Aged ; Humans ; Liver Neoplasms ; diagnosis ; pathology ; Male ; Neurilemmoma ; diagnosis ; pathology ; Retroperitoneal Neoplasms ; diagnosis ; pathology

Angiomyolipoma/diagnosis ; Angiomyolipoma/*pathology ; Biopsy, Needle ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/*pathology ; Diagnosis, Differential ; Liver Neoplasms/diagnosis ; Liver Neoplasms/*pathology

Carcinoma, Hepatocellular ; pathology ; Diagnosis, Differential ; Humans ; Liver Cirrhosis ; pathology ; Liver Neoplasms ; pathology ; Precancerous Conditions ; pathology

A previously healthy 22-year-old woman was admitted with a complaint of right upper quadrant abdominal pain for 2 weeks. Her past history was not remarkable. On admission, HBsAg and anti-HCV were negative and alpha-FP was within normal range. Abdominal sonography and CT showed a mass in liver measuring 10 11 cm with features of central necrosis and hemorrhage. On 6th hospital day, hemoperitoneum developed suddenly. She underwent emergency laparotomy and trisegmentectomy. Intraoperative finding revealed a hemoperitoneum with a tumor filled with liquefied necrotic tissues. Microscopically, the tumor was mostly composed of pleomorphic spindle cells with abundant anastomosing vascular channels and partly composed of tumor cells with trabecular arrangement. On immunohistochemical staining, tumor cells reacted with cytokeratin and vimentin, while CD34 and hepatocyte staining revealed negative. She died 2 months after the operation. We report a case of rapidly deteriorated primary sarcomatoid hepatocellular carcinoma in a young female without any risk factor.
Adult ; Carcinoma, Hepatocellular/diagnosis/*pathology ; Female ; Humans ; Liver Neoplasms/diagnosis/*pathology ; Sarcoma/diagnosis/*pathology

Small cell neuroendocrine carcinoma is a type of undifferentiated, malignant neuroendocrine tumor. Most of neuroendocrine tumors exhibit well-differentiated features and are classified as carcinoid tumors. However, carcinomas of the liver with anaplastic characters, which are classified as small-cell carcinomas are extremely rare and only few cases have been reported in the literature. We report an unusual case of primary small cell neuroendocrine carcinoma of the liver in a 67-year-old man. The patient was found to have a palpable mass on right upper quadrant of abdomen on physical examination. The diagnosis was made by immunohistochemical stains of biopsied specimen from the liver. Other possible primary site was excluded by radiologic and endoscopic evaluations. The tumor was composed of small monotonous and hyperchromatic poorly differentiated cells with higher nuclear to cytoplasmic ratio, and were positive for neuroendocrine tissue markers such as synaptophysin, c-kit, and CD56.
Aged ; Carcinoma, Neuroendocrine/*diagnosis/pathology ; Carcinoma, Small Cell/*diagnosis/pathology ; Humans ; Liver Neoplasms/*diagnosis/pathology ; Male

No abstract available.
Carcinoma, Hepatocellular/*diagnosis/pathology ; Hepatitis B/complications/*diagnosis ; Humans ; Liver Cirrhosis/complications/*pathology ; Liver Neoplasms/*diagnosis/pathology ; Male ; Middle Aged

Aged ; Colonic Neoplasms ; complications ; diagnosis ; Diaphragm ; pathology ; Humans ; Liver Neoplasms ; pathology ; Male ; Neoplasm Metastasis ; pathology

No abstract available.
Adult ; Diagnosis, Differential ; Hemangioendothelioma, Epithelioid/diagnosis/*pathology ; Humans ; Liver Neoplasms/diagnosis/*pathology ; Male ; Tumor Markers, Biological

Carcinoma, Hepatocellular ; diagnosis ; pathology ; Diagnosis, Differential ; Humans ; Liver Neoplasms ; diagnosis ; pathology

No abstract available.
Bile Duct Neoplasms/*diagnosis/pathology ; *Bile Ducts, Intrahepatic ; Carcinoma, Hepatocellular/*diagnosis/pathology ; Cholangiocarcinoma/*diagnosis/pathology ; Humans ; Liver Neoplasms/*diagnosis/pathology ; Male ; Middle Aged ; Mixed Tumor, Malignant/*diagnosis/pathology