the quality of conventional-dose and low-dose scan was analyzed respectively.Results The two scanning methods enable images satisfactory requirements in the 90 cases,and low-dose CT radiation dose was significantly reduced(t=5.01,6.82,both P＜0.05).Conclusion For COPD patients using multi-slice spiral CT scan,low-dose scanning can not only meet the requirements of clinical diagnosis,but also significantly reduce the patient radiation dose.

Objective To investigation and analysis the related factors of delayed treatmen (pre-hospital and in-hospital) in pa-tients with acute myocardial infarction (AMI) .Methods 218 patients with AMI from inpatient department of cardiology and emer-gency ,and to analyze the factors that may affect patients medical timely through investigated and analyzed more than 20 specific fac-tors ,including general information ,human and social factors ,etc .Results In 218 case of AMI ,47 cases of timely treatment (21 .6% ) ,171 cases of delaying treatment (78 .4% ) in 218 patients with AMI .The results showed that education level ,disease awareness level ,economic income ,previous history of heart disease ,chest pain level ,treatment distance ,transport choices and whether call a first-aid or not had significant differences between timely treatment group and delaying treatment group (P<0 .05) . Hospital diagnosis and treatment delay may link with waiting time ,waiting for examination ,the doctor′s advice-delivery time .Con-clusion Patients with AMI treatment delay is serious ,the awareness of patients timely treatment and hospital management system should be further improved .

OBJECTIVE To discuss the risk factors of surgical site infection and to provide the basis for the infection control.METHODS Strengthening the organization management and training emphasizing the measures such as the skin disinfection of the medical care personnel hands and the patients before operation,carrying out the asepsis operation correctly,cleaning the disinfection surgery instrument strictly and enhancely the management of perioperative patients were carried out.RESULTS Of the 74 investigated hospitals,16% were unqualified in preparing or over-preparing skin and the disinfection method;20% were without antibacterial bathes before operation and 64% were inproper time of in skin preparing.CONCLUSIONS Well monitoring of surgical site is the important means to prevent the surgical-site infections,and enhancing management of perioperative patients is the key to control infection.

Objective To design and develop a Network Management Information System (NMIS) for military medical service and training in military academies and combat troops. Methods In order to perform network management and application of Web system in management of training equipment,materials,teaching textbooks,training budget and training assessment,optimum design of the system was achieved using Visual Studio. Net 2005,C# Language and SQL Server 2005 data base,combined with component and AKAX technologies. Results The system turned out to be effective in the detailed management and process control of equipment,materials and budget in military medical service training. Conclusion The system can effectively change the management modules in military medical service training and logistics support and it has achieved the goal of scientific,standardized and computerized management,thus providing an effective system for the modernization of management of the military medical service training.

Objective Ovariectomized rats are the most suitable model for the study of postmenopausal osteoporosis.However,the effect of ovariectomy on rat skin is little studied.The aim of this study was to observe the effect of ovariectomy on the skin aging indexes in rats.Methods 20 healthy 3-month-old female SD rats were randomly divided into sham group and ovariectomized (OVX) group.Serum estradiol was detected at 3 months after ovariectomy,the skin aging-related biochemical indexes such as catalase (CAT),glutathione peroxidase (GSH-Px),superoxide dismutase (SOD) activity and the content of malondialdehyde (MDA),hydroxyproline (HYP) and lipofuscin (LF) were also detected.The structure of skin tissue was observed and detected using a pathological image analysis system.Results The serum E2 of OVX rats was significantly lower than that in the sham group,the thickness of epidermis and dermis of OVX group was significantly thinner than that of the sham group (P<0.01),the amount of collagen fibers was decreased and their arrangement was very loose.Compared with the sham group,the activity of CAT,GSH-Px and SOD in the OVX group was significantly decreased (P<0.01),and the content of MDA was significantly increased (P<0.01).The content of HYP in skin tissue was significantly decreased,and LF content was significantly increased (P< 0.01) in the OVX group.Conclusions Skin aging can be induced at 3 months after ovariectomy in 3-month old rats,which may be a good model for the study of skin aging in postmenopausal women.

OBJECTIVE:To briefly analyze the fresh herb processing and application methods in Shengcao Yaoxing Beiyao, and to offer references for modern fresh herb application. METHODS:All 311 herbs stated in Shengcao Yaoxing Beiyao were stud-ied individually to record their processing and application methods from property and performance. RESULTS & CONCLUSIONS:19 fresh herb processing methods and 25 application methods were recorded in this book. The 19 fresh herb processing methods in-cluded juicing method,mud method,soaking method,water-boiling method,wine-boiling method,ten-steaming and nine-basking method,carbon method,burning-ash method,chewing method,mincing method,cooking method,and so on. The 25 application methods of fresh herbs included applying,scraping,painting,sticking,washing,spreading,immersing,bathing,ear-dropping, fuming,oral administration with wine,mouth-keeping,juice-drinking,boiling,water-boiling-drinking and tea-drinking,frying, decocting,toasting,steaming,blending,stewing,oral administration with tea,pastry,brewing,alleviating fishy smell,and so on. It is necessary to strengthen the origins research and re-research of herbs,and develop several empirical studies about the influ-ence for fresh herbs’effective ingredient quantitative change by their processing methods,and the influence for fresh herbs’phar-macology index by application methods,in order to form intellectual property.