Introduction: The medicine market is the rapidly developed, but the following negative consequences are faced with the field. Today, 42 drug factories, 158 drug supply centers and more than 1.200 drugstores conduct their services in our country and 543 of the total drugstores are located in Ulaanbaatar city. Total 2.476 medicines with or without prescription are sold through the drugstores. As of December 2011, 78.8% of total medicines, entered to the registration are the medicines which must be issued with the prescription. Goal: Discovering the reasons issuing the prescription medicines without the prescription among the drugstores of Ulaanbaatar city. Materials and method: • Legal documents on making the medicine prescription • Prescription, provided by doctors • Questions for doctors • Questions for pharmacists • Questions for the users Total 60 pharmacists of the 42 drugstores, 30 doctors of the Health Centers and Family Hospitals of Songinokhairkhan, Bayanzurkh, Chingeltei and Sukhbaatar district, Ulaanbaatar and 321 users who were served by the 30 drugstoresattended in the research work. The first questionnaire was provided on March 20-28, 2012 and subsequent questionnaire was made on October 18-30, 2012. The survey estimating the standard measurement on the doctor’s medicine prescription was carried out and I had worked on the 500 prescriptions, collected from the drugstores on March 2012 for a week. Results: As the result of this research work, 39.5% of total users who attended in the research work answered that there were high loads to take the medicine prescriptions, 31.6% of them answered that theywere busy to go to the doctor due to hospital high loads and 41.5% of doctors answered that they did not write the prescription when high loads. 78.3% of the pharmacists who attended in the research answered that their customers did not have the prescriptions. 32.6% of the prescriptions, attended in the research were not registered in the prescription form and 17.1% of the doctors answered that prescription forms were not enough. As the total prescription mistakes, name of patient was written wrong (31.4%), the diagnosis was not written (68.8%), medicine dose was written wrong or not written (31.4%), the usage instructions were not written /26.2%/, name of hospital was not written /73.2%/, doctors did not sign /52.2%/ and date of prescription was not noted /54.0%/.