1.Preliminary study on the occurrence of pten and PIK3CA gene mutations in endometrial cancer among Malaysian women
Subramaniam KS ; Wong MS ; Woo Yl ; Mat Adenan NA ; Mohamed Z ; Chung
Journal of University of Malaya Medical Centre 2013;16(1):1-5
Genetic mutations in endometrial cancer (EC) have been extensively studied in the Western population but
not much in Asian cohorts. This study has demonstrated that PTEN and PIK3CA mutations are commonly
found in EC among Malaysian women. Following RNA extraction from 20 cancerous and 18 non-cancerous
tissues, the presence of mutations in 9 exons of PTEN and 3 exons of PIK3CA genes were detected using realtime
PCR, accompanied by High Resolution Melt (HRM) analysis. Sequencing confirmed specificity of each
PCR product. The mutations for both genes were detected in the samples with varying frequencies. Notably,
all samples expressed mutation of PTEN at exon 7 but none in exon 4. Further analysis demonstrated that
strong concurrent mutations occurred between exons 7 of PTEN with exon 20 region 1 of PIK3CA gene (90%).
Our data showed mutations are present in EC and not the non-cancerous tissues. Larger samples are being
collected to validate this observation.
Uterine Neoplasms
2.Use of a cognitive computing system for treatment of cervical cancer.
Journal of Gynecologic Oncology 2017;28(5):e67-
No abstract available.
Uterine Cervical Neoplasms*
3.A Rare Complication in a Patient Irradiated for Cervical Cancer.
Intestinal Research 2013;11(4):323-324
No abstract available.
Humans
;
Uterine Cervical Neoplasms*
4.Studies of free radical scavenger enzymes in RBC from cervical cancer patients.
Byung Ok PARK ; Ha Jong JANG ; Hyuck JUNG ; Se Joon HAN
Korean Journal of Obstetrics and Gynecology 1991;34(6):804-810
No abstract available.
Humans
;
Uterine Cervical Neoplasms*
5.Clinical survey of 67Ga-citrate scan in staging for cervical cancer patients.
Kwang Hwy KIM ; Ju Hwa JIN ; Jae Hoon CHUNG
Korean Journal of Obstetrics and Gynecology 1992;35(3):349-358
No abstract available.
Humans
;
Uterine Cervical Neoplasms*
6.Retraction: Comparison of As2O3 and As4O6 in the Detection of SiHa Cervical Cancer Cell Growth Inhibition Pathway.
Yong Wook KIM ; Su Mi BAE ; Keun Ho LEE ; Joon Mo LEE ; Sung Eun NAMKOONG ; Insu P LEE ; Chong Kook KIM ; Jeong Sun SEO ; Jeong Im SIN ; Yong Wan KIM ; Woong Shick AHN
Cancer Research and Treatment 2007;39(1):47-47
No abstract available.
Uterine Cervical Neoplasms*
7.Time for global efforts with clinical trials for advanced cervical cancer patients.
Journal of Gynecologic Oncology 2009;20(4):201-202
No abstract available.
Humans
;
Uterine Cervical Neoplasms
9.Prognostic factors after radical surgery for stage Ib-IIa cervical cancer.
Suk Mo KIM ; Jae Doo YOO ; Byung Ryong KIM ; Young Sam CHOI ; Sung Il JUNG ; Chul Hong KIM ; Ho Sun CHOI ; Jee Soo BYUN
Korean Journal of Obstetrics and Gynecology 2000;43(8):1422-1430
No abstract available.
Uterine Cervical Neoplasms*
10.Cervical cancer in pregnancy.
Woo Sik LEE ; Chan Kyu PARK ; Dong Hee CHOI ; Jae Wook KIM ; Su Nyung KIM ; Tae Sik HWANG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1111-1119
No abstract available.
Pregnancy*
;
Uterine Cervical Neoplasms*
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