| 1. α4β2-Nicotine acetylcholine receptor: advances in relevant diseases and drugs |
Page:1—8 |
| 2. Progress in understanding hepatic fibrosis and renal fibrosis based on the gut-liver-kidney axis |
Page:9—20 |
| 3. Research progress on dual PDE3/4 inhibitors for the treatment of respiratory diseases |
Page:70—79 |
| 4. Research progress on ATP citrate lyase (ACLY) inhibitors for decreasing blood lipids |
Page:80—91 |
| 5. Overexpressing of chalcone isomerase (CHI) gene enhances flavonoid accumulation in Glycyrrhiza uralensis hairy roots |
Page:319—327 |
| 6. Glaucocalyxin A attenuates allergic responses by inhibiting mast cell degranulation through HMGB1/TLR4/NF-κB signaling pathways |
Page:201—207 |
| 7. Effect of hypoxia on drug metabolizing enzymes and transporters and the role of microRNA |
Page:50—60 |
| 8. Evaluation of the preventive effect of DL0805-2 against monocrotaline induced rat pulmonary arterial hypertension |
Page:208—216 |
| 9. Research and application of nanometer black phosphorus in phototherapy and drug carrier |
Page:178—189 |
| 10. Research on the lipid-lowering effect of traditional Chinese medicine using lipidomics technology |
Page:61—69 |
| 11. The possible mechanisms of Erhuang decoction in the treatment of acute lung injury based on network pharmacology |
Page:244—256 |
| 12. Application of natural deep eutectic solvents in pharmaceutics |
Page:146—157 |
| 13. Major progress in tumor accumulation and penetration of nanomedicine |
Page:138—145 |
| 14. Research progress of in vitro-in vivo correlation of injectable polylactide-polyglycolide microspheres |
Page:158—168 |
| 15. The mechanism of androgen independent signaling pathway in castration-resistant prostate cancer and the research progress on related drugs |
Page:21—28 |
| 16. Characterization and principal component analysis of functionality-related characteristics of hydroxypropyl methylcellulose type 2208 |
Page:314—318 |
| 17. Analysis of technical difficulties and new strategies of oral liquid pharmaceutical preparation for children |
Page:130—137 |
| 18. Preparation and quality evaluation of fluorocarbon microemulsion-based gel loaded with both 5-aminolevulinic acid and carbon dioxide |
Page:306—313 |
| 19. Prospects for histone deacetylase inhibitors as antidepressants |
Page:29—36 |
| 20. Progress on application of central composite design-response surface methodology in optimization of preparations in China |
Page:169—177 |
| 21. Strategy to delay the progression of chronic kidney disease by targeting gut microbiota and uremic toxins metabolism pathway |
Page:37—49 |
| 22. Cloning and characterization of two rhamnose synthases from Sorbus aucuparia |
Page:328—335 |
| 23. Comparative study on the effects of total ginkgo flavonol glycosides and total ginkgolides on neurofunctional recovery in mice with subacute stroke |
Page:231—243 |
| 24. Advances in characterization of pharmaceutical polymorphisms by vibrational spectroscopy |
Page:102—112 |
| 25. Mechanism of inhibiting proliferation of tumor cells by a new tetrahydroisoquinoline compound SYT-1 |
Page:217—223 |
| 26. Mechanisms of baicalein inhibiting metastasis of esophageal squamous cell carcinoma through ERK/ELK-1/Snail signaling pathway |
Page:224—230 |
| 27. In vitro inhibition by 79 herb injectables of nine human cytochrome P450 isoenzymes: a systematic evaluation of herb-drug interactions |
Page:274—282 |
| 28. Clinical metabolomics research on Xiaozhang Tie with the umbilical compress therapy for cirrhotic ascites |
Page:257—265 |
| 29. A new polyacetylene from the stems and leaves of Chrysanthemum morifolium Ramat |
Page:283—288 |
| 30. Advances in high-resolution mass spectrometric-based data-mining technologies for detecting and characterizing the components and metabolites of Chinese materia medica |
Page:113—129 |
| 31. Relationship between fatigue caused by type 2 diabetes mellitus and 5-HT degradation in skeletal muscle |
Page:190—200 |
| 32. Chemical constituents of triterpenoid saponins from Glycyrrhiza glabra |
Page:289—295 |
| 33. Quantitative identification of TCM Q-markers based on analytical hierarchy and the entropy weight comprehensive method by taking Shaoyao Gancao decoction as an example |
Page:296—305 |
| 34. Natural products in the prevention and treatment of melanoma |
Page:92—101 |
| 35. Clinical case analysis and disassembled prescription study of liver injury related to Xianling Gubao |
Page:266—273 |
| 36. Pharmacokinetic/pharmacodynamic modeling of the antitumor action of bispecific CD3/EpCAM antibody M701 in human colorectal cancer xenograft mice |
Page:538—544 |
| 37. Updated research progress of selective PPARγ modulators |
Page:352—359 |
| 38. Research progress on small molecule kinase inhibitors |
Page:414—431 |
| 39. Metabolic module identification and biological mechanism of Xiaoyaosan for treatment of depression |
Page:528—537 |
| 40. Current status and future of drugs targeting platelets-tumor cells interactions |
Page:360—367 |
| 41. Progress in tumor microenvironment responsive nano-platforms for cancer theranostics |
Page:465—475 |
| 42. Research progress in multi-targeted anti-tumor natural products |
Page:403—413 |
| 43. Preparation and anti-tumor activity of a novel antibody-drug conjugate 607-LDM |
Page:496—502 |
| 44. Research progress on metabolism and efficacy of small molecular prodrug nanosystems responsive to tumor redox microenvironment |
Page:476—486 |
| 45. Lead compound optimization strategy (8) - drug transporters and related drug design strategies |
Page:432—444 |
| 46. Mechanistic study on the solubility enhancement of puerarin by coamorphous technology |
Page:585—592 |
| 47. Advances in the optimization of the linker in proteolysis-targeting chimeras (PROTAC) |
Page:445—455 |
| 48. Research advances on the protective effects and mechanism of salvianolic acids against ischemic heart disease |
Page:368—373 |
| 49. Preparation and enhanced photodynamic therapy of supramolecular nanoparticles to overcome tumor hypoxia |
Page:593—603 |
| 50. Research advances in the effect and utilization of protein corona on the circulation of nanoparticles in vivo |
Page:487—495 |
| 51. Identification and application of biomarkers in life cycle of drugs |
Page:456—464 |
| 52. Cloning and bioinformatic analysis of the 3-ketoacyl-CoA synthase gene in Coix lacryma-jobi L. |
Page:610—617 |
| 53. Complete plastid genomes of Bupleurum chinense DC. and B. boissieuanum H. Wolff, with comparative and phylogenetic analyses of medicinal Bupleurum species |
Page:618—629 |
| 54. Simultaneous quantitative analyses of six components in Astragalus membranaceus based on HPLC-CAD and quantitative analysis of multi-components with a single-marker |
Page:557—564 |
| 55. Value assignment study on bioactivity of monoclonal antibody working reference standard |
Page:565—569 |
| 56. Identification of small molecule sirtuin-1 inhibitors for treating acute myeloid leukemia based on molecular docking, quantitative structure-activity relationships and molecular dynamics |
Page:545—552 |
| 57. Preparation, characterization and improved solubility of ticagrelor salts |
Page:570—576 |
| 58. Recent advancement in targeting the KRAS-G12C mutant for cancer therapy |
Page:374—382 |
| 59. Construction of a drug screening model for miscarriage from induced pluripotent stem cells in vitro |
Page:503—510 |
| 60. A new dimeric benzylisoquinoline alkaloid from Corydalis yanhusuo |
Page:553—556 |
| 61. Cloning and expression analysis of chalcone isomerase from Aquilaria sinensis |
Page:630—638 |
| 62. Rutaecarpine exerted anti-osteroporosis |
Page:511—519 |
| 63. Bruceantin inhibits proliferation, migration and invasion of non-small cell lung cancer H1299 cells by up-regulating miR-29a-3p |
Page:520—527 |
| 64. Synaptic pruning mediated by glia in Alzheimer's disease |
Page:383—390 |
| 65. Role of gut microbiota in the treatment of ulcerative colitis with traditional Chinese medicine |
Page:391—402 |
| 66. Establishment of a cocrystal characterization method for sacubitril valsartan sodium |
Page:577—584 |
| 67. Preparation and targeting capability of corona forming in human ovarian plasma |
Page:604—609 |
| 68. First-in-class small molecule drugs in 2020 |
Page:341—351 |
| 69. Current status of treatment and drug discovery for neuropathic pain |
Page:679—688 |
| 70. Baicalein reduces Aβ25-35-induced PC12 cell damage by inhibiting the JAK2/STAT1 pathway |
Page:771—777 |
| 71. Inhibition of exosomes-mediated melanoma metastasis by icaritin |
Page:778—785 |
| 72. Review of novel compounds that act on the AT2 receptor |
Page:711—722 |
| 73. Sempervirine inhibits proliferation of human glioma U251 cells in vitro and in vivo |
Page:786—792 |
| 74. Research progress on indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors |
Page:723—733 |
| 75. Advances in drug research targeting the Wnt signaling pathway in colorectal cancer |
Page:689—695 |
| 76. Minimally invasive dissolving microneedles for ocular brinzolamide delivery |
Page:849—854 |
| 77. Anti-dengue virus activity of natural podocarpane-type diterpenoid in vitro |
Page:793—798 |
| 78. Gelation of small molecule amorphous drugs |
Page:855—864 |
| 79. Development and application of a chemical transformational method for the indirect measurement of ligustilide content in Angelica sinensis |
Page:841—848 |
| 80. Biphasic dissolution test and its application in the evaluation of poorly soluble drug preparations |
Page:743—750 |
| 81. Multi-template molecularly imprinted solid phase extraction and its application in the extraction and separation of multi-components from traditional Chinese medicine |
Page:751—760 |
| 82. 8-Azaguanine-induced autophagy contributes to its chemoresistance in hepatic cancer cells |
Page:799—807 |
| 83. The mechanism of NLRP3 inflammasome affecting vascular aging and the development of related drugs |
Page:696—702 |
| 84. Research progress on the interaction of neuropsychiatric drugs with the gut microbiota |
Page:643—653 |
| 85. Research progress of focused ultrasound combined with microbubbles to open blood-brain barrier for brain-targeted delivery |
Page:761—770 |
| 86. The mechanism of action of Pudilan Xiaoyan oral liquid against LPS-induced acute respiratory infection in mice based on biological network analysis and metabolomics |
Page:816—822 |
| 87. A new cadinane-type sesquiterpenoid from Commiphora myrrha |
Page:831—834 |
| 88. Model-informed drug development for immune checkpoint inhibitors |
Page:734—742 |
| 89. The diversity of endophytic fungi in endangered medicinal material Daphnes Cortex as determined by high-throughput sequencing technology |
Page:872—878 |
| 90. Mitochondrial retrograde signaling: a new option for the treatment of mitochondrially related diseases |
Page:661—668 |
| 91. The combined therapeutic effects of 5-aminolevulinic acid cubic liquid crystal and light needles for basal cell cancer |
Page:865—871 |
| 92. The protective effects and mechanism of Alismatis Rhizoma extracts against senecionine-induced acute liver injury in mice |
Page:823—830 |
| 93. Research progress of neutrophil extracellular traps and related targeted drugs for the treatment of inflammatory diseases |
Page:669—678 |
| 94. The compound cell model-based evaluation for idiosyncratic liver injury of Cis-SG and Trans-SG |
Page:808—815 |
| 95. DNA barcoding identification of commercial decoctions in traditional Chinese medicine |
Page:879—889 |
| 96. Synthesis and antibacterial activities of novel sulfonamide derivatives containing a fused-ring |
Page:835—840 |
| 97. The regulatory role of E2F1 in prostate cancer |
Page:654—660 |
| 98. Research progress on STAT protein inhibitors in the treatment of lymphoma |
Page:703—710 |
| 99. Research on polymer impurities in cefazolin sodium raw materials and products |
Page:1677—1682 |
| 100. Sinomenine promotes paired immunoglobulin-like receptor B expression to restrain macrophage classic activation |
Page:1644—1652 |
| 101. Progress in antitumor activity of baicalin |
Page:1537—1543 |
| 102. The latest research progress of torpor occurrence mechanism |
Page:1532—1536 |
| 103. Research progress of KRAS inhibitors |
Page:1562—1570 |
| 104. Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery system |
Page:1591—1598 |
| 105. The clinical application and development of traditional antitumor drugs |
Page:1551—1561 |
| 106. In vitro lipolysis process and lipolysis mechanism of testosterone undecanoate type Ⅲ lipid formulations |
Page:1696—1703 |
| 107. Research progress in mechanisms of idiosyncratic drug-induced liver injury mediated by inflammatory stress |
Page:1544—1550 |
| 108. Catalpol inhibits cell apoptosis through alleviating endoplasmic reticulum stress in nonalcoholic fatty liver disease |
Page:1634—1643 |
| 109. Recent progress in targeting degradation of FAK based on PROTAC |
Page:1571—1579 |
| 110. Research progress of chemokines and their receptors in breast cancer |
Page:1521—1531 |
| 111. Preparation and stability evaluation of artemether-loaded mixed micelles composed of the sodium glycocholate and soybean lecithin |
Page:1704—1711 |
| 112. Advances in natural products that target the tumor microenvironment |
Page:1580—1590 |
| 113. Pharmacodynamic material basis and mechanism of Fufang Yuxingcao Mixture for the treatment of heat-clearing and detoxification based on network pharmacology |
Page:1653—1662 |
| 114. The intestinal absorption characteristics of five active components in Lizhong Decoction |
Page:1689—1695 |
| 115. Formulation and sterilization assessment of kanamycin sulfate injection based on impurity profiles |
Page:1683—1688 |
| 116. Chlorogenic acid down-regulates the expression of PD-L1 in esophageal squamous cell carcinoma via IFN-γ signaling pathway |
Page:1599—1605 |
| 117. The analysis of unconventional research projects and common problems in the in vitro consistency evaluation of oral solid generic drugs |
Page:1739—1744 |
| 118. The role of renal 5-hydroxytryptamine synthesis and degradation in hyperglycemia-induced kidney injury |
Page:1612—1620 |
| 119. Effects of temperature, pH, and H2O2 on the growth and biofilm formation of attenuated Salmonella VNP20009 |
Page:1606—1611 |
| 120. Ferulate 5-hydroxylase gene (F5H) regulation of glycyrrhizic acid biosynthesis determined by gene overexpression and knockout |
Page:1719—1726 |
| 121. Preparation and evaluation of methotrexate sustained-release particles using crosslinked cyclodextrin metal-organic frameworks |
Page:1712—1718 |
| 122. The anti-hyperuricemic effects of compound CC18022 targeting xanthine oxidase |
Page:1621—1626 |
| 123. Four new dammarane-type triterpenoid saponins from Gynostemma longipes C.Y.Wu |
Page:1670—1676 |
| 124. Construction and application of recombinant human UDP-glucuronosyltransferases expression systems |
Page:1727—1738 |
| 125. Study on blood apolipoprotein as a potential biomarker of neurodegenerative diseases |
Page:1513—1520 |
| 126. Protective effects of the total glycosides of Cistanche deserticola Y. C. Ma in alcoholic liver injury in mice |
Page:2528—2535 |
| 127. Lipid metabolism and hematological malignancies |
Page:2456—2463 |
| 128. Suppression of OCT2/MRP2 decreases kidney injury and enhances the chemosensitivity of co-administration of cisplatin and astragaloside IV |
Page:2536—2543 |
| 129. The mechanism by which Peganum harmala L. inhibits high glucose-induced tube formation in endothelial cells |
Page:2544—2552 |
| 130. Identification of Fritillaria taibaiensis and its relatives by real-time PCR with a TaqMan-MGB probe |
Page:2577—2583 |
| 131. Advances in small molecular inhibitors of IL-6/STAT3 signaling pathway |
Page:2472—2484 |
| 132. Advances in the pathogenesis of depression based on purinergic system and purine metabolism |
Page:2464—2471 |
| 133. Research progress of glucagon receptor related compounds |
Page:2447—2455 |
| 134. Analysis of projects without nanotechnology funded by National Natural Science Foundation of China in the field of pharmaceutics from 2001 to 2020 |
Page:2522—2527 |
| 135. Advances in dendritic cell-based vaccine delivery |
Page:2485—2494 |
| 136. Advances in drug delivery strategies against Helicobacter pylori |
Page:2495—2504 |
| 137. Interaction study of the antibacterial peptide urumin with the H1N1 HA protein of influenza A virus |
Page:2553—2560 |
| 138. The mechanism of toxicity enhancement with the combination of Flos Genkwa and Radix et Rhizoma Glycyrrhizae based on the solubilization of glycyrrhizic acid |
Page:2561—2566 |
| 139. Molecular markers based upon whole chloroplast genomes and identifying alpine Gentiana waltonii and G. lhassica (Gentianaceae) |
Page:2584—2591 |
| 140. Analysis of monosaccharide composition and monosaccharide ratio in propylene glycol alginate sodium sulphate drugs by high performance anion exchange chromatograghy -pulsed amperometric detection |
Page:2346—2351 |
| 141. Advancements in stabilization technologies for membrane protein and its application in drug screening |
Page:2325—2334 |
| 142. Development and validation of ELISA method for detection of human signal regulatory protein α-anti-CD20 mouse chimeric antibody fusion protein IMM0306 in human serum |
Page:2367—2371 |
| 143. Determination method of deamidation impurities in cobratide using mass spectrometry technique |
Page:2352—2359 |
| 144. Pharmacokinetics of FGF21-164 fusion protein in mice using UHPLC-MS/MS method |
Page:2372—2377 |
| 145. N-Glycans and intact glycopeptide-based characterization of N-glycosylation of monoclonal antibody drugs |
Page:2360—2366 |
| 146. Comparative study on the protective effect of Salvia miltiorrhiza and Anemarrhena asphodeloides on AD cell model using UHPLC-QTOF/MS based cell metabolomics |
Page:2394—2402 |
| 147. The mechanism of Er-xian Decoction in regulating lipid metabolism disorders on bilateral ovariectomized rats based on metabolomics study |
Page:2403—2409 |
| 148. Mechanism investigation on the enhanced anti-hepatic fibrosis effects in rats of Fructus Corni after wine-processing based on plasma metabonomics |
Page:2410—2418 |
| 149. Application of nano-bionic drug delivery system based on macrophages in tumor therapy |
Page:2505—2512 |
| 150. Determination of insulin lispro in rat plasma by LC-MS/MS and its application in a pharmacokinetics study |
Page:2383—2388 |
| 151. Advances in the bioanalysis of therapeutic oligonucleotides |
Page:2335—2345 |
| 152. Development and validation of antibody sandwich enzyme-linked immunosorbent assay method for quantitation of GeXIVA1,2 in plasma of rats and Beagle dogs |
Page:2378—2382 |
| 153. Cyclization of α-conotoxin A10LPnIA with lysine assisted cyanuric chloride linker |
Page:2567—2572 |
| 154. Tert-butanol application and related research progress in biomedicine |
Page:2513—2521 |
| 155. Multi-compound pharmacokinetic research on Chinese herbal medicines: identifying potentially therapeutic compounds and characterizing their disposition and pharmacokinetics |
Page:2426—2446 |
| 156. Establishment of high-resolution bioassay profiling platform to screen α-glucosidase inhibitors from Malus hupehensis |
Page:2419—2425 |
| 157. Development of a fast and sensitive method for direct analysis of insulin aspart in human plasma |
Page:2389—2393 |
| 158. Analysis of the research status and intervention strategies for the treatment of hepatic encephalopathy based on gut microbiota regulation |
Page:895—905 |
| 159. Regulatory effect of total phenolic acid from the stems and leaves of Salvia miltiorrhiza Bge. on intestinal microflora and short-chain fatty acids in type 2 diabetic nephropathy mice |
Page:1035—1048 |
| 160. Compatibility of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos regulate insulin signaling pathway and alleviate insulin resistance in mice |
Page:1049—1056 |
| 161. Research progress on the antitumor effect of flavonoid derivatives |
Page:913—923 |
| 162. The molecular mechanism of ginkgolide B regulating the expression of long-chain fatty acid metabolism-related proteins and antioxidant therapy for non-alcoholic fatty liver disease |
Page:1057—1062 |
| 163. Recent advances of MDM2-p53 inhibitors |
Page:983—995 |
| 164. Ligand fishing: a strategy for rapidly screening bioactive compounds from organism extracts |
Page:996—1005 |
| 165. Association of depression with dietary fatty acids and the progress of mechanism research |
Page:906—912 |
| 166. Evaluation of non-clinical anxiety disorder models |
Page:949—965 |
| 167. Research progress in tumor microenvironmentally modulating nanostructures |
Page:1016—1024 |
| 168. Current status of treatment and drug discovery for epilepsy |
Page:924—938 |
| 169. Advances of Lefamulin: a new pleuromutilin antibiotic |
Page:1006—1015 |
| 170. Changes in the intestinal flora of rats under high altitude hypoxia |
Page:1100—1108 |
| 171. The mechanism of tilianin against ischemia-reperfusion injury of H9c2 cells |
Page:1070—1078 |
| 172. Cloning and expression characteristics of a transcription factor gene RpMYB4 in Rheum palmatum L. |
Page:1170—1177 |
| 173. The protective effect of salvianolic acid B against senecionine-induced hepatotoxicity in mice |
Page:1079—1085 |
| 174. Optimization of process parameters of 3D printed clozapine dispersive tablets and establishment of personalized dose model |
Page:1155—1162 |
| 175. Effects of metal or dissolving microneedles and its parameters of operation on the formation and closure of skin microchannels |
Page:1163—1169 |
| 176. Research progress of aristolochic acids and their biomarkers |
Page:972—982 |
| 177. Analysis of the soil microbial community of Cistanche deserticola and Cynomorium songaricum in the saline-alkali soil of Ebinur Lake |
Page:1178—1187 |
| 178. Interferon-regulatory factors regulate macrophage polarization and its role in diseases |
Page:939—948 |
| 179. The effect of metformin on lipid disorders as measured by nuclear magnetic metabolomics and metabolic flux analysis |
Page:1109—1119 |
| 180. The anti-atherosclerotic effect and mechanism of puerarin |
Page:966—971 |
| 181. Tolcapone derivative PCDNA inhibits Aβ42 fibrillogenesis and reduces its cytotoxicity |
Page:1063—1069 |
| 182. Design and synthesis of tetrazine bioorthogonal fluorogenic probes |
Page:1086—1095 |
| 183. Strategies and reflections on platelet-based targeted therapy for tumor |
Page:1025—1034 |
| 184. Analysis of triterpenoic acids in different medicinal parts of Poria cocos (Schw.) Wolf using supercritical fluid chromatography |
Page:1120—1126 |
| 185. Ginkgo biloba extract ameliorates streptozotocin-induced diabetes in rats as measured by non-targeted metabolomics |
Page:1127—1136 |
| 186. The protective effect of drug-containing serums and polar extracts of Erzhi Wan on H2O2-induced hepatocyte senescence |
Page:1137—1146 |
| 187. A new dimeric dehydrocorydaline alkaloid from vinegar-prepared Corydalis yanhusuo |
Page:1096—1099 |
| 188. Wuzhi Tablet protects against APAP-induced liver injury at different pretreated intervals in mice |
Page:1147—1154 |
| 189. Transcriptome analysis and exploration of genes involved in the biosynthesis of iridoids in Gentiana crassicaulis (Gentianaceae) |
Page:2005—2014 |
| 190. FGFR4: a promising therapeutic target for liver cancer |
Page:1832—1844 |
| 191. Research progress of antioxidant drugs in myocardial ischemia-reperfusion injury |
Page:1845—1855 |
| 192. The mechanism of RCE-4, an active ingredient of Reineckia carnea, in combination with celecoxib on the anti-proliferation of cervical cancer Ca Ski cells |
Page:1911—1920 |
| 193. Research progress of effective components of traditional Chinese medicine in anti-aging and anti-tumor mechanism |
Page:1856—1864 |
| 194. Application and mechanism of nanomedicine in antifungal infection therapy |
Page:1893—1901 |
| 195. Cloning and expression analysis of RcUDPGTs genes in Tibetan Rhodiola crenulata |
Page:2015—2024 |
| 196. Different methods establish a rat model of morphine drug discrimination with a fixed ratio 10 |
Page:1921—1926 |
| 197. Qualitative and quantitative analysis of aristolochic acid components in nine Chinese medicinal materials containing toxic aristolochic substances |
Page:1980—1987 |
| 198. In vitro functional similarity assessment of a proposed biosimilar BAT1706 to bevacizumab |
Page:1927—1935 |
| 199. Establishment of enzymatic hydrolysis method of active Astragalus polysaccharides APS-Ⅱ and study on the immune activity of oligosaccharides after its degradation |
Page:1936—1944 |
| 200. The upregulation mechanism of OCT4 signaling by ID1 in colorectal cancer |
Page:1945—1952 |
| 201. Application progress of experimental animal model of humanized fecal microbiota transplantation in depression research |
Page:1865—1871 |
| 202. Research progress of natural drugs targeting mitochondrial autophagy against ischemic heart disease |
Page:1872—1879 |
| 203. Micro-particulate Ganoderma lucidum spore β-glucanin enhances the antitumor activity of gemcitabin via remodeling immunosuppressive microenvironment in Lewis lung cancer |
Page:1988—1998 |
| 204. Preparation and characterization of dissolving microneedles with nano-enhanced mechanical properties |
Page:1999—2004 |
| 205. Research advances on stimulator of interferon genes (STING) and its agonists |
Page:1880—1892 |
| 206. The role of licorice DXS knockout and overexpression in glycyrrhizic acid biosynthesis |
Page:2025—2032 |
| 207. Research progress on preparation technology of nanocrystal drugs |
Page:1902—1910 |
| 208. Paeoniae Rubra Radix decreases the hepatotoxicity of Psoraleae Fructus in an immunologically stressed rat model: a metabolic network analysis |
Page:1789—1796 |
| 209. Development of an overall evaluation system for traditional Chinese medicine |
Page:1749—1756 |
| 210. Synthesis and antibacterial activity of C-7 haloacyl cephalosporins |
Page:1965—1975 |
| 211. A new diarylheptane dimer from Zingiber officinale peel |
Page:1976—1979 |
| 212. Label-free quantitative proteomic study of RUNX3 regulating Herceptin resistance in gastric cancer cells |
Page:1953—1964 |
| 213. Development of a liquid-liquid microextraction GC-MS method for simultaneous determination and pharmacokinetic analysis of β- elemene in rat plasma after administration of citronella grass extract |
Page:1820—1825 |
| 214. Identification of Gastrodiae Rhizoma chromatographic peaks identification by liner calibration with two reference substances assisted |
Page:1797—1803 |
| 215. Effect of Chuanxiong Rhizoma on the absorption and clearance of four coumarins in Angelicae Dahuricae Radix |
Page:1804—1810 |
| 216. Therapeutic prospect of tetrandrine against SARS-CoV-2 based on its pulmonary pharmacology and exposure character |
Page:1769—1777 |
| 217. Research progress on the traditional Chinese medicine-pharmaceutical drug interaction mediated by the ABC transporter family |
Page:1778—1788 |
| 218. Metabolism characteristics and pharmacological insights of flavonoids based on the intestinal bacteria |
Page:1757—1768 |
| 219. Paeoniflorin regulates gut microbiota and bile acids metabolism in colitis mice |
Page:1811—1819 |
| 220. Direct acting substances discovery of estrogen effect of Cuscuta chinensis in vivo |
Page:1826—1831 |
| 221. Research progress of plant-derived vesicles and their biomedical applications |
Page:2039—2047 |
| 222. Research advances on the chemical components and pharmacological activities of Zanthoxyli Radix |
Page:2169—2181 |
| 223. Progress on the application of artificial intelligence technology in ligand-based and receptor structure-based drug screening |
Page:2136—2145 |
| 224. Research advances on the effect of ginsenoside Rg1 on angiogenesis and vascular protection |
Page:2146—2153 |
| 225. Molecular authentication of the medicinal species of Rhizoma et Radix Heraclei, Radix Angelicae Sinensis, Radix Angelicae Pubescentis and Rhizoma et Radix Notopterygii by integrating ITS2 and its secondary structure |
Page:2289—2294 |
| 226. Analysis of fungal diversity on the surface of Armeniacae Semen Amarum using a DNA metabarcoding technique |
Page:2295—2301 |
| 227. Interlaboratory method validation of HPLC-FMA for determination of polysorbate 80 in monoclonal antibodies |
Page:2276—2281 |
| 228. Application of bioisostere difluoromethyl in medicinal chemistry and the research progress in its synthetic methods |
Page:2182—2196 |
| 229. Anwulignan alleviates liver damages in exhausted mice by activating NRF2 |
Page:2230—2240 |
| 230. Phospholipid peroxidation: a key factor in "susceptibility" to neurodegenerative diseases |
Page:2154—2163 |
| 231. Guidelines investigation and technical considerations of virus safety during investigational new drug application of innovative monoclonal antibody products |
Page:2308—2314 |
| 232. The effect of acute hypobaric hypoxia on bile acid composition in the small intestine of rats |
Page:2260—2265 |
| 233. Desorption electrospray ionization-mass spectrometry in the analysis of natural medicines |
Page:2204—2216 |
| 234. Based on weak bond chemistry, the interaction mechanism between glycyrrhiza protein and berberine in water decocting process of Rhizoma Coptidis and Liquorice was investigated |
Page:2119—2126 |
| 235. The protective role of IMM-H004 on hepatic ischemia-reperfusion injury in mice |
Page:2217—2222 |
| 236. Physiologically-based pharmacokinetic modeling for predicting drug-drug interactions induced by acid-reducing agents |
Page:2197—2203 |
| 237. Protopine inhibits the growth of hepatocellular carcinoma through a mitochondrially mediated apoptosis pathway |
Page:2223—2229 |
| 238. Preparation, characterization and in vitro release of berberine hydrochloride resin complex |
Page:2282—2288 |
| 239. Methyl jasmonate stimulates the synthesis and accumulation of asperosaponin VI in the roots of Dipsacus asper |
Page:2302—2307 |
| 240. Ophiopogonin D interferes with ferroptosis to reduce the damage of cardiomyocytes induced by ophiopogonin D' |
Page:2241—2247 |
| 241. Secondary metabolites of endophyte Alternaria sp. W-1 from Laminaria japonica |
Page:2248—2251 |
| 242. Improving compactibility properties of Lonicera Japonica Flos by Plasdone S-630 |
Page:2127—2135 |
| 243. Design, synthesis, and activity study of α-conotoxin A10LPnIA fluorescent probe |
Page:2252—2259 |
| 244. Structure and identification of immune fragments of acid-degraded oligosaccharides from active Astragalus polysaccharides APS-Ⅱ |
Page:2266—2275 |
| 245. Preparation and properties of extracellular vesicle-like nanoparticles from medicinal and edible plants |
Page:2086—2092 |
| 246. Self-assembly performance of triterpene natural small molecules and their application in synergistic antitumor chemotherapy |
Page:2102—2111 |
| 247. Mechanism of pulmonary artery remodeling induced by calcium overload induced by hypoxia |
Page:2164—2168 |
| 248. The effect of Moutan cortex carbonisata nano-components on the blood-cooling and hemostatic |
Page:2093—2101 |
| 249. The overview of the property system and characterization techniques of Chinese medicine materials before the pharmaceutical |
Page:2048—2058 |
| 250. Research progress and thinking on improving physicochemical properties and efficacy of the active ingredients in traditional Chinese medicine based on crystal structure |
Page:2059—2069 |
| 251. Spatial heterogeneity and physical structure basis of antibacterial activity of Ma-Xing-Shi-Gan Decoction |
Page:2112—2118 |
| 252. The research progress on the structure pharmaceutics and dosage form structures of traditional Chinese medicines |
Page:2070—2085 |
| 253. Research progress of cyclic peptides derived from phage display technology |
Page:1253—1264 |
| 254. Effect of molecular weight of polyethylene glycol on pharmacokinetics of baicalin |
Page:1416—1423 |
| 255. Advances in research on inhibitors based on targets: IDO1 and TDO |
Page:1265—1278 |
| 256. Influencing factors and evaluation methods of skin microchannels formation and closure after microneedles application |
Page:1293—1300 |
| 257. Research progress in the application of glass transition phenomenon in pharmaceutics |
Page:1301—1313 |
| 258. Nucleocytoplasmic transport and neurodegenerative diseases |
Page:1217—1228 |
| 259. Zebularine induces apoptosis of esophageal cancer cells via demethylation SFRP2/Dkk3 to regulate Wnt/β-catenin signaling pathway |
Page:1384—1390 |
| 260. EGFR exon 20 insertion mutation in non-small cell lung cancer: classification and clinical treatment research |
Page:1201—1210 |
| 261. Application of environmentally sensitive hydrogels in drug delivery |
Page:1314—1331 |
| 262. Inhibitory effect of Qing-Fei-Pai-Du decoction on coronavirus in vitro |
Page:1400—1408 |
| 263. Cloning and expression analysis of delta-12 fatty acid desaturase gene in Coix lacryma-jobi L. |
Page:1478—1485 |
| 264. Effect of compound houttuynia mixture on influenza virus in vitro |
Page:1409—1415 |
| 265. Glycyrrhizic acid: a potential drug against COVID-19 |
Page:1211—1216 |
| 266. Drugs and drug delivery strategies for treatment of pulmonary arterial hypertension |
Page:1332—1342 |
| 267. Identification and expression analysis of the C2H2 gene family in Cannabis sativa L. |
Page:1486—1496 |
| 268. Full-factor design of experiment application in the development of printing ink for binder jetting 3D printed preparation |
Page:1460—1469 |
| 269. A novel dimeric diterpenoid alkaloid from the Tibetan medicinal plant Aconitum tanguticum (Maxim.) Stapf |
Page:1429—1433 |
| 270. Degrading enzyme modified molecularly imprinted xerogel for selective adsorption and degradation of dopamine |
Page:1470—1477 |
| 271. Determination of bis(2-chloroethyl)amine hydrochloride and 1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine hydrochloride in trazodone hydrochloride by UPLC-MS/MS |
Page:1439—1443 |
| 272. Recent studies on the natural products with xanthine oxidase inhibitory effect |
Page:1229—1237 |
| 273. Chemical composition and hypoglycemic activity of Edgeworthia gardneri |
Page:1434—1438 |
| 274. Puerarin ameliorates depressive symptoms in diabetic mice induced by high-fat diet |
Page:1391—1399 |
| 275. Recent advances in novel anticancer agents targeting β-catenin/TCF4 interaction for molecular cancer therapeutics |
Page:1238—1245 |
| 276. Development of a novel and practical bioassay for the quality evaluation and control of Galli Gigerii Endothelium Corneum based on the detection of digestive enzyme activity |
Page:1453—1459 |
| 277. Application of DNA barcoding technology to national drug sampling inspection |
Page:1497—1508 |
| 278. Assessment strategies for drug permeability during drug discovery and development |
Page:1279—1285 |
| 279. Puerarin protects against myocardial ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via TLR4/Myd88/NF-κB pathway in rats |
Page:1343—1351 |
| 280. TRIB3 promotes lung cancer cell survival and inhibits apoptosis through NRF2 activation |
Page:1352—1359 |
| 281. Structure modification and antimicrobial activity of novel cationic melittin analogues |
Page:1424—1428 |
| 282. Metabolomic investigation of secondary metabolites of prepared slices of Glycyrrhiza uralensis with different degrees of honey processing |
Page:1444—1452 |
| 283. Application of stable isotope-resolved metabolomics in glucose catabolism |
Page:1286—1292 |
| 284. The role of HIF-VEGF-Ang-2 signal transduction-mediated synovial angiogenesis in rheumatoid arthritis |
Page:1246—1252 |
| 285. Discovery of a small-molecule activator of beclin-1 that induces autophagy-associated cell death and apoptosis in triple negative breast cancer |
Page:1369—1383 |
| 286. Dynamic change of hepatocyte during PXR-induced liver enlargement |
Page:1360—1368 |
| 287. Network pharmacology integrates the differential genes of macrophages to explain the mechanism of patchouli oil treating IBD |
Page:3473—3483 |
| 288. Anti-tumor nanoscale drug delivery systems based on photodynamic therapy |
Page:3421—3430 |
| 289. Research progress of natural polysaccharides and their nano-sized drug delivery systems in regulating tumor microenvironment |
Page:3212—3223 |
| 290. Advances in nanocrystal technology and its application to improve the pharmacological efficacy for poorly-water soluble drugs |
Page:3431—3440 |
| 291. Research progress on diarrhea induced by molecular-targeted agents |
Page:3377—3384 |
| 292. Progress in the pleiotropic activity of metformin |
Page:3385—3391 |
| 293. Current drug research on intestinal mucosal healing in inflammatory bowel disease based on macrophage regulation |
Page:3392—3400 |
| 294. Bacterial outer membrane vesicles: a new approach to diseases therapy |
Page:3441—3450 |
| 295. Research progress of poly (β-amino ester)s-based gene vector |
Page:3451—3459 |
| 296. Different development phase of transcriptome analysis from Crataegus pinnatifida Bge. and cloning, structure and function prediction of squalene epoxidase involved in triterpenic acid biosynthesis |
Page:3313—3324 |
| 297. Study on the determination method and antioxidant activity of the multi-component contents of the classical prescription Qingzao Jiufei Decoction |
Page:3511—3517 |
| 298. Carrier-free nanoparticles based on self-assembly of active ingredients from Chinese medicine |
Page:3203—3211 |
| 299. The influence of pressure range on the fitting results of tablet compression equation |
Page:3547—3554 |
| 300. Use of network pharmacology to analyze compound reserpine and triamterene tablets in the treatment of hypertension |
Page:3484—3492 |
| 301. Pharmacokinetics of the main components differing between Ligustri Lucidi Fructus and its wine-steamed product |
Page:3518—3525 |
| 302. Comparative analysis of chemical constituents in hawthorn leaves from different sources |
Page:3526—3539 |
| 303. Identification and expression analysis of the DaNAC transcription factor family in Dipsacus asper |
Page:3325—3330 |
| 304. Research methods of miRNA in plants and research progress of miRNA in medicinal plants |
Page:3460—3472 |
| 305. Differences in the chemical composition of Dendrobium officinale Kimura et Migo and Dendrobium crepidatum Lindl based on UPLC-Q-TOF-MS/MS and metabolomics |
Page:3331—3344 |
| 306. Discovery and functional characterization of flavone O-glycosyltransferases in Scutellaria baicalensis |
Page:3345—3352 |
| 307. Transcriptome analysis to identify genes involved in the biosynthesis of aconitines in Aconitum pendulum |
Page:3353—3361 |
| 308. Cloning and functional characterization of isopentenyl diphosphate isomerase genes from Panax vietnamensis var. fuscidiscus |
Page:3362—3369 |
| 309. Quality evaluation of compound Chinese medicines as related to clinical efficacy |
Page:3414—3420 |
| 310. A new research paradigm in modernization of traditional Chinese medicine: single cell pharmacology |
Page:3300—3312 |
| 311. A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of ZSP1601, a novel pan-phosphodiesterase inhibitor |
Page:3540—3546 |
| 312. Research progress of febuxostat derivatives as xanthine oxidase inhibitors |
Page:3401—3413 |
| 313. Construction of targeted cryptotanshinone liposomes and research on its in vitro anti-glioma effect |
Page:3268—3276 |
| 314. Synthesis, bioactivity evaluation of dibenzoyl methane halophenols and their interactions with CAV-1 |
Page:3493—3502 |
| 315. Preparation and characterization of biomimetic liposomes coated with erythrocyte membrane co-loading triptolide and celastrol |
Page:3252—3260 |
| 316. The development of folate modified squalene-chidamide prodrug self-assembled nanoparticles to enhance the drug delivery in pancreatic cancer microenvironment |
Page:3261—3267 |
| 317. Preparation of mitochondrial targeted calcium arsenite/doxorubicin lipid nanoparticles and the in vitro study in reversing tumor drug resistance |
Page:3243—3251 |
| 318. Study on alkaloid constituents of Stephania tetrandra S. Moore |
Page:3503—3510 |
| 319. The anti-glioma effects of borneol and RGD co-modified docetaxel loaded nanoparticles after intranasal administration |
Page:3233—3242 |
| 320. Mechanism of tanshinone IIA to prevent spontaneous breast cancer in mice |
Page:3277—3284 |
| 321. In vitro and in vivo evaluation of folate-mediated triptolide exosome targeted delivery system against malignant melanoma |
Page:3224—3232 |
| 322. Identification and functional characterization of 2,3-oxidosqualene cyclase genes family in Tripterygium wilfordii |
Page:3370—3376 |
| 323. Biopathway construction of plant natural products |
Page:3285—3299 |
