1.Pain in Times of Stress
Asma Hayati Ahmad ; Rahimah Zakaria
Malaysian Journal of Medical Sciences 2015;22(Special Issue):51-60
Stress modulates pain perception, resulting in either stress-induced analgesia or stress-induced hyperalgesia, as reported in both animal and human studies. The responses to stress include neural, endocrine, and behavioural changes, and built-in coping strategies are in place to address stressors. Peculiar to humans are additional factors that modulate pain that are experienced in times of stress, notably psychological factors that potentially influence the directionality of pain perception.
2.CLINICAL OUTCOME OF ILIZAROV EXTERNAL FIXATION (IEF) IN SUPRACONDYLAR FEMUR FRACTURES
Kandiah S ; Toyat SS ; Zulkifli EM ; Kamarul AH
Malaysian Orthopaedic Journal 2019;13(Supplement A):20-
3.Lengthening On A Nail Using LLRS:A Case Series
Malaysian Orthopaedic Journal 2019;13(Supplement A):270-
4.Serum Vascular Endothelial Growth Factor (VEGF) as a Biomarker for Disease Activity in Lupus Nephritis
Wan Syamimee Wan Ghazali ; Rahimah Iberahim ; Noor Suryani Mohd Ashari
Malaysian Journal of Medical Sciences 2017;24(5):62-72
Background: Previous studies have shown that serum VEGF levels were elevated in
patients with active systemic lupus erythematosus (SLE), especially in those with lupus nephritis
(LN). In this case control study, we aimed to compare serum levels of VEGF in SLE patients
between LN, non-LN and healthy participants to determine the association between serum VEGF
levels and the activity and histological classes of lupus nephritis.
Methods: Blood samples were obtained from 92 SLE patients (46 LN and 46 non-LN) and
26 controls. Data were collected from medical records. Serum VEGF assays were performed by
specific, enzyme-linked immunosorbent assay kits (ELISA). Laboratory investigations included
urinalysis, urine protein–creatinine ratio, serum creatinine, albumin and VEGF levels. Blood
pressure, renal biopsy result and treatment were recorded. LN activity was evaluated using
the renal subscale of the British Isles Lupus Assessment Group (rBILAG, 2004). The rBILAG
measures blood pressure (diastolic and systolic), urine protein, serum creatinine, calculated
glomerular filtration rate (GFR), presence of active urinary sediments and histological evidence of
active nephritis.
Results: Serum VEGF was elevated in SLE patients with LN compared with the non-LN
group and healthy controls. The levels found were significantly higher in the sera of patients with
active nephritis compared to those with quiescent nephritis (P = 0.024). The study did not find a
statistically significant relationship between serum VEGF levels and histological classes of LN.
Conclusion: There was no significant difference of serum VEGF level between LN and
non-LN SLE groups and between the non-LN group and healthy controls. However, there were
increased levels of serum VEGF in the LN group, especially in patients with active nephritis as
compared to quiescent nephritis group. This reflects the role of VEGF in the pathogenesis of lupus
nephritis, however the clinical potential of this biomarker needs further study.
5.Infestation of gill copepod Lernanthropus latis (Copepoda: Lernanthropidae) and its effect on cage-cultured Asian sea bass Lates calcarifer
Kua Beng Chu ; Noraziah Mat Rashid and Nik Rahimah Abd. Rani
Tropical Biomedicine 2012;29(3):443-450
Twenty Asian sea bass Lates calcarifer from a floating cage in Bt. Tambun, Penang were examined for the presence of parasitic gill copepod, Lernanthropus latis. The prevalence of L. latis was 100% with the intensity of infection ranging from 1 to 18 parasites per host or
3.75 of mean intensity. Female parasites having oblong cephalothorax and egg-strings were seen mainly on the entire gill of examined Asian sea bass. The infected gill of Asian sea bass was pale and had eccessive mucus production. Under light and scanning electron microscopies
(SEM), L. latis was seen grasping or holding tightly to the gill filament using their antenna, maxilla and maxilliped. These structures are characteristically prehensile and uncinate for the parasite to attach onto the host tissue. The damage was clearly seen under SEM as the hooked end of the antenna was embedded into the gill filament. The parasite also has the mandible which is styliform with eight teeth on the inner margin. The pathological effects such as erosion, haemorrhages, hyperplasia and necrosis along the secondary lamellae of gill filaments were seen and more severe at the attachment site. The combined actions of the antenna, maxilla and maxilliped together with the mandible resulted in extensive damage as L. latis attached and fed on the host tissues.
6.Klebsiella Pneumoniae Liver Abscess With Hematogenous Long Bone Osteomyelitis
Malaysian Orthopaedic Journal 2019;13(Supplement A):138-
7.CLINICAL OUTCOME OF PREOPERATIVE PHYSIOTHERAPY ON POSTOPERATIVE TRIGGER FINGER RELEASE FINGER FUNCTIONAL RECOVERY
Jeffrey S ; Abdullah Aqeel M ; Andrew Mak SK ; Anthony M ; Arief Y ; Saravanan A ; Mohd Ashraf AM ; Nur Atiqah MJ ; Farid M ; Syahril Rizal A ; Kamarul Al-Haqq AG
Malaysian Orthopaedic Journal 2019;13(Supplement A):17-
8.A COMPARISON OF SHORT TERM OUTCOME BETWEEN CANNULATED SCREW FIXATION AND NON-LOCKING RECONSTRUCTION PLATING OF DISPLACED ACETABULAR FRACTURES
Jeffrey S ; Mohd Ashraf AM ; Rostam M ; Rushdie I ; Fikry MI ; Muhaimin M ; Ng MG ; Arief Y ; Syed Z ; Jeffrey C ; KamarulAl-Haqq AG
Malaysian Orthopaedic Journal 2019;13(Supplement A):39-
9.TECHNICAL CHALLENGES AND SHORT TERM OUTCOME OF CANNULATED SCREW FIXATION OF PELVIC RING AND ACETABULAR FRACTURES
Jeffrey S ; Mohd Ashraf AM ; Rostam M ; Fikry MI ; Esanikaruppiah J ; Bryan Teoh CE ; Nur Atiqah MJ ; Abdullah Aqeel M ; Saravanan A ; Mohd Naim N ; Kamarul Al-Haqq AG
Malaysian Orthopaedic Journal 2019;13(Supplement A):46-
10.Prevalence of hypoglycaemia among insulin-treated pregnant women with diabetes- who achieved tight glycaemic control.
Danish NG ; Nurain Mohd NOOR ; Sy Liang YONG
Journal of the ASEAN Federation of Endocrine Societies 2019;34(1):29-35
OBJECTIVE: To determine the prevalence of hypoglycaemia using continuous glucose monitoring system (CGMS) among insulin-treated pregnant women with diabetes whose glycosylated haemoglobin (HbA1c) were <6.0% and identify the risk factors associated with hypoglycaemia occurrence.
METHODOLOGY: We conducted a cross-sectional study using 6-days CGMS to detect the prevalence of hypoglycaemia in 31 insulin-treated pregnant women with diabetes who achieved HbA1c <6.0%. Patients were required to log-keep their self-monitoring blood glucose (SMBG) readings and hypoglycaemia events.
RESULTS: Eight women experienced confirmed hypoglycaemia with additional seven experienced relative hypoglycaemia, giving rise to prevalence rate of 45.2% (one had both confirmed and relative hypoglycaemia). Nine relative hypoglycaemia and 17 confirmed hypoglycaemic events were recorded. Sixteen (94%) out of 17 confirmed hypoglycaemia events recorded by CGMS were asymptomatic and were missed despite performing regular SMBG. Nocturnal hypoglycaemia events were recorded in seven women. Univariable analysis did not identify any association between conventional risk factors and hypoglycaemia events in our cohort.
CONCLUSION: Insulin-treated pregnant women with diabetes who achieved HbA1c < 6.0% were associated with high prevalence of hypoglycaemia. Asymptomatic hypoglycaemia is common in our cohort and frequently missed despite regular SMBG. Present study did not identify any association between conventional risk factors and hypoglycaemia events in our cohort.
Human ; Female ; Hypoglycemia ; Pregnancy ; Diabetes Mellitus