1.Association of maternal clinical factors with neonatal respiratory morbidity in meconium‑stained labor among term parturients: A retrospective cohort study
Jelli‑Ann Arcibal Magno ; Brenda Bernadette B. Zamora
Philippine Journal of Obstetrics and Gynecology 2023;47(4):165-177
Objective:
This study aimed to determine the maternal clinical factors associated with neonatal respiratory morbidity and other adverse neonatal outcomes in meconium-stained labor among term parturients.
Methodology:
A retrospective cohort study was done on admitted obstetric patients with term gestation and had meconium-stained labor. Maternal clinical factors such as age, parity, gestational age, manner of delivery, duration of labor, presence of term prelabor rupture of membranes (PROM), character of meconium-stained liquor (MSL), and presence of comorbidities were identified and analyzed to determine their association with neonatal respiratory morbidity and other adverse neonatal outcomes.
Results:
In this study, there were 986 cases identified to have meconium-stained labor, and 168 developed neonatal respiratory morbidity. As to primary outcome, maternal clinical factors, such as age >35 years, multiparity, age of gestation >41 weeks, prolonged labor, presence of PROM, significant MSL upon admission, presence of change from nonsignificant to significant MSL, presence of intrauterine growth restriction, and hypertension, were all shown to be statistically significant.
Conclusion
The presence of maternal clinical factors in meconium-stained labor was observed to be a risk factor in developing neonatal respiratory morbidity and other adverse neonatal outcomes. Hence, identification of maternal risk factors and early detection of meconium-stained amniotic fluid are vital in administering timely intervention to labor and delivery to reduce neonatal complications.
Infant, Newborn, Diseases
3.Heart diseases and pregnancy at Institue for Protection of Mothers and Newborns
Journal of Medical and Pharmaceutical Information 2004;0(7):35-39
During 1 year (2001), there were 86 cardiac patients (1.18% of all pregnancy) treated at IPMN. Acquired heart diseases rate is 81.79%, of which the most frequent ones are mitral stenosis and regurgitation (37.02%), followed by pure mitral stenosis (12.79%). Congenital cardiopathy accounted for 18.58%. The most frequent complications are heart failure (91.67%). The mortality is 0%. The main treatment is Cesar operation (55.81%); forceps (32.56%)
Heart Diseases
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Pregnancy
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Infant, Newborn
4.Radiologic Features of a Tailgut Cyst in a Neonate: A Case Report.
Journal of the Korean Radiological Society 2008;58(2):177-180
A tailgut cyst is a rare congenital abnormality located in the retrorectal space and is usually manifested during childhood or adulthood. We report the MR, CT and ultrasound findings of a tailgut cyst in a 23-day-old neonate.
Congenital Abnormalities
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Humans
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Infant, Newborn
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Infant, Newborn, Diseases
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Sacrococcygeal Region
5.Expert consensus on clinical management of neonatal seizures.
Chinese Journal of Pediatrics 2022;60(11):1127-1133
8.Clinical guidelines for the diagnosis and treatment of neonatal necrotizing enterocolitis (2020).
Chinese Journal of Contemporary Pediatrics 2021;23(1):1-11
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease of neonates, especially of preterm infants, with high morbidity and mortality. The surviving infants may have digestive tract and neurological sequelae. Therefore, the prevention and treatment of NEC are of great significance in improving survival rate and survival quality of neonates. To provide evidence-based recommendations for management of NEC, the guidelines were developed based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) and the current domestic and overseas studies.
Enterocolitis, Necrotizing/therapy*
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Humans
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Infant
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Infant, Newborn
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Infant, Newborn, Diseases
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Infant, Premature
9.Increased CD5 + B Cells in Neonatal Infections.
Korean Journal of Immunology 1997;19(3):399-406
PURPOSE: CD5+ B (B1) cell is a subpopulation of B cells and CD5+ B cells constitute a large fraction of B cells in neonates. CD5 B cells are closely related with autoimmune diseases but the roles and functions in neonates are still unknown. The quantitative changes of CD5+ B cells in neonatal infections were examined to investigate the involvement of CDS+ B cells in neonatal immune reaction to general immunologic stimuli such as infections. Methods: Ten normal neonates and eight neonates with acute febrile diseases were studied. Venous blood was drawn and mononuclear cells were separated by Ficoll-Hypaque. Half was double-stained with FITC-conjugated anti-CD5 and PE-conjugated anti-CD19, and another half with FITC-conjugated anti-CD4 and PE-conjugated anti-CD8. Stained samples were analyzed using fluorescent-activated cell sortor. ...continue...
Autoimmune Diseases
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B-Lymphocytes*
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Humans
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Infant, Newborn
10.Use of selected thermolysis effect of Copper Vapor Lasers to treat plane hemagioma and cutaneous pigmented stain
Journal of Practical Medicine 2001;399(7):2-6
The condition in which melanin level was higher than normal level in a certain skin area was called as skin pigmented lesion. Hemagioma is a vascular lesion of skin that found commonly in the newborns. 578nm-wave Copper Vapor Laser that produces extremely short pulse of 20nm/s is used to treat plane hemagioma. Copper Vapor Laser also produces 511nm waves that was absorbed strongly by melanin, so it is also used to treat pigmented lesions of skin. Pulsed laser produces significant higher effect than wave-continuous laser. The treatment process required 6-8 courses with the intervals of 2-4 months.
Skin Diseases, Vascular
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Infant, Newborn
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therapeutics