1.The correlation between preoperative serum GGT level and the prognosis in liver cancer patients undergoing living donor liver transplantation
Shangkun CAI ; 广西壮族自治区河池市人民医院普通外科 ; Li JIANG ; Jiayin YANG
Chinese Journal of General Surgery 2017;32(11):945-948
Objective To explore the relationship between the serum gamma glutamyl transpeptidase (GGT) level and the prognosis of liver cancer patients undergoing living dornor liver transplantation.Methods A retrospective analysis was made on 139 liver cancer cases receiving living donor liver Tx from Apri 2005 to Oct 2015 in Sichuan University Huaxi Hospital.GGT cut-off value of 71 U/L was calculated from the ROC curve method (sensitivity was 72.2%,specificity was 59.0%).According to the values of the cut-off patients were divided into high GGT group (73 cases) and low GGT group (66 cases),chi-square test was used to judge its correlation with capillary tumor emboli and Kaplan Meier method to determine the overall survival rate difference.Results The tumor vascular invasion,AFP level,tumor size were in disfavour for higher GGT group (P <0.05).The 1,3,5 year's survival rates were 59.0%,44.5%,39.7%,for high GGT group,and in low GGT group it was 78.6%,63.6%,63.6%,P =0.010).Conclusions The liver cancer patients with high preoperative serum GGT values have poor long-term prognosis after receiving living donor liver transplantation.
2.Clinical application of laparoscopic combined with choledochoscopy for choledocholithotomy and primary suture
Qinglu HUANG ; Hongfei LI ; Liju HUANG ; Kezeng HUANG ; Yu MO ; Qiang QIN
China Modern Doctor 2019;57(10):45-49
Objective To investigate the feasibility and safety of laparoscopic combined with choledochoscopy for choledocholithotomy and primary suture. Methods 82 patients who underwent laparoscopic combined with choledochoscopy for choledocholithotomy and primary suture from Hechi People's Hospital from June 2016 to August 2018 were enrolled as study objects. They were divided into study group and control group according to the different treatment methods of common bile duct incision. 40 patients in the study group underwent primary suture of the common bile duct and 42 patients in the control group underwent T-tube drainage. The surgical outcomes and complications of the 2 groups were compared. Results All the patients in the two groups were operated smoothly and there were no cases of conversion to open surgery. The operation time, intraoperative blood loss, postoperative ambulation time, time of removal of abdominal drainage tube, and hospitalization time were lower in the study group than those in the control group, but the difference was not statistically significant (P>0.05). The incidence of electrolyte disturbance, postoperative recovery time, and hospitalization cost in the study group were lower than those in the control group, and the difference was statistically significant (P<0.05). The incidence of surgical complications in the study group was lower than that in the control group, but the difference was not statistically significant (P>0.05). Conclusion Laparoscopic combined with choledochoscopy for choledocholithotomy and primary suture in the treatment of intrahepatic and extrahepatic bile duct stones has good curative effect, rapid recovery, less internal environment disorder and low hospitalization cost. It is safe and feasible.