1.Fine Needle Aspiration Cytology of Pulmonary Hamartoma: 3 cases.
Na Hye MYONG ; Kyung Ja CHO ; Ja June JANG
Korean Journal of Pathology 1989;23(3):355-358
Fine needle aspiration cytology of three cases of pulmonary hamartoma is presented. Case 1 was in a 67-year-old man with a 7 cm-sized left lung mass. Case 2 and 3 were in 47 and 53 year old females and consisted of 3 cm and 2 cm-sized right lung nodules, respectively. Fine needle aspiration of the masses revealed several fragments of irregularly shaped mature hyaline cartilage or fibromyxoid mesenchyme and sheets of benign epithelial cells in scanty to acellular background. Also scattered were inflammatory cells including lymphocytes, neutrophils and histiocytes and mature fat cells. These features were diagnostic for pulmonary hamartoma and case 1 was histologically confirmed by following surgical excision of the mass. Differential diagnoses about pulmonary hamartoma in the respect of conditions capable of producing cartilage on fine needle aspiration, were discussed.
Female
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Male
;
Humans
;
Diagnosis, Differential
;
Hamartoma
2.Mesenchymal Hamartoma of the Liver in Adults.
Min Hyung KIM ; Moon Seok CHOI ; Jun Hyeok LEE ; Kwang Cheol KOH ; Seung Woon PAIK ; Byung Chul YOO ; Jae Hong JUNG ; Sung Chul CHOI ; Dong Hee KIM ; Hyuk LEE ; Bong Geun SONG ; Jong Chul RHEE ; Chul Geun PARK
The Korean Journal of Hepatology 2003;9(1):31-34
Mesenchymal hamartoma of the liver (MHL) is a rare benign tumor usually found in childhood, especially during the first two years. MHL is extremely rare in adults. Most reported cases present with a slow growing abdominal mass. It is thought to be a developmental anomaly and consists of bile ducts, hepatocytes and mesenchymal tissue. We report a case of mesenchymal hamartoma of the liver in an adult male with a brief review of the literature.
Adult
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*Hamartoma/diagnosis/pathology
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Humans
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*Liver Diseases/diagnosis/pathology
;
Male
3.Hamartoma of the Spleen.
Woo Jung KWEON ; Jin Sun BAE ; In Sang SONG
Journal of the Korean Surgical Society 2000;58(1):144-148
Splenic hamartomas are rare benign tumors, which are usually small in size and asymptomatic and which are discovered incidentally at surgery or autopsy. The authors report on a case of splenic hamar toma in a 35-year-old man with intermittent left upper quardrant pain, who underwent an elective splenc tomy. Final pathology confirmed diagnosis of a hamartoma of the red pulp in the spleen. The patient's symptoms were resolved after the splenectomy. A splenic hamartoma should be kept in mind in the differential diagnosis of splenic tumors. The authors suggest that a splenectomy is indicated in cases where malignancy cannot be excluded and in cases of associated clinical symptoms or hematologic disorders.
Adult
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Autopsy
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Diagnosis
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Diagnosis, Differential
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Hamartoma*
;
Humans
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Pathology
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Spleen*
;
Splenectomy
4.Four Cases Which were Mis-diagnosed as Granuloma Pyogenicum.
Duck Pyo HONG ; Jae Sun KIM ; Jong Min KIM ; Eil Soo LEE
Korean Journal of Dermatology 1985;23(5):701-706
We have experienced 4 cases which were clinically diagncsed as granuloma pyogenicum, but histologically as a malignant melanorna, an eccrine angiomatous hamartoma with granuloma pyogenicum, a subungual exostosis, and a lipoma, with granulation tissue. A granuloma pyogenicum may have clinical resemblances to various benign or malignant lesions. Therefore, any lesion that resembles a granuloma pyogenicum should have this clinical impression confirmed by histologic examination.
Diagnosis, Differential
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Exostoses
;
Granulation Tissue
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Granuloma*
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Granuloma, Pyogenic*
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Hamartoma
;
Lipoma
5.A Case of Brunner's Gland Hamartoma with Severe Anemia and Intussusception.
Jin Hyok HWANG ; Jin KIM ; Sun Hi MOON ; You Sun KIM ; Gwang Hoon WOO ; Jun Oh JUNG ; Yong Tae KIM ; Hyun Chae JUNG ; In Sung SONG ; Kyoo Wan CHOI ; Chung Yong KIM ; Sun Whe KIM
Korean Journal of Gastrointestinal Endoscopy 1997;17(5):691-695
Brunner's gland hamartomas are rare duodenal tumors with characteristic pathologic featmes. The usual clinical presentation is nonspecific symptoms, obstructive symptoms, or intestinal bleeding. The majority of these tumors are less than 3 cm in diameter. In cases of larger size, the manifestations are usually intestinal obstruction or intestinal bleeding. The cases with massive gastrointestinal bleeding and severe anemia, requiring transfusion are rare. The diagnosis is made by radiologic studies and gastroduodenoscopy. The treatment of Brunner's gland hamartomas should be conservative, since they are not premalignant, However, the lesions originate in the submucosa, so the confimative diagnosis usually cannot be made by endoscopie biopey. For definitive diagnosis and relief of symptoms, the lesions must be removed surgically or endoscopically. Endoscopic excision is indicated if the tumar is pedunculated. We recently experienced a case of Brunner's gland hamartoma of about 5.5 cm in diameter with intestinal bleeding, requiring transfusion and intussusception. Preoperative diagnosis was submucosal tumor, such as lymphoma, with duodeno-duodenal intussusception. After surgical removal, the resected specimen showed the histologic features of Bruaner's gland hamartoma.
Anemia*
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Diagnosis
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Duodenum
;
Hamartoma*
;
Hemorrhage
;
Intestinal Obstruction
;
Intussusception*
;
Lymphoma
6.A Case of Intraosseous Hemangioma of the Maxilla Bone.
Joo Hyun JUNG ; Byoung Seo JEONG ; Seon Tae KIM ; Il Gyu KANG
Korean Journal of Otolaryngology - Head and Neck Surgery 2013;56(1):45-47
Intraosseous hemangioma is a rare tumor, occurring especially in the maxilla. Because hemangioma is a benign tumor with increased vascularity, some authors call it hamartoma. This tumor originates and expands into bony structures. We experienced a female patient with intraosseous hemangioma of the right maxilla. The tumor was completely removed through a gingivobuccal incision and the feeding vessel was embolized. We report this case regarding the radiologic work-up, differential diagnosis, pathology and treatment with a brief review of the literature.
Diagnosis, Differential
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Female
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Glycosaminoglycans
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Hamartoma
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Hemangioma
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Humans
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Maxilla
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Vascular Neoplasms
7.A Case of Mixed Epithelial and Mesenchymal Hamartoma of Nasopharynx.
Kyoung Min KIM ; Sam Hyun KWON ; Ho Sung PARK ; Myoung Jae KANG
Korean Journal of Otolaryngology - Head and Neck Surgery 2012;55(3):191-193
Mixed epithelial and mesenchymal hamartoma in the nasopharynx is extremely rare. Hamartomas of the nasal cavity or nasopharynx are classified as epithelial, mesenchymal and mixed epithelial and mesenchymal types. We report an incidentally detected lesion arising in a 42-year-old female patient. The mass was resected endoscopically and was diagnosed as mixed epithelial and mesenchymal hamartoma. We report and discuss the pathological features and differential diagnosis of this rare nasopharyngeal hamartoma.
Adult
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Diagnosis, Differential
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Female
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Hamartoma
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Humans
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Nasal Cavity
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Nasopharynx
8.Nonalcoholic Steatohepatitis.
The Korean Journal of Hepatology 2003;9(2):147-150
No abstract available.
*Bile Duct Diseases/diagnosis
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*Bile Ducts, Intrahepatic
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Female
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*Hamartoma/diagnosis
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Humans
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Liver Diseases/diagnosis
;
Middle Aged
9.Temporal lobe epilepsy with hypothalamic hamartoma: a rare case.
An-Chao YANG ; Kai ZHANG ; Jian-Guo ZHANG ; Huan-Guang LIU ; Ning CHEN ; Ming GE ; Qin BAI ; Fan-Gang MENG
Chinese Medical Journal 2011;124(7):1114-1117
Refractory gelastic seizure is one of the most common clinical manifestations in patients with hypothalamic hamartoma (HH) and HH is usually regarded as the epileptogenic focus. A young female patient with a small HH and refractory seizures is reported here. However, both the seizure semiology and results of electroencephalogram monitoring indicated the right temporal region was the epileptogenic focus. Thus a standard right anterior temporal lobectomy was performed while the hamartoma preserved. There was a marked improvement in both seizure frequency and quality of life during a 13-month follow-up. The outcome supported the concept that independent epileptogenic focus outside of the hypothalamus might occur in patients with HH.
Adult
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Electroencephalography
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Epilepsy, Temporal Lobe
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diagnosis
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surgery
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Female
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Hamartoma
;
diagnosis
;
surgery
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Humans
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Hypothalamic Diseases
;
diagnosis
;
surgery
10.CT Findings of Pulmonary Hamartoma: Analysis of 16 Histopathologically-proven Cases.
Ji Hoon SHIN ; Jin Seong LEE ; Koun Sik SONG ; Tae Hwan LIM
Journal of the Korean Radiological Society 1998;38(2):259-262
PURPOSE: To evaluate the CT findings of histopathologically proven pulmonary hamartoma MATERIALS AND METHODS: CT findings of 16 patients with pulmonary hamartoma, histopatologically proven between 1990 and 1996, wereretrospectively reviewed. Diagnosis was based on thoracotomy9n=11) or fine-needle aspiration biopsy(n=5). Weanalyzed the location, margin discreteness, shape, and size of the mass, and the presence of calcification or fatdensity, as seen on CT scan. RESULTS: All 16 tumors showed a discrete and smooth margin and there was nopredilection for any specific site. They were lobulated(11/16, 69%), round(4/16, 25%) or oval(1/16, 6%) and wereless than 1cm(2/16), 1~ < 2cm(4/16), 2~ < 3cm(5/16), 3~ < 4cm(3/16) or 4~5cm(2/16) in size. Nine of 16 cases(56%)showed calcification;this was either popcorn-type(n=3), stippled(n=3), eccentric(n=2), or diffuse(n=1). Five of 16cases(31%) showed fat attenuation. CONCLUSION: On CT, pulmonary hamartomas showed a discrete margin, werelobulated (rather than round or oval) and varied in size. calcification was more common than fat density. These CTfindings may be useful for the differential diagnosis of pulmonary hamartoma.
Biopsy, Fine-Needle
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Diagnosis
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Diagnosis, Differential
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Hamartoma*
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Humans
;
Tomography, X-Ray Computed