WPRIM Management System> DCMS> Acta Pharmaceutica Sinica B> 2016> 6> 5

Volume: 6 Issue: 5

1. PBPK modeling and simulation in drug research and development. Page:430—440
2. Editorial of Virtual Special Issue on Progress in Medicinal Chemistry. Page:510—511
3. 17-Estradiol up-regulates UDP-glucuronosyltransferase 1A9 expressionestrogen receptor. Page:504—509
4. Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice. Page:492—503
5. Characterizing drug-metabolizing enzymes and transporters that areCAR-target genes in mouse intestine. Page:475—491
6. Effect of age on the pharmacokinetics of polymorphic nimodipine in rats after oral administration. Page:468—474
7. Tissue distribution and tumor uptake of folate receptor-targeted epothilone folate conjugate, BMS-753493, in CD2F1 mice after systemic administration. Page:460—467
8. Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver. Page:453—459
9. A brief history of the discovery of PXR and CAR as xenobiotic receptors. Page:450—452
10. variants: the impact on drug metabolism and therapeutic responses. Page:441—449
11. Exposure to inorganic arsenic can lead to gut microbe perturbations and hepatocellular carcinoma. Page:426—429
12. Insights into CYP2B6-mediated drug-drug interactions. Page:413—425
13. Fatty liver diseases, bile acids, and FXR. Page:409—412
14. Crosstalk of HNF4with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids. Page:393—408
15. Isoniazid metabolism and hepatotoxicity. Page:384—392
16. An update on the role of intestinal cytochrome P450 enzymes in drug disposition. Page:374—383
17. Renal drug transporters and their significance in drug-drug interactions. Page:363—373
18. Advanced knowledge in drug metabolism and pharmacokinetics. Page:361—362
19. Editor Profiles: Guest Editors of Special Issue on Drug Metabolism and Pharmacokinetics. Page:359—360