As one of the most active branch disciplines in the systematic biology research field, metabonomics has developed rapidly in recent years and become the research hotspot at home and abroad. The proposal of individualized diagnosis and treatment has emphasized and focused on the effect of internal factors of the human body and individual difference on the diagnosis and treatment of disease. Since metabonomics reflects that under the joint action of genes and the environment, the overall features of individual biological systems and functions states, thus, providing a new train of thought and research platform for studying individualized diagnosis and treatment. Through discussion of the train of thoughts, methods, progress of metabonomics used in studies on individualized difference, we believe that metabonomics technologies have a broad prospect of application in the individualized diagnosis and treatment. It is promising to have significant breakthrough from theory to practice.
Body Constitution ; Humans ; Medicine, Chinese Traditional ; methods ; Metabolomics ; Precision Medicine

The texts on constitution of Miraculous Pivot were analyzed and summarized according to literature study. The findings show that constitution is an important element in acupuncture treatment according to the texts of Miraculous Pivot. Different constitution generates the difference of yin-yang, deficiency or excess of qi and blood which is the important basis for syndrome differentiation of Miraculous Pivot. Therefore, the improvement in constitution is the way to increase the therapeutic effect of acupuncture.
Acupuncture Therapy ; Body Constitution ; Humans ; Medicine, Chinese Traditional

Chinese medicine (CM) has thousands of years of experience in prevention of diseases. As for CM, people's constitution is closely related to their health status, thus recognition of CM constitution is the fundamental and core content of research on constitution types. With development of technologies such as sensors, artificial intelligence and big data, objectification of the four diagnostic methods of CM has gradually matured, bringing changes in the mindset and innovations in technical means for recognition of CM constitution. This paper presents a systematic review of the latest research trends in constitution recognition based on objectification of diagnostic methods in CM.
Humans ; Medicine, Chinese Traditional ; Artificial Intelligence ; Health Status ; Body Constitution

PURPOSE: The purpose of this study was to retrospectively describe the childhood sports activity level of Korean adult men and women and to determine whether a higher level of childhood sports activity was positively associated with adult bone mineral density. METHODS: A cross-sectional study of 100 Korean men (n=40) and women (n=60) was completed. Participants completed a detailed lifetime sports activity questionnaire and had their bone mineral density of the femur and lumbar spine measured using dual energy x-ray densitometry (DEXA). All sports activities were classified into four categories of peak strain score on the basis of ground reaction forces (GRF). RESULTS: During the age of high school, women and men who participated in a high intensity sports activity demonstrated higher bone density in the femur site after adjustment for the effects of body weight, fat body mass, lean body mass, the level of calcium intake, and breast feeding period than those who did not participate in sports activity at all. CONCLUSION: These results highlight the need to participate in high intensity sports activity during high school age as a means of increasing peak bone mass in the femur site.
Sports/*physiology ; Male ; Korea ; Humans ; Female ; Densitometry, X-Ray ; *Bone Density ; Body Constitution ; Body Composition ; Adult

PURPOSE: The purpose of this study was to evaluate the relationship between masseter muscle thickness, facial morphology, and mandibular morphology in Korean adults using ultrasonography. MATERIALS AND METHODS: Ultrasonography was used to measure the masseter muscle thickness bilaterally of 40 adults (20 males, 20 females) and was performed in the relaxed and contracted states. Facial photos and panoramic radiography were used for morphological analyses and evaluated for correlations with masseter muscle thickness. We also evaluated the correlations of age, body weight, stature, and body constitution with masseter muscle thickness. RESULTS: In the relaxing, the masseter was 9.8±1.3 mm in females and 11.3±1.2 mm in males. In the contracted state, it was 12.4±1.4 mm in females and 14.7±1.4 mm in males. Facial photography showed that bizygomatic facial width over facial height was correlated with masseter muscle thickness in both sexes in the relaxed state, and was statistically significantly correlated with masseter muscle thickness in males in the contracted state. In panoramic radiography, correlations were found between anterior angle length and posterior angle length and masseter muscle thickness in females, and between body length and posterior angle length, between anterior angle length and body length, between ramal length and body length, and between body length and condyle length in males. CONCLUSION: Masseter muscle thickness was associated with facial and mandibular morphology in both sexes, and with age in males. Ultrasonography can be used effectively to measure masseter muscle thickness.
Adult ; Body Constitution ; Body Weight ; Female ; Humans ; Male ; Masseter Muscle ; Photography ; Radiography, Panoramic ; Ultrasonography ; Young Adult

OBJECTIVETo study the rules of changes in body constitution of Zhuang students in Guangxi and factors influencing it.

METHODData on body constitution of Zhuang students aged seven to 22 in the year of 2000 were compared with those in 1985.

RESULTSThe average height of Zhuang students increased by 3.80 cm and 2.45 cm for boys and girls in urban areas, respectively from 1985 to 2000 in Guangxi, and by 1.40 cm and 1.32 cm in rural areas, respectively. The average weight increased by 3.58 and 1.90 kg for boys and girls in urban areas, respectively, and by 0.65 kg and 0.02 kg in rural areas, respectively. The average chest circumference increased by 2.09 and 1.28 cm for boys and girls in urban areas, respectively, but in the rural areas, that for boys increased by 0.08 cm and for girls decreased by 0.01 cm. The average systolic blood pressure (BP) decreased by 4.33 mm Hg and 5.06 mm Hg (0.58 kPa and 0.67 kPa) for boys and girls in urban areas, respectively, and by 5.04 mm Hg and 7.03 mm Hg (0.67 kPa and 0.94 kPa) in rural areas, respectively. The average diastolic BP increased by 12.04 mm Hg and 10.84 mm Hg (1.60 kPa and 1.44 kPa) for boys and girls in urban areas, respectively, and by 8.72 mm Hg and 6.54 mm Hg (1.16 kPa and 0.87 kPa) in rural areas, respectively. The average vital capacity increased by 195.15 ml and 109.75 ml, and 23.54 ml and 13.44 ml for urban boys and girls, and rural boys and girls, respectively. The average record of 50 m x 8 run to and for decreased by 5.00 s and 8.79 s for urban boys and girls, respectively, and by 5.27 s and 7.21 s for rural boys and girls, respectively. The average record of 1 000 m run decreased by 19.85 s and 23.88 s for urban and rural boys, respectively, and that of 800 m run decreased by 23.19 s and 6.25 s for urban and rural girls, respectively.

CONCLUSIONSThe results mentioned above suggested that provision of reasonable nutrition and active physical training for the Zhuang students are basic measures to improve their body constitution and promote their levels of growth and development.

Adolescent ; Adult ; Body Constitution ; physiology ; Body Height ; Body Weight ; Child ; China ; ethnology ; Female ; Humans ; Male ; Minority Groups

It was obtained following results on changes of various constitutions in the blood of eleven patient who had massive blood transfusion ( average 14. 6 pints of ACD stored blood) in Seoul Natioeal University Hospital. I. It revealed no definite change of hemoglobin and hematocrit value in two days after massive blood transfusion. 2. Counts in platelets in two days after transfusion decreased from normal value to about I00, 000/mm3 except one case who had transfused 35 pints of bleod. 3. No hypearpotasaemia obser ved in two days after massive transfusion with usage of the blood warmer. 4. Temporary increase of blood glueose revealed with tendency of decrease to normal values in two days after massive transfusion. 5. The pattern of respiratory alkalosis revealed in two days after massive blood transfusion. It implies that the alkalizing agent is not recommended to inject routinely for the transfused patients without checking acid-base status. 6. It is highly recommended to check body temperature, hematocrit, hemoglobin, platelets and values in arterial blood gas and apply the blood warmer for cares in massive transfused patients.
Alkalosis, Respiratory ; Blood Transfusion* ; Body Temperature ; Constitution and Bylaws* ; Hematocrit ; Humans ; Reference Values ; Seoul

PURPOSE: To examine the effects of power walking exercise on fatigue and overweight in college students with Taeumin constitution. METHODS: According to results of the constitution diagnosis (QSCC II), 58 students who were identified as Taeumin, whose BMI was over 23 were assigned to one of three groups. The power walking group walked fast at a speed of 7,000 steps per hour using a pedometer, and the walking group walked at a speed of 5,000 steps per hour. There was no treatment with control group. Each group's fatigue level, blood lipids and body composition before and after the experiment were compared and analyzed. RESULTS: Total fatigue and total cholesterol decreased significantly in the power walking group compared to the walking group and the control group. Weight decreased significantly in the power walking group compared to the control group, and percentage of body fat decreased significantly in both the power walking group and the walking group compared to the control group. CONCLUSION: When power walking exercise was used with overweight Taeumin students, fatigue, blood lipid, weight and percentage of body fat decreased significantly.
Adipose Tissue ; Body Composition ; Cholesterol ; Constitution and Bylaws ; Fatigue ; Humans ; Overweight ; Walking

The aim of modern medicine is transforming from disease to health. Thus the medical model of 4P was proposed in recent years. 4P includes preventive, predictive, personalized, and participatory medical model. In constitution theory of Chinese medicine, there are three main ideas. The first one is: constitutions can be divided to nine types in the Chinese population. Prevention and treatment of disease can be divided according to the constitutional type. This reflects personalized or individualized of 4P. The second one is: certain constitution is correlated to certain disease. So constitution differentiation can be used to predict the occurrence of any kind disease. The third one is: Disease can be prevented through regulating correlated constitutions. And during the course of constitution differentiation, the object of service or patients can participate in the whole course. In summary, the research of Chinese medical constitution embodies the application and practice of 4P medical model. And it provided reference for studying and developing other subjects under the present medical model.
Biomedical Research ; Body Constitution ; Humans ; Medicine, Chinese Traditional ; methods ; Practice Patterns, Physicians'

OBJECTIVETo investigate the differential genes between the qi-stagnation constitution (QSC) and non-QSC, for the sake of disclose the hereditary essence of QSC.

METHODSThe constitution of 3 patients was judged as QSC by criteria for QSC and that of 2 patients was determined as non-QSC by experts according to the gentle constitution related treatise. The differential genes between them were studied using the mRNA differential display revers transcription polymerase chain reaction (DD-RT-PCR).

RESULTSSome differential genes were found (part of them not found in non-QSC, and part was highly expressed in QSC). Among the differential genes, homology was shown between plexin A2-human chromosomal 1q32 (in 98%), notch pre-proteinogen-chromosomal 1q11 (98%), nuclear prelamin A-chromosomal 17q25 (100%), T-cell receptor delta chain-chromosomal 1q24 (99%), neuronal PAS domain protein 3-chromosomal 14q13 (98%), S-phase kinase-associated protein 2-chromosomal 5p12 (99%).

CONCLUSIONSSome differential genes may be existed between QSC and non-QSC.

Body Constitution ; genetics ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Qi ; RNA, Messenger ; genetics