1.Synthesis, structure and biological effects of some compounds of 2-mecaptobenzothiazole
Pharmaceutical Journal 1998;272(12):14-16
Nine compounds derivated from 2-mercaptobezothiazole were synthesized. Their structure have been identified by MS-, IR-, and UV- spectroscopy. Antimicrobial activities of some compounds have been tested. Hydrazide BT6 and substituted hydrazides BT7, BT8, BT9 were found to have significant inhibitory activity on P. aeruginosa, S. aureus, Asp. niger and F. oxysporum at concentration 50mcg/ml.
Pharmaceutical Preparations
2.Evaluation of drug myocardial toxicity and biological activity by real time xCELLigence analysis: a review.
Xu ZHANG ; Ruiying WANG ; Rongchang CHEN ; Lijiao XU ; Xiaobo SUN ; Miao YU ; Guibo SUN
Chinese Journal of Biotechnology 2021;37(7):2425-2434
Realtime xCELLigence analysis (RTCA) is a new cell detection technology to continuously monitor, record and analyze a variety of information generated by cell activity. In drug research, it plays an important role in assessing myocardial toxicity and cell biological activity. Here, we first introduce the underlying mechanisms and characteristics of RTCA. Then we review the applications of RTCA in the research of myocardial toxicity and cell biological activity, to provides the fundamental baseline for understanding and exploiting RTCA. With the real-time, unlabeled, non-invasive, high throughput, and high accuracy features, RTCA not only promotes drug research and development, but also has a broad and good application prospect in other fields.
Pharmaceutical Preparations
3.Choice of pharmaceutical services in Tien Son district
Journal of Medical and Pharmaceutical Information 1998;(1):24-27
According to the results of an investigation on 270 households in May 1999 carried out in Tien Son district, Bac Ninh province, 56 (20.79%) purchasing households came to commune health centre, 195 (72.22%) came to private clinic, 8 (2.96%) came to public pharmacy and 11 (4.03%) came to private pharmacy. Quality of the drug, easiness to access, reasonable price, good counseling... are the favorable factors to promote the purchaser's choice
Pharmaceutical Preparations
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Pharmaceutical Services
4.Sustained release of diclofenac tablet formulation with hydrophilic matrix excipient
Journal of Medical and Pharmaceutical Information 2004;0(2):25-28
Using the full quadratic model in drug dissolution optimization, the authors built up the sustained release of diclofenac tablet formulation with hydrophilic matrix excipient. The sustained excipient releases xanthan gum which has good features such as controlling medical substance regularly, rubbing seed easily, covering tablet easily and compressed force with a little affect to the rate of medical substance release. This formulation can be applied in making up medicines with a wider scale. It is being tested its stability and evaluated its availability to apply in manufacture
Diclofenac, Pharmaceutical Preparations , Tablets
5.Study on optimization of the dosage technique of chlorpheniramine meleate in multi-component drugs by refratometry
Pharmaceutical Journal 2004;44(1):24-27
Chlorpheniramine meleate (CM) is a antihistaminic agent. Assay for chlorpheniramine meleate in the multi-component drugs by colorimetry method. A technique was proposed to increase the accuracy of the assay for chlorpheniramine meleate. The assay of the method is about 2%
Chlorpheniramine
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Pharmaceutical Preparations
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Colorimetry
6.Some preliminary comments in treating depression with electrical shock combined with symphathetic beta block drugs
Journal of Practical Medicine 2003;458(8):40-41
Using beta-blocker propranolone immediately after electric shock helped successful treatment in 2 female patients, 21 years old and 27 years old, who experienced schizophrenia (F20) and had treated by antidepressant drugs. After treatment, both of them were stable and only used drugs at median dose. After electric shock they ate and slept well, had stable behaviour, and pulse was 80-90 c/m. Patients discharged after 1 week
Depression
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Defibrillators
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Pharmaceutical Preparations
7.Investigation on possibility of drug liberation of ciprofloxacine tablets
Pharmaceutical Journal 2005;0(7):19-21
The capacity of dissolution of active component of the tablet of ciproflaxacin. 6 samples composing of 78 domestic and foreign ciprofloxacin tablet were tested. Results showed that 2 of 3 samples of domestic tablet did not meet the requirement for dissolution mentioned to USP XXIII, while the foreign tablets manifested a rate of dissolution higher than that of pharmacopea
Ciprofloxacin
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Pharmaceutical Preparations
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Tablets
8.Analytical process of active ingredients belonging to benzodiazepine group currently in HoChiMinh city
Pharmaceutical Journal 2004;0(9):16-18
Basing on common chemical reactions, thin layer chromato graphy, absouptive ultraviolet spectrum some parameters were determined for preparation containing benzodiazepine in HCM City. The efficiency of extraction of benzodiazepan in 6 self made sample: Rhino sweet drink, coca-cola, combined food, soya milk, 333 beer and urine. Results found 17 active substances of diazepine group in 131 specialities of commercial propriatary name in HCM City, where diazepam had accounted higher rate in narcotic intoxixation cases. In criminal cases involved in tranquillisant narcotics, the most common substance were diazepan, flunitrazepan, clonazepan, bromazepan, alprazolam, clorazepat, oxazepan and nor-diazepan
Benzodiazepines
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Pharmaceutical Preparations
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Chemistry
9.Research on the effects of Weitai 999 in treatment of chronic gastritis
Journal Reasearch of Vietnam Traditional Medicine and Pharmacy 2004;0(12):18-23
The opening, comparing results before and after treatment clinical trial was performed to abserve the effects of Weitai 999 (an oriental medicine imported from China) on 60 patients with chronic gastritis, were treated by 500 mg of Weitai 999, 4 tablets a day for 30 days. The results showed that 81.2% of patients did not have upper abdominal pain. Endoscopy showed 71.7% of patients had not gastric mucosal inflammation after treatment. Histopathology showed good effect on activity of inflammation in 75.4% of patients. The rate of HP eradication was 34.5%. There was not clinical side effects
gastritis
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Therapeutics
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Pharmaceutical Preparations
10.Study on influe of artesunat on the reproductive progress in white mice
Pharmaceutical Journal 2004;336(3):14-17
Artesunat at doses of 50 mg/kg the first day and 25 mg/kg per day for four following days had no effect to the birth progress of P, F1 and F2. Concretely: No coffuse birth: ratio of conjugation, conception, early died feotus and late died feotus among P, F1 and F2 were similar, and were not higher than control group. No innate defects in born mice from P, F1 and F2. Quantity and weight of mice were in normal, and were not different with the control group
Artemisinins
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Pharmaceutical Preparations
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Therapeutics