WPRIM Management System> DCMS> Acta Pharmaceutica Sinica> 2021> 56> 2

Volume: 56 Issue: 2

1. Pharmacokinetic/pharmacodynamic modeling of the antitumor action of bispecific CD3/EpCAM antibody M701 in human colorectal cancer xenograft mice Page:538—544
2. Updated research progress of selective PPARγ modulators Page:352—359
3. Research progress on small molecule kinase inhibitors Page:414—431
4. Metabolic module identification and biological mechanism of Xiaoyaosan for treatment of depression Page:528—537
5. Current status and future of drugs targeting platelets-tumor cells interactions Page:360—367
6. Progress in tumor microenvironment responsive nano-platforms for cancer theranostics Page:465—475
7. Research progress in multi-targeted anti-tumor natural products Page:403—413
8. Preparation and anti-tumor activity of a novel antibody-drug conjugate 607-LDM Page:496—502
9. Research progress on metabolism and efficacy of small molecular prodrug nanosystems responsive to tumor redox microenvironment Page:476—486
10. Lead compound optimization strategy (8) - drug transporters and related drug design strategies Page:432—444
11. Mechanistic study on the solubility enhancement of puerarin by coamorphous technology Page:585—592
12. Advances in the optimization of the linker in proteolysis-targeting chimeras (PROTAC) Page:445—455
13. Research advances on the protective effects and mechanism of salvianolic acids against ischemic heart disease Page:368—373
14. Preparation and enhanced photodynamic therapy of supramolecular nanoparticles to overcome tumor hypoxia Page:593—603
15. Research advances in the effect and utilization of protein corona on the circulation of nanoparticles in vivo Page:487—495
16. Identification and application of biomarkers in life cycle of drugs Page:456—464
17. Cloning and bioinformatic analysis of the 3-ketoacyl-CoA synthase gene in Coix lacryma-jobi L. Page:610—617
18. Complete plastid genomes of Bupleurum chinense DC. and B. boissieuanum H. Wolff, with comparative and phylogenetic analyses of medicinal Bupleurum species Page:618—629
19. Simultaneous quantitative analyses of six components in Astragalus membranaceus based on HPLC-CAD and quantitative analysis of multi-components with a single-marker Page:557—564
20. Value assignment study on bioactivity of monoclonal antibody working reference standard Page:565—569
21. Identification of small molecule sirtuin-1 inhibitors for treating acute myeloid leukemia based on molecular docking, quantitative structure-activity relationships and molecular dynamics Page:545—552
22. Preparation, characterization and improved solubility of ticagrelor salts Page:570—576
23. Recent advancement in targeting the KRAS-G12C mutant for cancer therapy Page:374—382
24. Construction of a drug screening model for miscarriage from induced pluripotent stem cells in vitro Page:503—510
25. A new dimeric benzylisoquinoline alkaloid from Corydalis yanhusuo Page:553—556
26. Cloning and expression analysis of chalcone isomerase from Aquilaria sinensis Page:630—638
27. Rutaecarpine exerted anti-osteroporosis Page:511—519
28. Bruceantin inhibits proliferation, migration and invasion of non-small cell lung cancer H1299 cells by up-regulating miR-29a-3p Page:520—527
29. Synaptic pruning mediated by glia in Alzheimer's disease Page:383—390
30. Role of gut microbiota in the treatment of ulcerative colitis with traditional Chinese medicine Page:391—402
31. Establishment of a cocrystal characterization method for sacubitril valsartan sodium Page:577—584
32. Preparation and targeting capability of corona forming in human ovarian plasma Page:604—609
33. First-in-class small molecule drugs in 2020 Page:341—351