3.Depression and weight loss in low calorie diet and low calorie diet with exercise on obese women.
Jong Muk AHN ; Seong Won KIM ; Jae Hean KANG ; Yun Jun YANG ; Hye Soon PARK ; Hyun Soo KIM
Journal of the Korean Academy of Family Medicine 1999;20(10):1239-1246
BACKGROUND: The relation of initial depression and weight loss in a low calorie diet(LCD) alone or exercise combination in Korean wamen, was considered and change of emotional state after program was determined in this study. METHODS: Sixty obese females were randomly prescribed a LCD(low calorie diet) alone or a LCD with exercise. Thirty obese females were treated with a LCD of 1,000kcal/d for 8weeks(group A). Another thirtyt obese females were treated with a LCD of 1,000kcal/d combined with supervised aerobic exercise for 8 weeks(group B). Questionnaires including Korean-translated Beck Depression Inventory(BDI), Korean- translated Brief Encounter Psychosocial Instrument(BEPSI) were reported before and after 8weeks fo this study. RESULTS: 21 out of 30 obese females in group A and 25 out of 30 obese females in group B completed the study. At the eighth week, mean weight loss was 5.7+/-2.2kg(8.0%) in group A, and 6.8+/-1.7kg(9.5%) in group B. Depression were decreased after program(decreased BDI score in combined group(6.86+/-6.31: p = 0.0001), group A(5.79+/-4.06:p=0.0001) and group B(7.68+/-7.58:p=0.0001), but no statistically significant difference between group A and B was noted(p=0.3309). Initial BDI score was negatively correlated with the percent of weight loss in group A(r =-0.659: p=0.0012). But initial BDI score was not correlated with the percent of weight loss in group B(r =0.099: p=0.637). In group A and B, the percent of weight loss was not correlated with change of BDI score. In group A and B, the change of BDI score was positively correlated with the initial BDI score(group A;r=0.504:p=0.028, group B;r=0.762:p=0.0001). CONCLUSIONS: Regardless of the exercise combination, LCD therapy seemed to decrease diepression. The degree of weight loss was negatively correlated with initial degree of depression. this negative correlation can be compensated by planned thorough exercise.
Caloric Restriction*
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Depression*
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Exercise
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Female
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Humans
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Weight Loss*
;
Surveys and Questionnaires
4.The effects and mechanism of caloric restriction on energy metabolism.
Xiao-Na FAN ; Lin-Xi CHEN ; Ge-Yang XU
Acta Physiologica Sinica 2020;72(3):371-381
Caloric restriction (CR) is explored to limit the caloric intake without malnutrition. CR can affect the levels of various metabolites in organism, such as lipids, free fatty acids, ketones, bile acids and amino acids, etc, and is thought being able to extend the lifespan, postpone and reduce the incidence of age-related disorders (e.g., type 2 diabetes, cancer and cardiovascular diseases). These effects are mainly attributed to the role of CR in energy metabolism. The mechanism of CR on energy metabolism is closely related to biological clock, hormonal production, gastrointestinal flora and inflammation. Here we briefly review the effects and mechanism of CR on energy metabolism.
Caloric Restriction
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Diabetes Mellitus, Type 2
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Energy Metabolism
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Humans
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Longevity
5.The Interplay between Autophagy and Aging.
Jong Ok PYO ; Seung Min YOO ; Yong Keun JUNG
Diabetes & Metabolism Journal 2013;37(5):333-339
Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various factors due to the gradual failure of cellular maintenance. Recent studies have shown that autophagy reduces the stress responses induced by starvation, reactive oxygen species, and the accumulation of intracellular proteins and organelles through cytoprotection, clearance of damaged mitochondria, and lysosomal degradation. Here, we summarize our current understanding of the relationship between autophagy and the aging process.
Aging*
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Autophagy*
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Caloric Restriction
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Cytoprotection
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Mitochondria
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Organelles
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Proteins
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Reactive Oxygen Species
;
Starvation
6.The Interplay between Autophagy and Aging.
Jong Ok PYO ; Seung Min YOO ; Yong Keun JUNG
Diabetes & Metabolism Journal 2013;37(5):333-339
Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various factors due to the gradual failure of cellular maintenance. Recent studies have shown that autophagy reduces the stress responses induced by starvation, reactive oxygen species, and the accumulation of intracellular proteins and organelles through cytoprotection, clearance of damaged mitochondria, and lysosomal degradation. Here, we summarize our current understanding of the relationship between autophagy and the aging process.
Aging*
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Autophagy*
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Caloric Restriction
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Cytoprotection
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Mitochondria
;
Organelles
;
Proteins
;
Reactive Oxygen Species
;
Starvation
7.Calorie Restriction in the Elderly People.
Journal of Korean Medical Science 2013;28(6):797-798
No abstract available.
Aged
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*Caloric Restriction
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Chronic Disease
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Health Promotion
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Humans
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Life Expectancy
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Life Style
;
Malnutrition
8.The Weight Control-Related Attitudes, Dietary Self-Efficacy and Eating Behaviors according to the Perception of Eating Disorder and Obesity Index in Dancing Major High School Girls.
Korean Journal of Community Nutrition 2009;14(4):383-391
This study was performed in order to compare the differences in dietary self-efficacy and eating behaviors as well as the relationship of weight control attitudes according to eating disorder perception and obesity index for high school girls majoring in dance. Almost half (45.5%) of the subjects perceived eating disorders, and the rate of underweight group was 45.7%. Forty-four percent of the group that perceived eating disorders were in modern dance, while 55.0% of the group that did not perceived eating disorders were in Korean dance (P <0.05). For the obesity index, a similar rate was shown between the different types of dance for the underweight group, but in the normal group, 54.5% were in Korean dance (P <0.05). Most (82.0%) of the group that perceived eating disorders had fears on obesity, while only 53.3% of the non-perceiving group had fears on obesity (P <0.01). Over half (58.3%) of the underweight group had fears on obesity, while 77.2% of the normal group showed fear in that (P <0.05). For necessity of weight loss to do dance performances, 25.0% of the underweight group and 57.9% of the normal group need that (P <0.05). Most of the group that perceived eating disorders (92.0%) answered that they had experience in very low calorie diets, while only 40.0% of the non-perceiving group had experience (P <0.001). For necessity of calorie education, 42.0% of the group that perceived eating disorders and only 20.0% of the non-perceiving group answered is needed (P <0.05). For eating behavior , the group that perceived eating disorders had lower total scores compared to the non-perceiving group (P <0.001), The group that perceived eating disorders showed lower scores for restraint eating (P <0.01) and emotional factors (P <0.001) except by external eating. This study showed that high school girls majoring in dance have high interest in weight control and problems with wrongful body images and eating behaviors, as well as need for calorie education were suggested. Thus, it is necessary to develop and execute a proper weight control education program for the subjects.
Body Image
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Caloric Restriction
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Dancing
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Eating
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Feeding and Eating Disorders
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Feeding Behavior
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Humans
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Obesity
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Thinness
;
Weight Loss
9.Potential Role of Sirtuin as a Therapeutic Target for Neurodegenerative Diseases.
Journal of Clinical Neurology 2009;5(3):120-125
The sirtuins (SIRTs) are protein-modifying enzymes that are distributed ubiquitously in all organisms. SIRT1 is a mammalian homologue of yeast nicotinamide-adenine-dinucleotide-dependent deacetylase silent information regulator 2 (known as Sir2), which is the best-characterized SIRT family member. It regulates longevity in several model organisms and is involved in several processes in mammalian cells including cell survival, differentiation, and metabolism. SIRT1 induction, either by SIRT-activating compounds such as resveratrol, or metabolic conditioning associated with caloric restriction, could have neuroprotective qualities and thus delay the neurodegenerative process, thereby promoting longevity. However, the precise mechanistic liaison between the activation of SIRT and extended healthy aging or delaying age-related diseases in humans has yet to be established.
Aging
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Caloric Restriction
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Cell Survival
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Humans
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Longevity
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Neurodegenerative Diseases
;
Sirtuins
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Stilbenes
;
Yeasts
10.Effects of Very Low Calorie Diet using Meal Replacements on Psychological Factors and Quality of Life in the Obese Women Aged Twenties.
Jiyoung KIM ; Sangyeon KIM ; Kyunga JUNG ; Yukyung CHANG ; Hyeongsuk CHOI ; Sung CHOI ; Mihyeon PARK ; Seonggil HONG ; Sungjoo HWANG
The Korean Journal of Nutrition 2007;40(7):639-649
This study was performed to investigate the effects of very low calorie diet (VLCD) using meal replacements that contain the wild grass extracts based on Samul-tang ingredients on psychological factors and quality of life in the obese women (BMI > or = 25 kg/m2) for four weeks. Seventy five women (20 < or = age < 26) participated in this experiment. Subjects were randomly classified three groups: 1) General diet group (GD group, n = 27) consumed 3 regular meals within 600 kcal/day 2) Meal replacements group (MR group, n = 27) consumed 1 regular meal and 2 meal replacements within 600 kcal/day 3) Herbal Meal replacements group (HMR group, n = 27) consumed 1 regular meal and 2 meal replacements within 600 kcal/day. Physical factors (weight, BMI, fat(%)) of the HMR group significantly decreased more than those of GD and MR groups. Moreover, binge eating habit and environmental factors (surrounding support, emotional reaction, expression of opinion) of the HMR group significantly decreased more than those of GD and MR groups. Psychological factor and quality of life were no significant differences among three groups during the experimental period, because both were significantly decreased in all groups after 4 weeks. Therefore, very low calorie diet using meal replacements that contain the wild grass extracts based on Samul-tang ingredients for 4 weeks was effective on improvement of psychological factor and quality of life as well as weight reduction in the obese premenopausal women.
Bulimia
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Caloric Restriction*
;
Diet
;
Female
;
Humans
;
Meals*
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Poaceae
;
Psychology*
;
Quality of Life*
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Weight Loss