1. STUDY OF THE DRYING TECHNOLOGY FOR
Нармандах Э. ; Мөнхжаргал Н. ; Хүрэлбаатар Л.
Mongolian Pharmacy and Pharmacology 2014;5(2):3-5
Introduction: Throughout the world, there are a number of plants that have been identified with immune boosting ability and the following plants Salsola laricifolia Turcz, Inula helenium that have been proven to support the immune system and grow in Mongolia were selected for a phytochemical study and prepared technology of dried powder.Goal: To develop dry extract technology with immunity stimulating action from natural plant sources.Material and methods: A biological active substance coumarin and flavonoid determination byspectrophotometer.Result: Total coumarin in raw material of Salsola laricifolia was 2.9±0.03%, total flavonoid amount was 1.66±0.021%, total polysaccharide was 3.83±0.025%, humidity was 5.7±0.01%, extractive substance amount was 20.63±0.91% ( p≤0.05). Total polysaccharide in raw material of Inula helenium was 20.78±0.03%, humidity was 6.03±0.03%, extractive substances amount was 21.76±0.23.Salsola laricifolia’s polysaccharide content was the highest or 0.19±0.031%, when extracted with 30% ethanol the flavonoid content was 0.36% when 25%, 30% ethanol was used as the extragent, 30% ethanol is determined to be an appropriate extragent. Inula helenium’s water extract contained 3.75±0.05% polysaccharide, 0.43±0.005% flavonoid. 50% alcohol extract had a 3.20±0.01% polysaccharide, flavonoid content of 0.25±0.01% and water extragent is determined to be proper extragent in future research.The scheme of dry extract preparation technology was developed and determined quantitative indication. Total polysaccharide which was active substance of Salsola laricifolia’s 30% ethanol and microcrystal cellulose under 15:1 version was highest in 0.46±0.011% and total polysaccharide which was active substance of Inula helenium water extract and microcrystal cellulose under 10:1 version was highest in 3.46±0.021% that`s why, it is suitable to dry extracting Salsola laricifolia’s 30% ethanol and microcrystal cellulose under 15:1 version, Inula helenium water extract and microcrystal cellulose under 10:1 version.Key word: Inula helenium, Salsola laricifolia, immunity support, dry extract