No abstract available.
Spermatogenesis*

No abstract available.
Aging* ; Humans ; Male* ; Spermatogenesis*

No abstract available.
Hydrocortisone* ; Spermatogenesis* ; Varicocele* ; Veins*

No abstract available.
Animals ; Finasteride* ; Rats* ; Spermatogenesis*

Animals ; Humans ; Male ; Spermatogenesis

AIMTo determine whether vasectomy away from the epididymal tail (via the inguinal canal) in rabbits can reduce the early postoperative effects on spermatogenesis.

METHODSTwenty-nine normal male Japanese white rabbits (aged 4-6 months) were subjected to unilateral close-ended (conventional) or open-ended (the cut end of the juxta-epididymal vas deferens not ligated) vasectomy via the inguinal canal. Ten days and 3 months after operation, testes, epididymides and vasa deferentia were removed and methacrylate resin-embedded sections prepared. The histology of the testis, epididymis and vas deferens was examined under light microscope, and the volume and diameter of the seminiferous tubules were quantitatively studied using stereological methods.

RESULTSNeither of the methods of vasectomy led to apparent damage to spermatogenesis on the vasectomized side in comparison with the contralateral sham-operated side, but the juxta-epididymal vas deferens on the vasectomized side was highly distended and contained numerous sperm 3 months after operation.

CONCLUSIONVasectomy away from the cauda epididymis has no significant early postoperative effects on spermatogenesis in rabbits.

The first Viet Nam baby born from intracytoplasmic sperm injection using testicular sperm from impaired spermatogenesis testes in 1/3/2004. There was approximately 50000 sperm after preparation, among them 20% was motile. From 12 retrieved oocytes, 11 were mature and therefore injected. Five oocytes fertilized and developed into 4 embryos. Embryo transfer was carried out for all 4 embryos. One embryo implanted and kept growing till the 37th week of pregnancy. Patient underwent ceasarian section
Spermatogenesis ; Sperm Retrieval ; Sperm Injections, Intracytoplasmic

Although it is generally accepted that varicocele is a major cause of male infertility, the mechanism by which varicocele exerts its deleterious effect on spermatogenesis still remains obscure. So, to elucidate the cause of infertility that is the result of varicocele, cortisol levels in the internal spermatic vein blood samples were compared with those of the peripheral vein blood samples from 20 patients with varicocele. In 14 of the 20 patients, cortisol levels were found to be lower in the internal spermatic vein blood than in the peripheral vein blood. In the other 6 patients, cortisol levels were higher in the internal spermatic vein blood. However, no significant differences were observed between the concentrations in the internal spermatic vein (13.12+/-12.12 microgram/dl) and those in the peripheral vein (13.89+/-9.94 microgram/dl) of all cases. Therefore it seems unlikely that testicular dysfunction in patients with varicocele is caused by reflux of adrenal venous blood with toxic metabolites into the internal spermatic vein.
Humans ; Hydrocortisone* ; Infertility ; Infertility, Male ; Male ; Spermatogenesis ; Varicocele* ; Veins*

Although it is generally accepted that varicocele is a major cause of male infertility, the mechanism by which varicocele exerts its deleterious effect on spermatogenesis still remains obscure. So, to elucidate the cause of infertility that is the result of varicocele, cortisol levels in the internal spermatic vein blood samples were compared with those of the peripheral vein blood samples from 20 patients with varicocele. In 14 of the 20 patients, cortisol levels were found to be lower in the internal spermatic vein blood than in the peripheral vein blood. In the other 6 patients, cortisol levels were higher in the internal spermatic vein blood. However, no significant differences were observed between the concentrations in the internal spermatic vein (13.12+/-12.12 microgram/dl) and those in the peripheral vein (13.89+/-9.94 microgram/dl) of all cases. Therefore it seems unlikely that testicular dysfunction in patients with varicocele is caused by reflux of adrenal venous blood with toxic metabolites into the internal spermatic vein.
Humans ; Hydrocortisone* ; Infertility ; Infertility, Male ; Male ; Spermatogenesis ; Varicocele* ; Veins*

No abstract available.
Adolescent ; Gonadotropins* ; Humans ; Male ; Olfaction Disorders* ; Puberty* ; Spermatogenesis*