5.Research progress and stress-induced variation of DNA methylation in plants.
Zhen YANG ; Xuanming PENG ; Yiyan ZHANG ; Yuanhai ZHANG ; Yong ZHANG
Chinese Journal of Biotechnology 2016;32(12):1642-1653
Chemical modification of DNA bases in recent years has been one of the hot areas of life science research. DNA methylation is a common epigenetic phenomenon and can change the genetic performance without changing the DNA sequence. Various stress factors can induce the variation of DNA methylation in plants, but the response mechanism is still unknown. In this paper, the progress of DNA methylation in plants was reviewed. In combination with the researchconclusions of our own research group, the DNA methylation variation induced by 7Li ion beam and gamma ray was reported to provide a basis for DNA methylation, which may be involved in the phenotypic plasticity of plants.
DNA Methylation
;
Epigenesis, Genetic
;
Epigenomics
;
Plants
;
genetics
10.Research Progress of m6A-Methylation in Acute Leukemia-Review.
Qiu-Ni CHEN ; Yue CHEN ; Ting-Ting JI ; Liang YU
Journal of Experimental Hematology 2019;27(6):2014-2018
Epigenetic abnormalities play an important role in the pathogenesis of hematological malignancies, especially acute leukemia (AL). Similar to DNA methylation and histone modifications, RNA methylation is another important epigenetic modification. m6A methylation is one of the most prevalent and extensively studied RNA methylation. m6A methylation is involved in many biological and pathological process. Recent studies have found that m6A methylation is involved in the occurrence, development and drug-resistance of AL. This review focuses on the research progress of m6A methylation in AL.
DNA Methylation
;
Epigenesis, Genetic
;
Humans
;
Leukemia
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