1.Mycobacterium chelonae Skin Infection after Autologous Fat Transplantation.
Joon Bum LEE ; Jin Woong JUNG ; Young Wook RYOO ; Sung Ae KIM
Korean Journal of Dermatology 2017;55(10):710-711
No abstract available.
Mycobacterium chelonae*
;
Mycobacterium*
;
Skin*
2.A Case of Cutaneous Mycobacterium chelonae Infection Induced by Body Scurbbing
Jee Yon SHIN ; Dae Hwi EUN ; Ji Yeoun LEE ; Tae Young YOON
Annals of Dermatology 2019;31(6):683-685
No abstract available.
Mycobacterium chelonae
;
Mycobacterium
3.Disseminated Mycobacterium chelonae Infection in an Immunosuppressed Patient.
Jung Eun SEOL ; In Ho PARK ; Jeong Nan KANG ; Hyojin KIM ; Ho Suk SUNG
Korean Journal of Dermatology 2014;52(8):584-585
No abstract available.
Humans
;
Immunosuppression
;
Mycobacterium chelonae*
4.A Case of Mycobacterium chelonae Infection at the Site of Acupuncture.
Byeol HAN ; Min Wha CHOI ; Tae Young HAN ; June Hyunkyung LEE ; Sook Ja SON
Korean Journal of Dermatology 2017;55(10):717-720
No abstract available.
Acupuncture*
;
Mycobacterium chelonae*
;
Mycobacterium*
;
Nontuberculous Mycobacteria
5.TWo Cases of Mycobacterium Chelonae Keratitis at the Interface after Laser in Situ Keratomileusis.
Byung Sung JUN ; Roo Min JUN ; Eung Kweon KIM
Journal of the Korean Ophthalmological Society 2003;44(3):760-766
PURPOSE: To describe two cases of bacterial keratitis with Mycobacterium chelonae after laser in situ keratomileusis (LASIK) METHODS: Two cases of non-tuberculous mycobacterial keratitis occurred in the interface between flap and stromal bed 8 and 15 days after LASIK. In both cases, we documented acid fast bacilli in intraoperative staining of the interfacial lesion and confirmed them with microbial culture. Appropriate medical therapies were followed. RESULTS: Mycobacterium chelonae were incubated in both cases. In the first case, stromal infiltration improved after 2 months of medical therapy, but in the course of tapering antibiotics, infiltration was reaggravated. Removal of the flap resulted in the improvement. In the second case which were developed in both eyes, stromal infiltration was much severe and poorly responded to medical therapy with more frequent initial postoperative steroid use. CONCLUSIONS: Mycobacterium chelonae should be considered as one of the causes of keratitis after LASIK and topical steroid may aggravate clinical course. Long-term medical treatment with oral and topical antibiotics for more than 2 months, and even excision of the flap may be required to control the infection.
Anti-Bacterial Agents
;
Keratitis*
;
Keratomileusis, Laser In Situ*
;
Mycobacterium chelonae*
;
Mycobacterium*
6.Comparison of Mycobactericidal Activity of 12 Kinds of Disinfectants for Mycobacterium chelonae.
Jin Mee HWANG ; Yeon Joon PARK ; So Yeon KIM ; Moon Won KANG ; Byung Kee KIM
Korean Journal of Nosocomial Infection Control 2000;5(1):1-8
BACKGROUND: Cleaning and disinfection of fiberoptic bronchoscope requires careful attention, especially to mycobacterium species because the contamination of mycobacteria could raise confusion on diagnosis. Recently, we detected contamination of Wydex(R) solution used in bronchoscope washer with Mycobacterium chelonae. In this study, we evaluated the mycobactericidal effect of 12 kinds of disinfectants for M. chelonae. METHOD: To evaluate the bactericidal effect of Wydex(R) 2%, Cidex(R) 2.25%, Cidex(R) 3%, Bacteriokiller (BK) disinfectant, Perasafe(R), HICLO-S(R), Lamicine(R), ethanol, Instrusept(R), Virkon(R), Betadine(R), and Vipon(R) against M. chelonae, culture was performed after exposure of two M. chelonae strains (ATCC 35749, the type strain and the strain isolated from contaminated Wydex(R) solution) to each disinfectant solution. The growth of organism was examined for up to 8 weeks. RESULTS: Growth of M. chelonae (reference strain of ATCC 35749 and isolated strain) was observed after a week incubation for Wydex(R) 2%, Cidex(R) (2.25%, 3%) and control. For BK disinfectant and Perasafe(R), they grew after 2-3 weeks, and 3-4 weeks, respectively. For HICLO-S(R) and Lamicine(R), only the contaminated strain grew after two and three weeks, respectively. For ethanol, Virkon(R), Betadine(R), Vipon(R), and Instrusept(R) , growth was not observed from either strain. CONCLUSIONS: On the basis of these results, Instrusept(R), virkon(R), ethanol, Betadine(R), and Vipon(R) were effective for the disinfection of M. chelonae. Especially, Instrusept(R) was thought to be useful as a disinfectant for bronchoscopes because it has advantages including non-corrosiveness, chemical stability, and non-irritativeness. And additional washing with ethanol might be effective. The finding that strain isolated from contaminated bronchoscopes was more resistant to disinfectants than reference strain suggested that the more resistant strains are selected throughout the improper disinfection.
Bronchoscopes
;
Diagnosis
;
Disinfectants*
;
Disinfection
;
Ethanol
;
Mycobacterium chelonae*
;
Mycobacterium*
7.Soft Tissue Infection Caused by Rapid Growing Mycobacterium following Medical Procedures: Two Case Reports and Literature Review.
Shih Sen LIN ; Chin Cheng LEE ; Tsrang Neng JANG
Annals of Dermatology 2014;26(2):236-240
Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or the multimedia. Most of them occurred after a plastic surgery, and medical or non-medical procedures. Here, we reported two cases of these infections following medical procedures. We also discussed common features and the clinical course of the disease, the characteristics of the infected site, and the treatment strategy. The literatures were also reviewed, and the necessity of the treatment guidelines was discussed.
Multimedia
;
Mycobacterium chelonae
;
Mycobacterium Infections
;
Mycobacterium*
;
Periodicals
;
Periodicals as Topic
;
Soft Tissue Infections*
;
Surgery, Plastic
;
Taiwan
8.A Case of Cutaneous Infection with Mycobacterium Chelonae.
Hee Jin HAN ; Kweon Soo KANG ; Bo Hyun LEE ; Chun Wook PARK ; Cheol Heon LEE ; Chong Woo YOO
Korean Journal of Dermatology 2004;42(3):320-323
Mycobacterium chelonae is a rapidly growing atypical mycobacteria that can cause both systemic and cutaneous infections as a human pathogen. This saprophyte is ubiquitous in the environment and has been found in water, soil, and dust particles. Clarithromycin is a highly specific drug against M. chelonae. A 53-year-old man had a nodule on the dorsum of his right hand that had developed in 3~4 months. The lesion was a slightly tender 2.0x1.5cm erythematous nodule and had an overlying ruptured pustule. Culture demonstrated atypical mycobacterim, with a polymerase chain reaction (PCR) which confirmed M. chelonae.
Clarithromycin
;
Dust
;
Hand
;
Humans
;
Middle Aged
;
Mycobacterium chelonae*
;
Mycobacterium*
;
Nontuberculous Mycobacteria
;
Polymerase Chain Reaction
;
Soil
9.Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium chelonae: A Case Report.
Yousang KO ; Wooyoul KIM ; Beom Su SHIN ; Hongseok YOO ; Jung Seop EOM ; Ji Hyun LEE ; Byung Woo JHUN ; Su Young KIM ; Go Eun CHOI ; Sung Jae SHIN ; Won Jung KOH
Tuberculosis and Respiratory Diseases 2013;74(4):191-194
Mycobacterium chelonae lung disease is very rare. We report a case of lung disease caused by M. chelonae in a previously healthy woman. A 69-year-old woman was referred to our hospital because of hemoptysis. A computed tomography (CT) scan of the chest revealed bronchiolitis associated with bronchiectasis in the lingular division of the left upper lobe. Nontuberculous mycobacteria were isolated three times from sputum specimens. All isolates were identified as M. chelonae by various molecular methods that characterized rpoB and hsp65 gene sequences. Although some new lesions including bronchiolitis in the superior segment of the left lower lobe developed on the chest CT scan 35 months after diagnosis, she has been followed up without antibiotic therapy because of her mild symptoms. To the best of our knowledge, this is the first case of M. chelonae lung disease in Korea in which the etiologic organisms were confirmed using molecular techniques.
Bronchiectasis
;
Bronchiolitis
;
Female
;
Hemoptysis
;
Humans
;
Korea
;
Lung
;
Lung Diseases
;
Mycobacterium
;
Mycobacterium chelonae
;
Nontuberculous Mycobacteria
;
Sputum
;
Thorax
10.Studies on Identification and Drug Resistance of Atypical Mycobacteria Isolated from Patients with Pulmonary Tuberculosis.
Dong Hyun CHUNG ; Sung Kwang KIM ; Joo Deuk KIM
Yeungnam University Journal of Medicine 1984;1(1):49-58
The differential diagnosis of atypical mycobacteriosis caused by atypical mycobacteria (with the exception of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium leprae) which are widly distributed in soil and water, from pulmonary tuberculosis is possible only when atypical mycobacteria are isolated and identified. In this investigation, attempts were made to isolate atypical mycobacteria from persons registered as tuberculosis patients in the Anyang Health Center in Anyang City, Kyungki province, Korea. Biological and biochemical tests were performed for the atypical mycobacteria isolated from these patients, also retrospective analysis of clinical and X-ray findings of the patients with bacteriologically confirmed atypical mycobacteriosis were done. The results can be summarized as follows; 1. 103 strains of mycobacteria were isolated among 334 sputum samples from patients. 2. Among the isolated mycobacteria, 10 strains (9.7%) were found to be an atypical mycobacteria and 93 strains (90.3%) were tubercle bacilli of human type. 3. On the basis of Runyon's grouping of atypical mycobacteria, there were 3 strains (30.0%) of scotochromogen and nonphotochromogen respectively, 4 strains (40.0%) of rapid grower, and no photochromogen. 4. By biochemical tests, 3 strains of scotochromogen were identified as Mycobacterium scroful-aceum (2 strains) and Mycobacterium szulgai (1 strain) 3 strains of nonphotochromogen were Mycobacterium avium-complex (2 strains) and Mycobacterium terriae (1 strain), and 4 strains of rapid grower were Mycobacterium fortuitum (3 strains) and Mycobacterium chelonae. 5. In drug sensitivity tests, all 10 strains isolated atypical mycobacteria showed resistance to various concentration of INH and SM and low concentration (10 mcg, 40 mcg and 50 mcg) of EB, TH, and CS, and were sensitive to only high concentration (20 mcg and 100 mcg) of EB, TH, CS, and RFP. 6. In analysis of clinical findings by the patients with bacteriologically confirmed atypical mycobacteriosis, it was found that clinical symptoms of these patients appeared not to be mild than those of patients with pulmonary tuberculosis. The patients with atypical mycobacteriosis had been treated for pulmonary tuberculosis for a long time and they showed no improvement.
Diagnosis, Differential
;
Drug Resistance*
;
Gyeonggi-do
;
Humans
;
Korea
;
Mycobacterium
;
Mycobacterium bovis
;
Mycobacterium chelonae
;
Mycobacterium fortuitum
;
Mycobacterium tuberculosis
;
Nontuberculous Mycobacteria*
;
Retrospective Studies
;
Soil
;
Sputum
;
Tuberculosis
;
Tuberculosis, Pulmonary*
;
Water