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Volume: 29

1. Cell Autonomous Circadian Systems and Their Relation to Inflammation Page:31—40
2. Development of Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonists in Health Science Page:22—30
3. COVID-19 Vaccine: Critical Questions with Complicated Answers Page:1—10
4. SUV39H1 is a New Client Protein of Hsp90 Degradated by Chaetocin as a Novel C-Terminal Inhibitor of Hsp90 Page:73—82
5. Antaroide, a Novel Natural Nine-Membered Macrolide, Inhibits Melanin Biosynthesis in B16F10 Murine Melanoma Cells Page:98—103
6. Thymoquinone Suppresses Migration of Human Renal Carcinoma Caki-1 Cells through Inhibition of the PGE 2 -Mediated Activation of the EP2 Receptor Pathway Page:64—72
7. KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice Page:41—51
8. The Role of Leptin in the Association between Obesity and Psoriasis Page:11—21
9. Suppressive Effect of Carnosol on Ovalbumin-Induced Allergic Asthma Page:58—63
10. Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice Page:52—57
11. Phloroglucinol Attenuates Ultraviolet B-Induced 8-Oxoguanine Formation in Human HaCaT Keratinocytes through Akt and ErkMediated Nrf2/Ogg1 Signaling Pathways Page:90—97
12. Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes Page:83—89
13. Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine Page:105—126
14. Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells Page:211—219
15. Gene Expression Profiling in the Striatum of Per2 KO Mice Exhibiting More Vulnerable Responses against Methamphetamine Page:135—143
16. Late Passage Cultivation Induces Aged Astrocyte Phenotypes in Rat Primary Cultured Cells Page:144—153
17. Systematic Target Screening Revealed That Tif302 Could Be an OffTarget of the Antifungal Terbinafine in Fission Yeast Page:234—247
18. Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells Page:154—165
19. A Novel Anti-PD-L1 Antibody Exhibits Antitumor Effects on Multiple Myeloma in Murine Models via Antibody-Dependent Cellular Cytotoxicity Page:166—174
20. Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption Page:175—183
21. Endoplasmic Reticulum Stress-Mediated p62 Downregulation Inhibits Apoptosis via c-Jun Upregulation Page:195—204
22. KAT8/MOF-Mediated Anti-Cancer Mechanism of Gemcitabine in Human Bladder Cancer Cells Page:184—194
23. Ibuprofen Increases the Hepatotoxicity of Ethanol through Potentiating Oxidative Stress Page:205—210
24. Oleanolic Acid Protects the Skin from Particulate Matter-Induced Aging Page:220—226
25. Antineuroinflammatory Effects of 7,3’,4’-Trihydroxyisoflavone in Lipopolysaccharide-Stimulated BV2 Microglial Cells through MAPK and NF-κB Signaling Suppression Page:127—134
26. Mechanisms of Resorcinol Antagonism of Benzoapyrene-Induced Damage to Human Keratinocytes Page:227—233
27. Erratum to "Melatonin-Induced PGC-1α Improves Angiogenic Potential of Mesenchymal Stem Cells in Hindlimb Ischemia" Biomol. Ther. 28 (2020) 240-249 Page:454—454
28. Erratum to "Cripto Enhances Proliferation and Survival of Mesenchymal Stem Cells by Up-Regulating JAK2/STAT3 Pathway in a GRP78-Dependent Manner" Biomol. Ther. 26 (2018) 464-473 Page:452—453
29. Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches Page:353—364
30. Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors Page:392—398
31. Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22 Page:384—391
32. Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease Page:373—383
33. Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management Page:365—372
34. 4-CMTB Ameliorates Ovalbumin-Induced Allergic Asthma through FFA2 Activation in Mice Page:427—433
35. Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene Page:399—409
36. Effects of the Combination of Evogliptin and Leucine on Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice Page:419—426
37. Salicylamide Enhances Melanin Synthesis in B16F1 Melanoma Cells Page:445—451
38. Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives Page:410—418
39. Differential Sensitivity of Wild-Type and BRAF-Mutated Cells to Combined BRAF and Autophagy Inhibition Page:434—444
40. Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS Page:295—302
41. Multifactorial Traits of SARS-CoV-2 Cell Entry Related to Diverse Host Proteases and Proteins Page:249—262
42. Antiviral Efficacy of Pralatrexate against SARS-CoV-2 Page:268—272
43. Recent Advances of Therapeutic Targets for the Treatment of Periodontal Disease Page:263—267
44. 3’-O-Acetyl-24-Epi-7,8-Didehydrocimigenol-3-O-β-DXylopryranoside Decreases Amyloid Beta Production in Amyloid Precursor Protein-Transfected HeLa Cells Page:290—294
45. Differential Signaling and Virus Production in Calu-3 Cells and Vero Cells upon SARS-CoV-2 Infection Page:273—281
46. Inhibition of COX-2 Impairs Colon Cancer Liver Metastasis through Reduced Stromal Cell Reaction Page:342—351
47. SP-8356, a (1S)-(-)-Verbenone Derivative, Inhibits the Growth and Motility of Liver Cancer Cells by Regulating NF-κB and ERK Signaling Page:331—341
48. Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway Page:321—330
49. Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2by Targeting the Spike S2 Subunit Page:282—289
50. Suppression of Foxo3-Gatm by miR-132-3p Accelerates Cyst Formation by Up-Regulating ROS in Autosomal Dominant Polycystic Kidney Disease Page:311—320
51. Kaempferol Regulates the Expression of Airway MUC5AC Mucin Gene via IκBα-NF-κB p65 and p38-p44/42-Sp1 Signaling Pathways Page:303—310
52. Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer Page:506—518
53. Bioactive Lipids and Their Derivatives in Biomedical Applications Page:465—482
54. Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders Page:455—464
55. Hyaluronic Acid Increases Anti-Inflammatory Efficacy of Rectal 5-Amino Salicylic Acid Administration in a Murine Colitis Model Page:536—544
56. Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice Page:483—491
57. Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo Page:551—561
58. Anticancer Activity of Indeno1,2-b-Pyridinol Derivative as a New DNA Minor Groove Binding Catalytic Inhibitor of Topoisomerase IIα Page:562—570
59. Change in Cationic Amino Acid Transport System and Effect of Lysine Pretreatment on Inflammatory State in Amyotrophic Lateral Sclerosis Cell Model Page:498—505
60. Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay Page:519—526
61. Conformational Dynamics of Sclerostin-LRP6 Complex Analyzed by HDX-MS Page:527—535
62. ER71/ETV2 Promotes Hair Regeneration from Chemotherapeutic Drug-Induced Hair Loss by Enhancing Angiogenesis Page:545—550
63. Suppressive Effect of CYM50358 S1P4 Antagonist on Mast Cell Degranulation and Allergic Asthma in Mice Page:492—497
64. Erratum to "Melatonin-Induced PGC-1α Improves Angiogenic Potential of Mesenchymal Stem Cells in Hindlimb Ischemia" Biomol. Ther. 28 (2020) 240-249 Page:454—454
65. Erratum to "Cripto Enhances Proliferation and Survival of Mesenchymal Stem Cells by Up-Regulating JAK2/STAT3 Pathway in a GRP78-Dependent Manner" Biomol. Ther. 26 (2018) 464-473 Page:452—453
66. Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches Page:353—364
67. Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors Page:392—398
68. Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22 Page:384—391
69. Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease Page:373—383
70. Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management Page:365—372
71. 4-CMTB Ameliorates Ovalbumin-Induced Allergic Asthma through FFA2 Activation in Mice Page:427—433
72. Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene Page:399—409
73. Effects of the Combination of Evogliptin and Leucine on Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice Page:419—426
74. Salicylamide Enhances Melanin Synthesis in B16F1 Melanoma Cells Page:445—451
75. Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives Page:410—418
76. Differential Sensitivity of Wild-Type and BRAF-Mutated Cells to Combined BRAF and Autophagy Inhibition Page:434—444
77. Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS Page:295—302
78. Multifactorial Traits of SARS-CoV-2 Cell Entry Related to Diverse Host Proteases and Proteins Page:249—262
79. Antiviral Efficacy of Pralatrexate against SARS-CoV-2 Page:268—272
80. Recent Advances of Therapeutic Targets for the Treatment of Periodontal Disease Page:263—267
81. 3’-O-Acetyl-24-Epi-7,8-Didehydrocimigenol-3-O-β-DXylopryranoside Decreases Amyloid Beta Production in Amyloid Precursor Protein-Transfected HeLa Cells Page:290—294
82. Differential Signaling and Virus Production in Calu-3 Cells and Vero Cells upon SARS-CoV-2 Infection Page:273—281
83. Inhibition of COX-2 Impairs Colon Cancer Liver Metastasis through Reduced Stromal Cell Reaction Page:342—351
84. SP-8356, a (1S)-(-)-Verbenone Derivative, Inhibits the Growth and Motility of Liver Cancer Cells by Regulating NF-κB and ERK Signaling Page:331—341
85. Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway Page:321—330
86. Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2by Targeting the Spike S2 Subunit Page:282—289
87. Suppression of Foxo3-Gatm by miR-132-3p Accelerates Cyst Formation by Up-Regulating ROS in Autosomal Dominant Polycystic Kidney Disease Page:311—320
88. Kaempferol Regulates the Expression of Airway MUC5AC Mucin Gene via IκBα-NF-κB p65 and p38-p44/42-Sp1 Signaling Pathways Page:303—310
89. Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer Page:506—518
90. Bioactive Lipids and Their Derivatives in Biomedical Applications Page:465—482
91. Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders Page:455—464
92. Hyaluronic Acid Increases Anti-Inflammatory Efficacy of Rectal 5-Amino Salicylic Acid Administration in a Murine Colitis Model Page:536—544
93. Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice Page:483—491
94. Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo Page:551—561
95. Anticancer Activity of Indeno1,2-b-Pyridinol Derivative as a New DNA Minor Groove Binding Catalytic Inhibitor of Topoisomerase IIα Page:562—570
96. Change in Cationic Amino Acid Transport System and Effect of Lysine Pretreatment on Inflammatory State in Amyotrophic Lateral Sclerosis Cell Model Page:498—505
97. Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay Page:519—526
98. Conformational Dynamics of Sclerostin-LRP6 Complex Analyzed by HDX-MS Page:527—535
99. ER71/ETV2 Promotes Hair Regeneration from Chemotherapeutic Drug-Induced Hair Loss by Enhancing Angiogenesis Page:545—550
100. Suppressive Effect of CYM50358 S1P4 Antagonist on Mast Cell Degranulation and Allergic Asthma in Mice Page:492—497
101. Erratum to "Modulation of Human Cardiac Progenitors via Hypoxia-ERK Circuit Improves their Functional Bioactivities" Biomol. Ther. 21 (2013) 196-203 Page:697—697
102. Lipid Metabolism, Disorders and Therapeutic Drugs – Review Page:596—604
103. Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling Page:658—666
104. Small Molecule Drug Candidates for Managing the Clinical Symptoms of COVID-19: a Narrative Review Page:571—581
105. Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation Page:650—657
106. Eriodictyol Inhibits the Production and Gene Expression of MUC5AC Mucin via the IκBα-NF-κB p65 Signaling Pathway in Airway Epithelial Cells Page:637—642
107. Systematic Review of Recent Lipidomics Approaches Toward Inflammatory Bowel Disease Page:582—595
108. Eupafolin Suppresses P/Q-Type Ca2+ Channels to Inhibit Ca2+ / Calmodulin-Dependent Protein Kinase II and Glutamate Release at Rat Cerebrocortical Nerve Terminals Page:630—636
109. Neuroprotective Effect of Astersaponin I against Parkinson’s Disease through Autophagy Induction Page:615—629
110. Hair Growth Promotion by δ-Opioid Receptor Activation Page:643—649
111. AR-mTOR-SRF Axis Regulates HMMR Expression in Human Prostate Cancer Cells Page:667—677
112. Luteolin Promotes Apoptosis of Endometriotic Cells and Inhibits the Alternative Activation of Endometriosis-Associated Macrophages Page:678—684
113. Neuronal Autophagy: Characteristic Features and Roles in Neuronal Pathophysiology Page:605—614
114. Suppression of Lipopolysaccharide-Induced Inflammatory and Oxidative Response by 5-Aminolevulinic Acid in RAW 264.7 Macrophages and Zebrafish Larvae Page:685—696