1.A Clinical Study on Herpes Zoster and Chicken Pox.
Jin Woo KIM ; Si Yong KIM ; Kang Woo LEE ; Won HOUH ; Ock Ja CHO ; Seung Won LEE
Korean Journal of Dermatology 1982;20(1):69-76
The purpose of this study was to elucidate the epidemiology and the clinical characteristics of herpes zoster and chicken pox. 703 patients with herpes zoster and 237 patients with chicken pox who were seen at the Department of Dermatology, St. Marys Hospital during 8 years were taken for this retrospective study. Both groups of the patients were evaluated in regard to annual, seasonal and monthly incidence, age incidence and sex ratio. Patients with herpes zoster were further assessed concerning associated conditions, dermatomic distributions and complications. The results were as follows, 1. The annual rate for chicken pox ranged from 0.03% to 0.18% (mean 0.13%) and revealed no epidemics, however, its incidence was higher in early summer and winter. There was no sexual difference. Chicken pox was seen most. frequently in the 0-9 year age group (91.1%). 2. The annual rate for herpes zoster ranged from 0.23% to 0.52% (mean 0.38%). There were no significant annual, seasonal and monthly variations, and there was a. equal sex ratio. Herpes zoster was seen most frequently in the 50-59 year age group (19.1%) 3. The frequencies of the associated conditions in herpes zoster, in descending order, were infectious disease (2. 7%), diabetes mellitus (2.3%), malignant neoplasm(1. 4%), immunosuppressive drug (l. 4%), autoimmune disease (0.6%), and radiation therapy (0.4%). 4. The dermatomic involvement of herpes zoster was most frequent on thoracic dermatome (53.5%) and others were cervical (16.5%), lumber (10.1%), ophthalmic branch of trigeminal nerve (8.8%), sacral (1.6%), maxillary branch of trigemenal nerve (1.3%), mandibular branch of trigemical nerve (0.6%) and facial nerve dermatome (0.1%). The incidence of involving two different dermatomes was 2.9% and was most common on cervicothoracic dermatome (1.8%). However, one case of cervico thoracic dermatome showed bilateral involvement. 5. The most common complication of herpes zoster was postherpetic neuralgia (6.5%) and others were secondary bacterial infection (2.6%), keratoconjunctivitis (0.6%), keloid formation (0.3%), generalized varicelliform eruption (0.1%), Ramsay-Hunt syndrome (0.1%) and recurrent herpes zoster (0.1%). The mean age of incidence for postherpetic neuralgia was 58.4 years and its incidence was the highest over 70 years (39.5%). Postherpetic neuralgia was most frequently seen in the involvement of ophtalmic branch of trigeminal nerve.
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2.A Statistical Study of Dermatoses (1971 - 1980).
Kee Seok HUH ; Jong Bong KAHNG ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1982;20(1):59-67
The statistics of 40,611 new cases of skin diseases seen in Dermatologic department of Chonnam University Hospital from 1971 to 1980 are analysed and significant changes in incidence of the 25 most common dermatoses are discussed in detail and the results are comared with other surveys. The results of this study are summed up in 4 tables. Table 1. Shows the annual frequency of the 25 most common dermatoses. Table 2. Shows the frequency of the 25 most common dermatoses by age group. Table 3. Shows the frequency of the 25 most common derrnatoses by season, sex and region. Table 4. Shows the comparison of frequency of the 20 most common dermatoses with other reports.
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3.Study on Establishment of Disease Database and Query System Through Internet Using Uniform Hospital Discharge Data Sets.
Yoo Kyung PU ; Kwang Hwan KIM ; Sun Won SEO ; Jin Sook SUH ; Mi Jeong KIM ; Jung Don SEO ; Seok Jun YOON ; Young Sung LEE ; Moo Sik LEE
Journal of Korean Society of Medical Informatics 2002;8(3):19-26
It is necessary to have accurate statistical data of disease for planning and evaluating public health policy as well as assessing population health index. The national health insurance data is the only data to assess incidence of diseases nation-wide. However, inaccuracy of the data pose serious limitations of use of the data. The Medical Record Departments of individual health facilities have used discharge summary information for hospital management and clinical research, but a nation-wide integrated database of diseases has not been setup and utilized. We applied previously developed Korean Uniform Hospital Discharge Data Sets to collect discha rge summary data from health care facilities and establish integrated database. We also made the question and answer column about disease of the database in the internet. We collected patient discharge data from a tertiary-care hospital for one year using the electronic discharge summary data collection system, except for health care costs. The internet querying system provided optional selection of columns or rows, individual and/or disease groups and surgical procedures. To make query easy, the system provided various functions like querying codes of diseases and/or surgical operations, reviewing questions, downloading results via excel files, help functions of query. The establishment of disease database and the interactive system through internet is in its inception, further studies may be necessary to make it a user friendly and accurate system. There is a need of an accurate assessment of current population-based health status and future trends in Korea. It is hoped that this study may trigger to establish national accurate database for enhancing studies of health policy making, clinical research and vital health statistics by expanding data collections to the se condary- care and primary- care institutions.
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4.Study on the Anti-Smooth Muscle Antibody and Anti-Nuclear Antibody of Chronic Active Hepatitis, Chronic Persistant Heratitis and Liver Cirrhosis in Korea.
Kap No LEE ; Seung Yong PAIK ; Sang Kook LEE
Korean Journal of Pathology 1986;20(2):147-156
In Korea chronic liver diseases are the important medical issues because of their high incidence, poor prognosis and no available therapeutic resume. It is believed that the etiologic agent of most of chronic liver diseases in Korea is hepatitis B virus. To find out the incidence of positivity and to understand the autoantibodies in some of the chronic liver diseases in Korea, anti-smooth muscle antibody and anti-nuclear antibody tests were performed on 43 patient serum with chronic active hepatitis, 13 patient serum with chronic persistant hepatitis and 20 patient serum with liver cirrhosis, who diagnosed by liver biopsies. The results of the study are summarized as follows: 1) The positivity of anti-smooth muscle antibody in chronic active hepatitis was 93.0%, that in chronic persistant hepatitis 60.0% and that in liver cirrhosis 80.0%. 2) The positivity of anti-nuclear antibody in chronic active hepatitis was 18.6%, that in chronic persistant hepatitis 15.4%, that in liver cirrhosis 5.0%. 3) The test efficiency of anti-smooth muscle antibody to differentiate chronic active hepatitis from chronic persistant hepatitis and liver cirrhosis was 48.7%. The above results suggest that the antismooth muscle antibody may be related to the "necrosis of liver cells", and further studies are needed to fine out any relationship between the autoantibody and the disturbance of immune regulatory function if there is, as this study suggested.
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5.Empty sella: incidence and significance in MR.
Young AHN ; Hyun Sook HONG ; Jae Sung PARK ; Dae Ho KIM ; Hae Kyung LEE ; Moo Chan CHUNG ; Deuk Lin CHOI ; Ki Jung KIM
Journal of the Korean Radiological Society 1991;27(6):773-777
No abstract available.
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6.Two Cases of Congenital Renal Hypoplasia.
Jun Ho CHANG ; Oh Tac WHANG ; Tae Eun CHOUNG ; Kwang Soo JUN ; Eung Jib KWAN
Korean Journal of Urology 1971;12(4):409-412
The incidence of congenital unilateral renal hypoplasia is extremely rare.Two cases of congenital unilateral renal hypoplasia were presented with review of literature.
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7.Alcoholic Liver Cirrhosis with Multiple Pulmonary Consolidations.
Young Soo AHN ; Sang Moo LEE ; Jong Eun JOO
Tuberculosis and Respiratory Diseases 2002;53(1):79-84
Pulmonary nocardiosis is an infrequent but severe infection due to the microorganism, Nocardia spp, which may behave as both an opportunists and as a primary pathogens. Usually nocardiosis is found in patients under immunosuppressive regimens for organ transplans, chemotherapy for a malignancy and corticosteroids. The experience of pulmonary nocardiosis in the medical literature is limited to just case reports, with a few series including extrapulmonary nocardiosis. It is believed that the incidence of this infection has been increasing since 1960. The diagnosis is difficult because of the nonspecific clinical manifestations, the lack of laboratory evidence, and the non-specific radiographic findings. Here, we report a case of pulmonary nocardiasis in a 66 year-old patient with alcoholic liver cirrhosis who has suffered from acutely developed dyspnea and general edema. The nocardia species. was cultured from a specimen obtained by a percutaneous transthoracic needle biopsy.
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8.Low-grade Immature Teratoma of the Ovary with Gliomatosis Peritonei: A case report.
Korean Journal of Pathology 1994;28(3):322-324
Immature teratoma accounts for less than I percent of all ovarian teratomas and occurs commonly in young individuals, the peak incidence being in the second decade. It contains a variable mixture of mature and immature tissues in which neuroectodermal elements almost always predominate. Gliomatosis peritonei, miliary implants of mature glial tissues on the peritoneum or omentum, is an infrequently reported complication of mature or immature ovarian teratomas. We describe the first case in Korea of a 12-year-old girl with an immature teratoma and numerous glial peritoneal implants.
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9.MR Findings of the Intraventricular Tumors.
Ji Hoon SIN ; Ho Kyu LEE ; Hyun Jin KIM ; Chang Jin KIM ; Soo Mee LIM ; Myung Joon LEE ; Choong Gon CHOI ; Dae Chul SUH
Journal of the Korean Radiological Society 1998;38(6):993-999
With regard to various pathologic conditions, it is important to understand not only MR findings, which dependon the anatomic location of intraventricular lesions, but also the anatomic location most appropriate for surgicalintervention. In this paper we will analyze and demonstrate the incidence and characteristic MR findings ofvarious intraventricular tumors according to the location of ventricles.
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10.Histotopographic Observations on Metaplastic Changes of the Gallbladder Mucosa.
Eun Sil YU ; Yong Il KIM ; Sang Kook LEE
Korean Journal of Pathology 1985;19(1):58-66
Fifty three surgically resected gallbladders(49 cases of chronic cholecystitis with or without cholelithiasis, 4 cases of incidentally resected gallbladders) and 14 autopsy cases were subjected to the histotopographic analysis to identify the nature and distribution of metaplastic mucosal changes, and to determine the possible histogenesis of these mucosal lesions and diagnostic implication as a parameter of chronic cholecystitis. 1) Antral type glands were demonstrated in 47(88.7%), goblet cells in 19(35.8%) and surface epithelial changes in 27(50.9%) of total surgical specimens, indicating the benign metaplastic changes of the gallbladder mucosa toward the gastric or intestinal type. 2) Topographic distribution illustrated the extension of antral type gland to the middle and upper one third portions of the gallbladder mucosa in 37 cases, each. Goblet cells in the middle and upper one third of the mucosa were demonstrable in 13 cases(68%) an 8 cases(42%), respectively. 3) Average age by degree of extension was 50.0 years in Grade O-I, 50.1 years in Grade II and 56.4 years in Grade III. 4) Among 53 surgically resected gallbladders, gallstone was found in 31 cases, in which was a significant correlation between the distribution of metaplastic changes by degree of extent and cholelithiasis. 5) There was no statistical significance between incidence of metaplastic changes of the gallbladder and degree of inflammatory reaction by means of chronic and/or acute inflammatory cell infiltration and Rokitansky-Aschoff sinus formation. 6) Only two out of fourteen autopsy cases demonstrated focal and spotty presence of goblect cells. It is of authors assumption that the lining epithelium of the gallbladder undergos various types of metaplastic changes in the diseased conditions, in which cholelithiasis is included as one of preceding factor. And also, the diagnostic implication of epithelial metaplasia as an expression of chronic cholecystitis is discussed.
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