Nine compounds derivated from 2-mercaptobezothiazole were synthesized. Their structure have been identified by MS-, IR-, and UV- spectroscopy. Antimicrobial activities of some compounds have been tested. Hydrazide BT6 and substituted hydrazides BT7, BT8, BT9 were found to have significant inhibitory activity on P. aeruginosa, S. aureus, Asp. niger and F. oxysporum at concentration 50mcg/ml.
Pharmaceutical Preparations

Realtime xCELLigence analysis (RTCA) is a new cell detection technology to continuously monitor, record and analyze a variety of information generated by cell activity. In drug research, it plays an important role in assessing myocardial toxicity and cell biological activity. Here, we first introduce the underlying mechanisms and characteristics of RTCA. Then we review the applications of RTCA in the research of myocardial toxicity and cell biological activity, to provides the fundamental baseline for understanding and exploiting RTCA. With the real-time, unlabeled, non-invasive, high throughput, and high accuracy features, RTCA not only promotes drug research and development, but also has a broad and good application prospect in other fields.
Pharmaceutical Preparations

According to the results of an investigation on 270 households in May 1999 carried out in Tien Son district, Bac Ninh province, 56 (20.79%) purchasing households came to commune health centre, 195 (72.22%) came to private clinic, 8 (2.96%) came to public pharmacy and 11 (4.03%) came to private pharmacy. Quality of the drug, easiness to access, reasonable price, good counseling... are the favorable factors to promote the purchaser's choice
Pharmaceutical Preparations ; Pharmaceutical Services

The opening, comparing results before and after treatment clinical trial was performed to abserve the effects of Weitai 999 (an oriental medicine imported from China) on 60 patients with chronic gastritis, were treated by 500 mg of Weitai 999, 4 tablets a day for 30 days. The results showed that 81.2% of patients did not have upper abdominal pain. Endoscopy showed 71.7% of patients had not gastric mucosal inflammation after treatment. Histopathology showed good effect on activity of inflammation in 75.4% of patients. The rate of HP eradication was 34.5%. There was not clinical side effects
gastritis ; Therapeutics ; Pharmaceutical Preparations

Basing on the law of people's health protection, the decree of No 23/H§BT, the decree of No 68/CP, the decision No1203/BYT-Q§, Ministry of Health have been made a decision about promulgation of lists of ingredients and pharmaceutical forms not receiving registration file for domestic and foreign pharmaceutical products.
Pharmaceutical Preparations ; Jurisprudence

Figures of buying turnover grow; total expense and transport expense structure; use of capita resource; resource structure and distribution were studied. Results: Company’s activity is stable and gradually developing; the business scale is expanded, resource is richened, the capital is well managed.
Commerce ; Pharmaceutical Preparations

In order to develop internal force and economic practice, continuously regulate a management task, use safely, sensibly, economically drug in the hospitals and contribution on the pharmaceutical Branch of Vietnam. Ministry of Health have been had direction of number of 04/1998/CT-BYT dated April 3th 1998 with 5 contents.
Pharmaceutical Preparations ; Safety ; Economics

The results of study show that the uses of the imported expensive drugs are increasing, the antibiotics are used as encircle, use of the drugs are out of regulated list, the adverse effects of drugs are not considered and there have not been the process for drug management. From having the drug and therapy council: the rate of use of domestic drugs is increased from 17% to 31.8%; the antibiotics are used as guidline, antibiotic sensitivity test and combined diagnose; the amount of antibiotic is reducing gradually during 95-97. The prescription is implemented as regulation of hospital. There has been the procedure of drug supply and dispensing.
Pharmaceutical Preparations ; hospitals

I. Introduction of film-coating technique; II. Materials: films, pigments and solvents; III. Equipment: Modified coater, Fluidized-bed coater; IV. Formulating solution: Formulating, Calculating amount of solution; V. Types of film: Protective film, Bowel dissoluble film, longer releasing film; IV. Film coating technique using water instead of organic solvent; VII. Testing quality of film coat: Testing polymer and formula, Testing protective, bowel dissoluble and longer releasing film.
Pharmaceutical Preparations ; Meta-Analysis

1,000 households (25.75%) were selected randomly from 3,883 households, included 6,125 persons in Co Nhue Commune, Tu Liem district, Ha Noi City from January to March, 1998. It is found that the medications were mainly required for common cold, fever, cough and fatigue. The drug consumers were involved in every age groups, in which the drug consumption was higher in under-5-year children due to the rate of illness was higher in this age group. The drugs have been used unsafe and inappropriately. Antibiotic overuse was 68.04%. 10.28% of illness persons have used corticoids, while a few persons used traditional medication, pain killers and antipyretics for illness.
Pharmaceutical Preparations ; Residence Characteristics