Risk of malarial outbreak and measures of malaria control at A Luoi district, Thua Thien Hue province during 1997-1998. Malaria prevention and control activity at A Luoi district, Thua Thien Hue province during 1991-1996 improved. The morbidity and mortality decreased gradually, the malaria outbreak did not happen for many years and was stable. However, malaria tended to return during 1997-1998, the outbreak happened. The outbreak surveillance had been applied by looking at monthly malaria chart and compared with +2SD chart. Basing on this basis, the investigation and intervention has been made timely and appropriately to control the outbreak effectively
Malaria ; artesunate

The introduction of permethrine - impregnated bednets has effectively contributed to decrease malaria cases in ethnic communities at Thua Thien - Hue province. Malaria attack rate was 15.05 per thousand in 1992, 8.54 per thousand in 1994, and 3.30 per thousand in 1997
Malaria ; artesunate ; epidemiology

125 alternative treatment providers (ATPs) in 3 provinces Son La, Gia Lai and Song Be were investigated using in-deep interviews. Antimalarial drugs were sold in > 95% of these ATPs. Almost all common antimalarials with different formulation and from different sources were available. Pharmaceutical inspection should be strengthened
Malaria ; artesunate ; Pharmaceutical Preparations

Clothers with hats and mosquito nets made from Olyset tried on 50 people who were working out-door at nights and 50 people who were sleeping with mosquito nets indoor at nights. 100 control people divided into 2 groups. Results showed that mosquito density indoor decreased significantly, clinical malaria and malarial parasite reduced from the 2nd month to the 4th month. There was no case of clinical malaria and malaria parasite on the 5th month. There was no major change in the control groups before and after experiment. After 7 to 10 months of experiment, no major changes of falling mosquito (80%) when contacted with Olyset net within three minutes
Malaria ; artesunate ; prevention & control

An evaluation of the malaria control activity in 2000 has shown that the malaria control activity has obtained some achievements including no big outbreak, reduction of morbidity number and mortality number to 50% and 60%, respectively when comparing with these in 1995. This paper presented some shortcoming such as the high morbidity and mortality, malaria in the central highland, limited diagnosis, treatment, education and communication in the local level, especially in remote areas as well as unstable equipment and material
Malaria ; artesunate ; prevention & control

In past ten years, the socialized activity has contributed an important part in improving the malaria situation of VietNam, with remarkable achievements are: after 10 years (1991-2000), the malaria mortality reduced by 96.8%, malaria incidence reduced by 73%. Malaria outbreaks reduced by 98.6% and many locals have created sustainable factors to maintain the result of malaria control
Malaria ; artesunate ; prevention & control

From 1991, the Vietnam has been implementing the National malaria control program aiming at the reduction of outbreak, morbidity and mortality. This program has obtained some primary achievements including interruption of malaria outbreak, reduction of malaria epidemy, and morbidity and mortality
Malaria ; artesunate ; prevention & control

An investigation on 31 communes at Thua Thien - Hue province, with the total of 116 times of investigations had collected 29 species of Anopheles mosquitoes with 2 varitae: Anopheles Meigen, 1818 (10 species) and Cellia Theobald, 1902 (19 species). The predominant species were An. Sinensis, An. Aconitus and An. Philippinensis. 2 major mosquito vectors were An.dirus and An. Minimus, however they accounted for low rates
Malaria ; artesunate ; prevention & control

Achito compound was prepared by the grft-copolymerization of artesunate and chitosan. The dynamic of Achito hydrolytis process into artesunate and chitosan has been studied. The obtained results showed that: the artesunate content has been quickly released from polymeric carrier in the first hour, then it was slowly liberated in the following 24 hours. At the 24th hour 99% artesunate was released from the Achito. After 48 hours 100% artesunate was released.
Artesunate ; Pharmaceutical Preparations

Artesunate has been produced and used in Vietnam since 1993, but up to 1998, we only produced and used artesunate for tabletting. Since 1998 a research program of injectable artesunate was launched by Ministry of Health. We have succeeded in the production of artesunate powder for injection in two steps: -Producing high quality artesunate powder for injection from the high quality artesunate.
Artesunate ; Pharmaceutical Preparations