No abstract available.
Anoxia* ; Neurons*

Unidirectional valve (UDV) malfunction causes rebreathing of expired gas during anesthesia. However, the resultant hypercarbia without hypoxemia by UDV malfunction is not easily detected. We experienced a case of severe hypercarbia which caused by sticking expiratory valve at 45 minutes after the induction of anesthesia, in spite of checking UDV function preoperatively. In this case, expiratory UDV malfunction was diagnosed with the change of capnographic waveform. And so, we recommend monitoring of capnographic waveform during every anesthesia, in addition to preoperative UDV checking.
Anesthesia ; Anoxia

Anoxia ; Oxygen* ; Recovery Room*

Hypothesis that hypoxic tumors should be more responsive to the addition of preferential hypoxic cell cytotoxin SR 4233 (tirapazamine) to fractionated irradiation was tested in the mouse SCCVII carcinoma and RIF-1 sarcoma, Model of hypoxic tumor was established using the tumor bed effect; tumors growing in the preirradiated tissue (preirradiated tumors) were more hypoxic than tumors growing in the unirradiated tissue (unirradiated tumors). When the tumors reached a mean volume of 100 mmdegree, both unirradiated and preirradiated tumors were treated with a fractionated course of 62 Gy in 3 days or 8 2.5 Gy in 4days with SR 4233 (0.08 mmlo/kg/injuection) given 30 minutes before each irradiation or without SR 4233. Compared to the unirradiated tumors, hypoxic preirradiated tumors were approximately 5 times more resistant to fractionated irradiation alone but were approximately 5 times more responsive to SR 4233. Addition of SR 4233 potentiated the effect of fractionated irradiation in both unirradiated and preirradiated tumors. Potentiation in the preirradiated tumors was morequal to or greater than that in the unirradiated tumors and seemed to be higher for more fractionated treatment. We confirm the hypothesis in a transplantable mouse tumor. Present results suggest that radioresistance of some hypoxic tumors can be overcome with hypoxic cytotoxin.
Animals ; Anoxia ; Mice ; Sarcoma

Animals ; Anoxia* ; Muscles* ; Rats*

No abstract available.
Anoxia* ; Cochlea* ; Diuretics* ; Guinea*

Pulse oximetry is a noninvasive, reusable device that is being used routinely in anesthesia procedure for monitoring oxygen saturation. This is a very beneficial device that can quickly detect of hypoxia, the most common cause of anesthesia-related death. However, in clinical uses, false desaturation readings are frequently found to be caused by various factors. Such as by the use of intraoperative blue dye, which can falsely decrease oxygen saturation as determined by pulse oximetry. We therefore report our findings concerning prolonged decreased pulse oximetry readings due to the intraoperative use of blue dye subcutaneously.
Anesthesia ; Anoxia ; Oximetry* ; Oxygen ; Reading

We have experienced two cases of one lung anesthesia using univent tube for thoracie surgery. One was the bronchoplasty of the right upper lobe. The other was the left pneumonectomy. The movable endobronchial blocker was introduced into the aimed main bronchus applying the "tube rotation method", In the case of brochoplasty, arterial hypoxemia and hypercarbia has not been corrected well because of the partial obstruction of the carina by endobronchial blocker, but the neurologic complications due to these problems were not encountered. No significant problem has been encountered in the pneumonectomy case. Compared with the standard technique using a double lumen endobronchial tube, this method is simple, easy, effective and less traumatous.
Anesthesia* ; Anoxia ; Bronchi ; Lung* ; Pneumonectomy

Most of perinatological phenomenona and diseases are closely related with immune reaction. Most of initial immune responses occur through innate immunity and most causes, such as mechanical damage, hypoxia, and hyperoxia, are self and microorganisms are non-self, all of which are related with immune reaction concept. However, researches on perinatology are mainly focused on specific one or two causes of perinatal diseases, so often there is limitation to understand the basic concepts and phenomenona of the perinatal diseases. Through understanding of immune reaction concept, we can apply immune reaction theory to researches in perinatology and we can understand phenomenona in perinatology through knowledge of immune reaction. Therefore it is essential to understand historical development of immunology and concept of immune reaction for researches and treatment of perinatology.
Allergy and Immunology ; Anoxia ; Hyperoxia ; Immunity, Innate ; Perinatology*

The site of operation is one of the most significant factors affecting the degree of decreased respiratory function and arterial hypoxemia in the postoperative period. To elucidate the relationship between the site of operation and the postoperative hypoxemia, the authors have performed pre-and post-operative arterial blood gas analysises on the 1st POD through the 4th POD on 30 subjects. The experiment was performed on 3 groups, each of which consisted of 10 subjects; an upper abdominal surgery group, lower abdominal surgery group and extremity surgery group. We have selected only those who have had no preoperative cardiopulmonary problems and excluded those who have developed such complications. The results were as follows; 1) In the upper abdominal surgery group, all postoperative PaO2, values were found to be decreased significantly. 2) In the lower abdominal surgery group, only the 2nd POD PaO2 value was found to be significantly decreased. 3) No demonstrable postoperative change of PaO2, was noted in the extremity surgery group.
Anoxia ; Blood Gas Analysis ; Extremities ; Postoperative Period*