Background: Health statistics show that cardiovascular disease are the one of 5 leading causes of mortality per 100,000 populations are and it has been increasing continuously (Health indicators 2014 of Mongolia). The Mongolian model list of essential medicine had published first time in 1991, since adoption of the treatment this model list, it has updated 7 times (1993, 1996, 2001, 2005, 2009, 2015). The comparable study between World Health Organization (WHO) model list of essential cardiovascular medicines and Mongolian model list of essential cardiovascular medicines not published yet. Good pharmaceutical management is an important approach to contain the increasing expenditures on medicines in developing countries. ABC and VEN analysis classify items according to their budgetary consumption and importance, respectively. When the two are combined together they increase efficiency in medicines supply chain systems and also diminish costs associated with overheads, wastages and inefficiencies. Few number of studies for pharmaco-economic analysis ABC/VEN in medicines have published in Mongolian (Guldana.Kh., 2011, Oyuntsetseg.G., 2012, Munkhtuya.B., 2012, Mamedova.S.E., 2010, Ziganshina.L.E., 2007, Alimenko.M.A 2010), but does not have any article of study pharmoco-economic analysis ABC/VEN of cardiovascular medicines in Mongolia. Aim of study: To study of cardiovascular medicines in second and tertiary hospital by pharmacoeconomic analysis ABC/VEN Materials and Methods: We have studied cardiovascular medicines list procured in Central Agency for Procurement of Mongolia (2014). Data were collected using pre-tested questionnaires and through document reviews. Analysis was performed by using Russian Pharmcompail 6.1.1 program, excel spreadsheet and SPSS version 17.0 computer software. Result: About 97 cardiovascular medicines were procured during the last financial year 2014 in 38 secondary level hospitals and tertiary hospitals. ABC analysis shows that, 19 (19.59%) medicines were found to be class A, while class B had 24 (24.74%) items whereas class C consisted of the remaining 54 (55.67%) medicine items and consumed 1.117.049.036 MNT (73.89%) in class A, 284.221.954 MNT (18.80%) in class B and 110.542.688 MNT (7.31%) in class C. Of the Heparin injection (5 000 IU) alone contributed 312.000.000 MNT (27.9%) of the class A. There was no special inventory control methods for class A items which are main drivers of medicine expenditures. ABC analysis provides an accurate and objective picture of budget expenditures on medicines. VEN-analysis helps to prioritize between various medicines in their selection for procurement and use within a drug supply system. We have found that 22 (22.68%) of the items included to Vital category, 62 (63.92%) to Essential category and 13 (13.40%) included to Non-essential category. The study showed Captopril 25mg, No-spa 40 mg, Cinnarizine 25mg, Cavinton 5mg, Validol 0.06gr, Adelphan 40 mg, Papaverine hydrochloride, Nimodipine 30mg, Dicynone 250 mg, Oxybral 30 mg, Captopril HCT, Phlebodia 600mg were not listed in Mongolian model list of essential medicines. About 13 medicines (90.812.055 MNT) were Non-essential and costing approximately 6.01% of the budget equivalent to 1.5 billion. It was interesting to find that more than half of the Vital, Essential and Non-essential medicines were lowest cost items belong. The hospital could have tried to minimize purchase of the Non-essential medicines and increase the amount of the Vital items since these are for life saving purpose. Conclusions 1. The ABC analysis notified that 20.65% of 1.117.049.036 MNT of the total budge in A class consumed to medicine affecting anti coagulation (Heparin 5 000 IU) injection accounting treatment of ischemic heart disease. The Streptokinase expenditure listed in Mongolian model list of Essential medicines was low (0.29%). 2. The study showed Captopril 25mg, No-spa 40 mg, Cinnarizine 25mg, Cavinton 5mg, Validol 0.06gr, Adelphan 40 mg, Papaverine hydrochloride, Nimodipine 30mg, Dicynone 250 mg, Oxybral 30 mg, Captopril HCT, Phlebodia 600mg were not listed in Mongolian model list of essential medicines. About 13 medicines (90.812.055 MNT) were Non-essential and costing approximately 6.01% of the budget equivalent to 1.5 billion. It showed that hospitals have possibility to change this portion of budget in to Essential category of medicines.

Background: An accurate assessment of LV function by determining the LV volumes and the ejec- tion fraction (EF) is important in evaluating the prognoses of patients with CAD. Strain by speckle tracking is evaluated by frame-by-frame tracking of the individual speckles throughout the cardiac cycle. This imaging technique discriminates between active and passive myocardial motion and enables angle-independent quantification of myocardial deformation in two dimensions. In-hospital heart failure during acute myocardial infarction is associated with adverse outcome. However, rela- tionship between left ventricular longitudinal myocardial mechanics and in-hospital heart failure with normal or mildly reduced left ventricular ejection fraction in patients with acute myocardial infarction is unclear. We hypothesized that speckle-tracking derived global longitudinal strain parameter is independent associated with in-hospital heart failure clinical criteria. Aim: To assess left ventricular function after drug eluting stent placement therapy of PCI in patients with myocardial infarction by Strain Imaging after myocardial longitudinal strain in patients with acute myocardial infarction. Material and methods: We prospectively included patients who presented acute myocardial infarc- tion and treated by primary PCI. In-hospital heart failure is defined by Killip class during admission. Multiple logistic regression analysis was used to reveal relationship between left ventricular global longitudinal strain and in-hospital heart failure. Separate multiple logistic regression model con- structed for patients with preserved left ventricular ejection fraction (LVEF≥55%). The incremental value of global longitudinal strain was tested by assessment of model c-statistics. Results: Total drug eluting stents were placed in 414 patients (mean age 60±13, 84% male) were included and 93 patients (22.5%) presented in-hospital heart failure Left ventricular global longi- tudinal strain (GLS) was significantly impaired in patients with in-hospital heart failure compared patients without in-hospital heart failure (-16.1±3.7 vs. -11.6±3.1, p<0.001). After adjustment of pos- sible predictor of in-hospital heart failure such as age, clinical, biochemical and echocardiographic parameters, global longitudinal strain was independently associated with in-hospital heart failure (odds ratio 1.32, 95% CI 1.16-1.50, p<0.001). In-hospital heart failure presented in 21 patients with LVEF≥55% and GLS is also significantly impaired in this group (-17.7±3.2 vs. -12.7±2.2, p<0.001).

Introduction: “Monos” pharmaceutical Institute purposed to prepare pharmacist by international pharmacist curriculum based on “The seven star pharmacist” Goal: The aim of Pharmaceutical education, scientific research and studies of “Monos” Institute is according to the classification defining rules of Mongolian higher educational some estimation. Materials and Methods: The study has been completed by procedure report of 2010-2012, annual statistic report dedicated to Minister of Education Science and Culture on Microsoft Excel. Results: Monos” Institute Pharmacy faculty have graduated 571 pharmacists 43 pharmacy technicians and 46 master of pharmacy so far since our pharmaceutical Institute was established. All of the alumni take the nationwide pharmacy license examination with succesful and now 97% of them are currently employed according to their professions. 80% of our graduators work for drug supply organizations and the rest of them work for pharmacies. Bachelor and Master degree candidates are totally 622. We have renewed our pharmaceutical 5 year bachelor degree curriculum 5 times since 2000. “Monos” pharmaceutical Institute’s 5 year bachelor pharmacist curriculum purposed to prepare “The seven star pharmacist” based on international pharmacist curriculum is 5 year academic subjects and basic, professional, and specialized study with 175 credits. Our scientists and lecturers published 900 studies, researches by the result of it we developed 22 standards, 3 products were patented, 15 products got certification of State Registration and 20 percents of the articles were published in foreign journals. It estimates our advancement. Conclusions: 1“Monos” Institute created the training-science-manufacturing environment during its development and provided to ensure the control of estimation, accreditation of institutes and colleges 2. Further adjusting Professional standard of Mongolian pharmacists, renewing the educational curriculum, cooperating the universities and institutes prepare pharmacists therefore we would be able prepare core curriculum for the pharmacist.