1.Research advances in abnormal RNA splicing in neurodegenerative diseases
Journal of Apoplexy and Nervous Diseases 2025;42(8):754-761
RNA splicing is an essential cellular process in which a series of protein-nucleic acid complexes cut and splice the products of gene transcription to generate mature RNA， and it plays an important role in maintaining the normal life activities of cells. Extensive studies have shown that proteins and nucleic acids associated with RNA splicing undergo the pathological changes such as aggregation in neurodegenerative diseases， and inadequate RNA splicing is observed in lesions. Genetic alterations within RNA splicing-related genes can cause neurodegenerative diseases. All these findings suggest that abnormalities in RNA splicing pathways may play a significant role in the pathogenesis of neurodegenerative diseases. This article reviews the research advances in the alterations of RNA splicing in common neurodegenerative diseases in terms of histopathology， biochemistry， and genetics， as well as related cell biology and animal models， in order to clarify their role in the pathogenesis of neurodegenerative diseases.
Alzheimer Disease
;
Parkinson Disease
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Journal of the Korean Neurological Association 1986;4(1):38-42
No abstract available.
Parkinson Disease*
3.The Modern Medical Treatment of Parkinson's Disease.
Journal of the Korean Neurological Association 1986;4(1):28-37
No abstract available.
Parkinson Disease*
4.A Case of Subungual Bowen's Disease.
Heun Joo LEE ; Jung MIN ; Sanghyeon HWANG ; Ho Joo JUNG ; Ji Hye PARK ; Ga Young LEE ; Won Serk KIM
Korean Journal of Dermatology 2014;52(11):830-831
No abstract available.
Bowen's Disease*
5.Hirschsprung's Disease.
Journal of the Korean Association of Pediatric Surgeons 2002;8(1):39-40
No abstract available.
Hirschsprung Disease*
6.Caroli's Disease.
Jong Hoon PARK ; In Hyun CHO ; Sun Ja LEE ; Dong Hyuk KUM ; Soo Dong PAI
Journal of the Korean Pediatric Society 1981;24(4):401-406
No abstract available.
Caroli Disease*
7.A Case of Gaucher's Disease.
Hyo Nam CHO ; Myung Cheol CHO ; Hyung Ro MOON ; Je Geun CHI ; Hyo Min KIM
Journal of the Korean Pediatric Society 1987;30(7):784-790
No abstract available.
Gaucher Disease*
8.Clinical review of Crohn's disease.
Hee Won CHUNG ; Jae Gahb PARK ; Kuhn Uk LEE ; Kuk Jin CHOE ; Jin Pok KIM
Journal of the Korean Society of Coloproctology 1992;8(2):143-150
No abstract available.
Crohn Disease*
9.Analysis of morbidity in operation of Hirschsprung's disease.
Chang Soo KIM ; Kap Tae KIM ; Eul Sam CHUNG
Journal of the Korean Surgical Society 1992;43(2):288-299
No abstract available.
Hirschsprung Disease*
10.The management of Hirschsprung's disease (congenital megacolon).
Journal of the Korean Surgical Society 1992;43(2):244-257
No abstract available.
Hirschsprung Disease*
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