1.The Management of Postterm Pregnancy : A Clinical Study of Induced Labor.
Sang Wook PARK ; Nam Su KIM ; Dae Jin KIM ; Chun Su LYU ; Sang Hyuk LIM
Korean Journal of Perinatology 2000;11(2):185-190
No abstract available.
Female
;
Labor, Induced*
;
Pregnancy*
2.Comparison of labor induction effect of misoprostol versus oxytocin
Journal of Medical and Pharmaceutical Information 2003;0(5):33-36
A randomised controlled clinical trial was performed on 180 pregnant women with indications for labour induction who were divided into 2 groups. Groups 1: each pregnant woman received 50 μg intravaginal misoprostol every 4h (total 250 μg). Group 2: intravenous oxyticin to induce the labour. The successful rate of misoprotol group was 89,89%, higher than oxytocin group- 70%. The interval from induction to vaginal delivery was longer in misoprostol group (8,47± 2,85h verus 6,45± 2,64h)
Labor, Induced
;
misoprostol
;
Oxytocin
;
3.Comparison of intravenous oxytocin infusion versus intracervical dinoprostone followed after 6 hours by intravenous oxytocin infusion for labor induction in prelabor rupture of membranes: A randomized controlled trial
Maria Ines A. Garcia ; Leah Socorro N. Rivera
Philippine Journal of Obstetrics and Gynecology 2020;44(2):1-8
Background:
A prolonged interval from prelabor rupture of membranes to delivery is associated with an increase in the incidence of maternal and neonatal morbidities and mortality. Various agents have been tested to improve the cervical Bishop score to expedite the delivery of the fetus and lessen the maternal and neonatal complications.
Objective:
To compare two protocols for labor induction in pregnant women with prelabor rupture of membranes (PROM).
Population:
Subjects were recruited from the University of Santo Tomas Hospital (Private Division and Clinical Division). Pregnant women with a live, term, singleton fetus, cephalic presentation, a reactive Non stress test, who presented with PROM and a Bishop score of ?5, with no previous Cesarean section, or other uterine surgery.
Methodology:
This is a two-arm superiority, open label, randomized controlled trial. Pregnant women with a live, term, singleton fetus, cephalic presentation, a reactive Non stress test, who presented with PROM and a Bishop score of ?5, and with no previous Cesarean section or other uterine surgery were randomly assigned to receive either intravenous (IV) oxytocin infusion or intracervical dinoprostone 0.5 mg gel followed 6 hours later by IV oxytocin infusion.
Results:
Vaginal delivery within 24 hours of labor induction increased significantly with intracervical dinoprostone gel followed by IV oxytocin infusion (87% versus 61%; RR: 1.43; 95% CI: 0.99 – 2.06; P<0.044). Comparable result was observed for nulliparous women included in the study population. The time interval from labor induction to active phase was significantly shorter in the dinoprostone-oxytocin group than in the oxytocin alone group (2.4 ± 2.1 versus 6.3 ± 1.4 hours; p<0.001). The time interval from labor induction to delivery was also significantly shorter in the dinoprostoneoxytocin group (6.3 ± 1.5 versus 10.4 ± 1.4 hours; p<0.000). Cesarean delivery rates were statistically similar in the dinoprostone-oxytocin and oxytocin alone groups (17% versus 40%; p=0.102). The neonatal outcomes were comparable in both groups, except for birth weight.
Conclusion
Intracervical dinoprostone 0.5 mg gel followed 6 hours later by an oxytocin infusion in term women presenting with PROM and an unfavorable cervix (Bishop Score of 5 or less) was associated with a higher rate of vaginal delivery within 24 hours, shorter time interval from labor induction to active phase of labor, and shorter time interval from labor induction to delivery, and no difference in maternal and neonatal complications was observed compared with oxytocin infusion alone.
Dinoprostone
;
Oxytocin
;
Labor
;
Induced
4.Neuraxial analgesia: a review of its effects on the outcome and duration of labor.
Korean Journal of Anesthesiology 2013;65(5):379-384
Labor pain is one of the most challenging experiences encountered by females during their lives. Neuraxial analgesia is the mainstay analgesic for intrapartum pain relief. However, despite the increasing use and undeniable advantages of neuraxial analgesia for labor, there have been concerns regarding undesirable effects on the progression of labor and outcomes. Recent evidence indicates that neuraxial analgesia does not increase the rate of Cesarean sections, although it may be associated with a prolonged second stage of labor and an increased rate of instrumental vaginal delivery. Even when neuraxial analgesia is administered early in the course of labor, it is not associated with an increased rate of Cesarean section or instrumental vaginal delivery, nor does it prolong the labor duration. These data may help physicians correct misconceptions regarding the adverse effects of neuraxial analgesia on labor outcome, as well as encourage the administration of neuraxial analgesia in response to requests for pain relief.
Analgesia*
;
Cesarean Section
;
Female
;
Humans
;
Labor Pain
;
Labor, Obstetric
;
Pregnancy
5.The effect of the walking epidural technique on maternal pain relief and the progress of labor in nulliparous patients: A randomized controlled trial comparing the effects of standard epidural analgesia and the combined spinal epidural analgesia techniques for labor
Cruz Ma. Concepcion L. ; Yoro Hipolito Arthur I. ; Zamnudio Rolando ; Garces Dennis
Philippine Journal of Anesthesiology 2002;14(1):1-8
Background: While the standard lumbar epidural analgesia technique has often been described as the gold standard for pain relief during labor, its disadvantages of delayed onset and the presence of motor blockade to a certain degree pose several constraints to pain burdened mother who also may not want to be confined in the supine position during the entire labor process. An alternative which may address these issues is the combined spinal epidural or walking epidural technique. We embarked on this study to compare both techniques in terms of onset and degree of analgesia and the outcome of labor.
Methods: Eighty (80) nulligravid ASA 1-2 term patients were randomly assigned to receive labor pain relief either using the standard continuous lumbar epidural analgesia (CLEA) using .125 percent bupivacaine with fentanyl or the combined spinal epidural analgesia (CSE) technique using intrathecal fentanyl and bupivacaine followed by bupivacaine boluses with fentanyl as needed. Outcome measures studied were Visual Analogue Pain Scores, onset degree and duration of pain relief and the progress and outcome of labor including neonatal outcome. Side effects were also noted.
Results: Very significant was the rapid onset of action, denser, and longer duration of pain relief in the CSE group. Likewise a faster rate of cervical dilation resulting in a shorter first stage of labor was noted. Second stage duration and mode of delivery in both groups however did not differ significantly. Maternal satisfaction during the first stage was greater in the CSE group, although overall maternal satisfaction was comparable in both groups. Pruritus, although a significant occurrence in the CSE group did not need any intervention for treatment. No adverse effects on both the neonate and mother were noted.
Conclusion: Based on the results of our study, the CSE or walking epidural is a encouraging alternative to laboring mothers, especially those in severe pain requiring rapid and profound relief. Our results show that compared the standard epidural technique, it hastens the rate of first stage labor - but whether ambulation plays a significant role in this aspect needs to be further investigations
Human
;
LABOR PAIN
;
OBSTETRIC LABOR
;
ANALGESIA, EPIDURAL
;
PAIN
6.Real situation of obstetric complications in the community in some communes of Hoai Duc district, Ha Tay province.
Vinh Quang Dao ; Mai Thi Phuong Tran ; Dien -- Vu
Journal of Medical Research 2007;52(5):57-63
Background: Obstetric complications always are the risk factors which impact on pregnant women, especially no having care and treatment on time. Objectives: (1) To determine the rate of obstetric complications in some communes of Hoai Duc district, Ha Tay province. (2) To identify some factors which may have impact obstetric complications in the community. Subjects and method: Conducting a cross \ufffd?sectional survey with 363 women randomly chosen for sampling from the list of 1.530 women of reproductive age having terminated their pregnancy dressed for a six \ufffd?month period (from 1 October 2004 to 31 March 2005) in 10 communes of Hoai Duc district, Ha Tay province. Results: The obstetric complications rate was 9.9%. Obstetric complications recorded under the research often had the following forms: hemorrhage (94.4%), infection and pre \ufffd?eclampsia/eclampsia, each of them (2.8%). obstetric complications regularly happened with women of over 40 years old (20%). Those complications were closely linked to vaginal bleeding symptom during pregnant period with p<0.05. Conclusion: Obstetric complication rate was 9.9%, mostly hemorrhage. There was close relation between obstetric complication with vaginal bleeding symptom during pregnant period.
Obstetric Labor Complications
;
Residence Characteristics
;
7.Study on the tocolysis effectiveness of nifedipin on uterine contraction in the management of preterm labor
Journal of Medical Research 2005;36(3):44-52
A clinical trial was performed to evaluate the tocolytic possibility of nifedipin and to propose a treatment regimen for preterm labor in the National Hospital of Gynecol-Obstet from July 2003 to December 2003. There were 40 cases of preterm labor with gestational age 31 weeks and 3 uterine contractions per minute on average. Patients received a 10 mg sublingual loading dose every 20 minutes (maximum dose 40mg), and followed by 20 mg oral dose every 6- 8 hours. Result: the effectiveness in tocolysis of nifedipin is very fast. It took 60-80 minutes to arrest uterine contraction (70- 80%) (including contractions of high frequency and intensity), especially in urgent tocolysis. The lower the frequency and intensity is, the higher and sooner the effectiveness is. 92.5% of delivery were delayed for 48 hours. 82.85% were postponed until 36 weeks, and the mean time of prolonged pregnacy was 39 days. Side-effects were mild and transient and in normotensive pregnant women blood pressure was almost unaffected. This treatment regimen of nifedipin showed the effectiveness in preterm labor. In brief, nifedipin is an effective, safe, convenient and economic tocolytic agent. It may well represent the best suitable tocolytic alternative currently available and can be used widely in Viet Nam.
Obstetric Labor, Premature, Nifedipine, Tocolysis
8.Misoprostol in faciliting the cervical dilatation for vacuum aspiration to terminate the pregnancy
Journal of Medical and Pharmaceutical Information 2003;0(5):37-39
From Dec. 2003 to Feb 2004, 90 women of 6-12 week pregnancy received 100 μg intra vaginal misoprostol 3 hours before intervention at central Hospital of Ggn. and Obst. 96,67% had got success, with the mean cervical dilatation of 8,1± 0,92mm. Side effect manifested in 2,2% of patients
Misoprostol
;
pregnancy
;
Labor Stage, First
10.Comparative trial of combination therapy of indomethacin and ritodrine versus single therapy of ritodrine for the premature labor.
Ji A RYU ; Kyung Soon LEE ; In Ok SONG ; Young Ju KIM ; Jong Il KIM ; Han Ki YOU ; Jung Ja AHN ; Bok Hee WOO
Korean Journal of Perinatology 1993;4(3):349-357
No abstract available.
Female
;
Indomethacin*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*