1.Benefit of use of computer network in hospital
Journal of Practical Medicine 1998;344(1):12-14
In the computer network, any one computer can access the database or external equipment (such as printer) in other computer if it is authorized the right of access. Therefore, the manager of scientific research and managers of hospital can collect timely and correctly the information from which can make the correct evaluations and decisions
Neural Networks (Computer)
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hospitals
2.Banded chromosome images recognition based on dense convolutional network with segmental recalibration.
Jianming LI ; Bin CHEN ; Xiaofei SUN ; Tao FENG ; Yuefei ZHANG
Journal of Biomedical Engineering 2021;38(1):122-130
Human chromosomes karyotyping is an important means to diagnose genetic diseases. Chromosome image type recognition is a key step in the karyotyping process. Accurate and efficient identification is of great significance for automatic chromosome karyotyping. In this paper, we propose a model named segmentally recalibrated dense convolutional network (SR-DenseNet). In each stage of the model, the dense connected network layers is used to extract the features of different abstract levels of chromosomes automatically, and then the concatenation of all the layers which extract different local features is recalibrated with squeeze-and-excitation (SE) block. SE blocks explicitly construct learnable structures for importance of the features. Then a model fusion method is proposed and an expert group of chromosome recognition models is constructed. On the public available Copenhagen chromosome recognition dataset (G-bands) the proposed model achieves error rate of only 1.60%, and with model fusion the error further drops to 0.99%. On the Padova chromosome dataset (Q-bands) the model gets the corresponding error rate of 6.67%, and with model fusion the error further drops to 5.98%. The experimental results show that the method proposed in this paper is effective and has the potential to realize the automation of chromosome type recognition.
Chromosomes
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Humans
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Neural Networks, Computer
3.Initiation of the computer network in the health sector
Journal of Medical and Pharmaceutical Information 1999;(1):5-9
Vietnam officially integrated into the Internet in 19th November 1997. The health sector actively prepared for connecting the Internet via National gate, currently set up the local area network (LAN) to establish the Intranet of the sector. The Internet the central institute for medical science information would be major institute for setting up this tool.
Neural Networks (Computer)
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Health Care Sector
4.The blind source separation method based on self-organizing map neural network and convolution kernel compensation for multi-channel sEMG signals.
Yong NING ; Shan'an ZHU ; Yuming ZHAO
Journal of Biomedical Engineering 2015;32(1):1-7
A new method based on convolution kernel compensation (CKC) for decomposing multi-channel surface electromyogram (sEMG) signals is proposed in this paper. Unsupervised learning and clustering function of self-organizing map (SOM) neural network are employed in this method. An initial innervations pulse train (IPT) is firstly estimated, some time instants corresponding to the highest peaks from the initial IPT are clustered by SOM neural network. Then the final IPT can be obtained from the observations corresponding to these time instants. In this paper, the proposed method was tested on the simulated signal, the influence of signal to noise ratio (SNR), the number of groups clustered by SOM and the number of highest peaks selected from the initial pulse train on the number of reconstructed sources and the pulse accuracy were studied, and the results show that the proposed approach is effective in decomposing multi-channel sEMG signals.
Algorithms
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Cluster Analysis
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Electromyography
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Neural Networks (Computer)
5.Working Temperature Predication of Artificial Heart Based on Neural Network.
Qilei LI ; Ming YANG ; Wenchu OU ; Fan MENG ; Zihao XU ; Liang XU
Chinese Journal of Medical Instrumentation 2015;39(2):87-112
The purpose of this paper is to achieve a measurement of temperature prediction for artificial heart without sensor, for which the research briefly describes the application of back propagation neural network as well as the optimized, by genetic algorithm, BP network. Owing to the limit of environment after the artificial heart implanted, detectable parameters out of body are taken advantage of to predict the working temperature of the pump. Lastly, contrast is made to demonstrate the prediction result between BP neural network and genetically optimized BP network, by which indicates that the probability is 1.84% with the margin of error more than 1%.
Heart, Artificial
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Neural Networks (Computer)
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Temperature
6.Prediction of drug bioavailability by genetic algorithm and artificial neural network.
Ze WANG ; Xin-Cheng LI ; Wei-Xin ZHU
Acta Pharmaceutica Sinica 2006;41(12):1180-1183
AIMTo set up an artificial neural network system and optimize by genetic algorithm (GA) to predict drug bioavailability.
METHODSGenetic algorithm was used to optimize weights of the artificial neural network. The optimal solution of the artificial neural network model at a specific condition was obtained using the good search ability of genetic algorithm in order to predict drug bioavailability. Volume, refractivity, lgP(c), hydration, polarizability, E(HOMO) and E(LUMO) are inputs of the drug bioavailability prediction neural network, and its output is average drug bioavailability.
RESULTSThe prediction precision of average drug bioavailability of the GA- neural network model is 95.9%.
CONCLUSIONThis model can be used in the forecasting of drug bioavailability.
Algorithms ; Biological Availability ; Neural Networks (Computer)
7.Research on Early Identification of Bipolar Disorder Based on Multi-layer Perceptron Neural Network.
Haowei ZHANG ; Yanni GAO ; Chengmei YUAN ; Ying LIU ; Yuqing DING
Journal of Biomedical Engineering 2015;32(3):537-541
Multi-layer perceptron (MLP) neural network belongs to multi-layer feedforward neural network, and has the ability and characteristics of high intelligence. It can realize the complex nonlinear mapping by its own learning through the network. Bipolar disorder is a serious mental illness with high recurrence rate, high self-harm rate and high suicide rate. Most of the onset of the bipolar disorder starts with depressive episode, which can be easily misdiagnosed as unipolar depression and lead to a delayed treatment so as to influence the prognosis. The early identifica- tion of bipolar disorder is of great importance for patients with bipolar disorder. Due to the fact that the process of early identification of bipolar disorder is nonlinear, we in this paper discuss the MLP neural network application in early identification of bipolar disorder. This study covered 250 cases, including 143 cases with recurrent depression and 107 cases with bipolar disorder, and clinical features were statistically analyzed between the two groups. A total of 42 variables with significant differences were screened as the input variables of the neural network. Part of the samples were randomly selected as the learning sample, and the other as the test sample. By choosing different neu- ral network structures, all results of the identification of bipolar disorder were relatively good, which showed that MLP neural network could be used in the early identification of bipolar disorder.
Bipolar Disorder
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diagnosis
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Humans
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Neural Networks (Computer)
8.Study on the inverse problem of diffuse optical tomography based on improved stacked auto-encoder.
Wenxu TIAN ; Dan YANG ; Zhulin WEI ; Jiao WANG
Journal of Biomedical Engineering 2021;38(4):774-782
The inverse problem of diffuse optical tomography (DOT) is ill-posed. Traditional method cannot achieve high imaging accuracy and the calculation process is time-consuming, which restricts the clinical application of DOT. Therefore, a method based on stacked auto-encoder (SAE) was proposed and used for the DOT inverse problem. Firstly, a traditional SAE method is used to solved the inverse problem. Then, the output structure of SAE neural network is improved to a single output SAE, which reduce the burden on the neural network. Finally, the improved SAE method is used to compare with traditional SAE method and traditional levenberg-marquardt (LM) iterative method. The result shows that the average time to solve the inverse problem of the method proposed in this paper is only 1.67% of the LM method. The mean square error (MSE) value is 46.21% lower than the traditional iterative method, 61.53% lower than the traditional SAE method, and the image correlation coefficient(ICC) value is 4.03% higher than the traditional iterative method, 18.7% higher than the traditional SAE method and has good noise immunity under 3% noise conditions. The research results in this article prove that the improved SAE method has higher image quality and noise resistance than the traditional SAE method, and at the same time has a faster calculation speed than the traditional iterative method, which is conducive to the application of neural networks in DOT inverse problem calculation.
Algorithms
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Neural Networks, Computer
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Tomography, Optical
9.Labelling, segmentation and application of neural network based on machine learning of three-dimensional intraoral anatomical features.
Cheng LI ; Hu CHEN ; Yong WANG ; Yu Chun SUN
Chinese Journal of Stomatology 2022;57(5):540-546
With the advent of the era of big data, artificial intelligence based on machine learning, especially artificial neural network has rapidly developed and applicated in the field of stomatology, owning huge potential in segmentation and labelling of three-dimensional intraoral anatomical features. Automatic segmentation, labelling and diagnosis can assist dentists and technicians to complete heavy and repeat work, change stomatology from subjective perception to objective science, and help to make diagnosis and treatment plan efficiently and accurately. This review briefly summarized related knowledge and development of machine learning and artificial neural network, its application status and existing problems in the field of segmentation and labelling of three-dimensional intraoral anatomical features, and provided an outlook of its future development.
Artificial Intelligence
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Machine Learning
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Neural Networks, Computer
10.Study on noninvasive blood glucose detection method using the near-infrared light based on particle swarm optimization and back propagation neural network.
Donghai YE ; Jinxiu CHENG ; Zhong JI
Journal of Biomedical Engineering 2022;39(1):158-165
Most of the existing near-infrared noninvasive blood glucose detection models focus on the relationship between near-infrared absorbance and blood glucose concentration, but do not consider the impact of human physiological state on blood glucose concentration. In order to improve the performance of prediction model, particle swarm optimization (PSO) algorithm was used to train the structure paramters of back propagation (BP) neural network. Moreover, systolic blood pressure, pulse rate, body temperature and 1 550 nm absorbance were introduced as input variables of blood glucose concentration prediction model, and BP neural network was used as prediction model. In order to solve the problem that traditional BP neural network is easy to fall into local optimization, a hybrid model based on PSO-BP was introduced in this paper. The results showed that the prediction effect of PSO-BP model was better than that of traditional BP neural network. The prediction root mean square error and correlation coefficient of ten-fold cross-validation were 0.95 mmol/L and 0.74, respectively. The Clarke error grid analysis results showed that the proportion of model prediction results falling into region A was 84.39%, and the proportion falling into region B was 15.61%, which met the clinical requirements. The model can quickly measure the blood glucose concentration of the subject, and has relatively high accuracy.
Algorithms
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Blood Glucose
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Humans
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Neural Networks, Computer