Abstract:In the recent years, The pharmaceutical manufacturers interest to natural medicines and biological active preparations from animal, plant and mineral raw materials. According to some sources, Plantago majus contains polysaccharides and aucubin. Some researchers investigated aucubin that is anti inflammation and antimicrobial activity. Many anti cough formulations that are contains Plantago majus sold in pharmaceutical market. For example: Herbion, Pectoral manufactured by KRKA, Naturwaen and Mepha, respectively.The aim of this study determination of aucubin and biological active substances in Plantago majus that is growth commonly in Mongolia.The result of this study, Plantago majus leaves are estabilished polysaccharide 4.66%. Leaves of Plantago majus has been extracted by water(1:5), water (1:10), 30 % sorbitol and 20% ethanol, then determination aucubin and polysaccharide. The results, polysaccharide was 4.12%, 3.46%, 0.336% and 2.65%, respectively. Aucubin was 2.88%, 3.44%, not determined 30% sorbitol extract and 1.88%, respectively.

Abstract:Currently, Mongolian 33 domestic pharmaceutical industries produce totaly of 364 different of drugs into pharm market, that includes 82% of the hard drug form of tablets, capsules, 14% of the liquid formulated drug form and 4% of the soft drug form. On the International pharmacopoeia articles such as Brithish pharmacopoeia have reported 11 types soft drug forms clearly. But, now in our national pharmacopoeia articles involved 3 types of soft drug form of cream, suppositorium, eye soft drug forms. So there are need to increase a number of soft drugs into national pharmacopoeia articles. Thus, we put our main goal is to make comperative study of national and international pharmacopoeia article of soft drug forms. This study will help to enter soft drugs in to National pharmacopoeia in the future.Keywords: Soft drug form, crem, supposi torium, eyes soft drug forms, Pharmacopoeia soft drug form articles.